Biosynthesis of reduced graphene oxide and its in-vitro cytotoxicity against cervical cancer (HeLa) cell lines

2017 ◽  
Vol 78 ◽  
pp. 198-202 ◽  
Author(s):  
Lan Luo ◽  
Lina Xu ◽  
Haibo Zhao
Keyword(s):  
Cervical Cancer ◽  
Graphene Oxide ◽  
Hela Cell ◽  
Reduced Graphene Oxide ◽  
Cell Lines ◽  
In Vitro Cytotoxicity ◽  
Hela Cell Lines ◽  
Reduced Graphene

scholarly journals In vitro Cytotoxicity Studies of Zn (Zinc) Nanoparticles Synthesized from Abutilon indicum L. against Human Cervical Cancer (HeLa) Cell Lines.

2016 ◽  
Vol 8 (2) ◽  
pp. 127-131 ◽  
Author(s):  
Badarinath Druvarao Kulkarni ◽  
Samim Sultana ◽  
Mayuri Bora ◽  
Ishita Dutta ◽  
Padmaa Milaap Paarakh ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Hela Cell ◽  
Cell Lines ◽  
In Vitro Cytotoxicity ◽  
Zinc Nanoparticles ◽  
Cytotoxicity Studies ◽  
Hela Cell Lines ◽  
Human Cervical Cancer ◽  
Abutilon Indicum

Effect of black seeds (Nigella sativa) volatile oil on the cervical cancer: In vitro study, on Hela cell lines

2019 ◽  
Vol 7 (4) ◽  
pp. 91-96
Author(s):  
Isra'a Al-sobhi ◽  
◽  
Rawan Al-Ghabban ◽  
Soad Shaker Ali ◽  
Jehan Al-Amri ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Hela Cell ◽  
Cell Lines ◽  
Nigella Sativa ◽  
In Vitro Study ◽  
Volatile Oil ◽  
Vitro Study ◽  
Hela Cell Lines ◽  
Black Seeds

Synthesized β-cyclodextrin modified graphene oxide (β-CD-GO) composite for adsorption of cadmium and their toxicity profile in cervical cancer (HeLa) cell lines

2020 ◽  
Vol 93 ◽  
pp. 28-35 ◽  
Author(s):  
Melvin S. Samuel ◽  
E. Selvarajan ◽  
Kalidass Subramaniam ◽  
Thangavel Mathimani ◽  
Sangeetha Seethappan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Graphene Oxide ◽  
Hela Cell ◽  
Cell Lines ◽  
Toxicity Profile ◽  
Hela Cell Lines ◽  
Modified Graphene Oxide ◽  
Modified Graphene

scholarly journals In-vitro Cytotoxicity and In-silico Insights of the Multi-target Anticancer Candidates from Haplophyllum tuberculatum

2021 ◽  
Vol 4 (3) ◽  
pp. 192-201
Author(s):  
Mosab Yahya Al-Nour ◽  
Ahmed H Arbab ◽  
Mohammad Khalid Parvez ◽  
Arwa Y Mohamed ◽  
Mohammed S Al-Dosari
Keyword(s):  
Hela Cell ◽  
Anticancer Activity ◽  
Cell Lines ◽  
In Vitro Cytotoxicity ◽  
Binding Modes ◽  
Web Servers ◽  
Hela Cell Lines ◽  
Ic50 Values ◽  
Haplophyllum Tuberculatum

This study aimed to investigate the anticancer activity of Haplophyllum tuberculatum(Forsk.) aerial parts ethanol extract and fractions and reveal the potential anticancer targets, binding modes, pharmacokinetics, and toxicity properties of its phytoconstituents. MTT assay was used to investigate the anticancer activity. TargetNet, ChemProt version 2.0, and CLC-Pred web servers were used for virtual screening, and Cresset Flare software was used for molecular docking with the 26 predicted targets. Moreover, pkCSM, swiss ADME, and eMolTox web servers were used to predict pharmacokinetics and safety. Ethanolic extracts of H. tuberculatum on HepG2 and HeLa cell lines showed promising activities with IC50 values 54.12 and 48.1 µg/mL, respectively. Further, ethyl acetate fraction showed the highest cytotoxicity on HepG2 and HeLa cell lines with IC50 values 41.7 and 52.31 µg/mL. Of 70 compounds screened virtually, polygamain, justicidin A, justicidin B, haplotubine, kusunokinin, and flindersine were predicted as safe anticancer drugs candidates. They showed the highest binding scores with targets involved in cell growth, proliferation, survival, migration, tumor suppression, induction of apoptosis, metastasis, and drug resistance. Our findings revealed the potency of H. tuberculatum as a source of anticancer candidates that further studies should support.

Silk sericin induced fabrication of reduced graphene oxide and its in-vitro cytotoxicity, photothermal evaluation

2018 ◽  
Vol 186 ◽  
pp. 189-196 ◽  
Author(s):  
Sireesh Babu Maddinedi ◽  
Jegatheeswaran Sonamuthu ◽  
Serap SuzuK Yildiz ◽  
Guobin Han ◽  
Yurong Cai ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
In Vitro Cytotoxicity ◽  
Silk Sericin ◽  
Reduced Graphene

scholarly journals Green synthesis of graphene nanosheets and their in vitro cytotoxicity against human prostate cancer (DU 145) cell lines

2017 ◽  
Vol 7 ◽  
pp. 184798041770279 ◽  
Author(s):  
Xin Zhu ◽  
Xiaolin Xu ◽  
Feng Liu ◽  
Jizhong Jin ◽  
Lintao Liu ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Graphene Nanosheets ◽  
In Vitro Cytotoxicity ◽  
Biological Study ◽  
Citrullus Colocynthis ◽  
Graphene Oxide Nanosheets ◽  
Green Approach ◽  
Reduced Graphene

A simple and green approach for the synthesis of polyphenol-functionalized reduced graphene oxide nanosheets is demonstrated, using leaf extract of Citrullus colocynthis as a deoxygenating agent. The C. colocynthis polyphenols also play a significant role as a stabilizing agent, preventing agglomeration of reduced graphene oxide nanosheets. Cytotoxicity tests showed that the both graphene oxide and Citrullus colocynthis polyphenol-stabilized reduced graphene oxide were toxic to DU145 cells; the cytotoxicity was dose dependent. Hence, C. colocynthis–mediated reduced graphene oxide may be an ideal anticancer material for biological study applications.

Unpredicted formation of copper(ii) complexes containing 2-thiophen-2-yl-1-thiophen-2-ylmethyl-1H-benzoimidazole and their most promising in vitro cytotoxicity in MCF-7 and HeLa cell lines over cisplatin

2017 ◽  
Vol 41 (17) ◽  
pp. 8885-8898 ◽  
Author(s):  
P. Naveen ◽  
Ruchi Jain ◽  
P. Kalaivani ◽  
R. Shankar ◽  
F. Dallemer ◽  
...  
Keyword(s):  
Hela Cell ◽  
Cell Lines ◽  
Sodium Azide ◽  
In Vitro Cytotoxicity ◽  
Hela Cell Lines ◽  
Mcf 7

An in situ reaction of CuCl2·2H2O, o-phenylenediamine, thiophene-2-carbaldehyde and sodium azide in methanol afforded complex 1a.

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