Nano‑calcium phosphate bone cement based on Si-stabilized α-tricalcium phosphate with improved mechanical properties

2017 ◽  
Vol 81 ◽  
pp. 532-541 ◽  
Author(s):  
M. Roozbahani ◽  
M. Alehosseini ◽  
M. Kharaziha ◽  
R. Emadi
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Calcium Phosphate Bone Cement

Improving osteogenesis of calcium phosphate bone cement by incorporating with manganese doped β-tricalcium phosphate

2020 ◽  
Vol 109 ◽  
pp. 110481 ◽  
Author(s):  
Tingting Wu ◽  
Haishan Shi ◽  
Yongyi Liang ◽  
Teliang Lu ◽  
Zefeng Lin ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Calcium Phosphate Bone Cement

Physicochemical and Mechanical Properties of Composite of Chitosan Microspheres/Calcium Phosphate Cement

2007 ◽  
Vol 336-338 ◽  
pp. 1654-1657
Author(s):  
Rui Liu ◽  
Li Min Dong ◽  
Qing Feng Zan ◽  
Chen Wang ◽  
Jie Mo Tian
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Chemical Properties ◽  
Phase Evolution ◽  
Chitosan Microspheres ◽  
Setting Times ◽  
Calcium Phosphate Bone Cement

The aim of this work is to improve the mechanical properties of calcium phosphate bone cement (CPC) by appending chitosan microspheres to CPC base. That chitosan degrades rapidly than bone cement has been proved by previous investigations. Porous CPC has low compressive strength because of the pores in it weakening the structure. Additive chitosan microspheres can improve the mechanical properties by bearing the compress with the CPC base and produce pores after degradation. This study investigates the effect of chitosan microspheres on the setting time, mechanical properties, phase evolution and morphology of CPC. The additive proportion of chitosan microspheres ranges from 0 wt% to 30 wt%. Compared with original CPC, the modified CPC has higher compressive strength, without significantly affecting the chemical properties. The phase composition of the CPC is tested by XRD. The microstructures of CPC are observed using SEM. The final setting times range from 5~15 minutes and can be modulated by using different liquid and powder (L/P) ratio.

scholarly journals In Vivo Study of Tricomponent Resorbable Calcium Phosphate Bone Cement Based on Tricalcium Phosphate

2014 ◽  
pp. 72-77
Author(s):  
National Research Mamonov ◽  
National Research Chemis ◽  
National Research Drize ◽  
National Research Proskurina ◽  
I. I. Kryazhkov ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Bone Defects ◽  
Morphologic Study ◽  
Hemostatic Effect ◽  
Calcium Phosphate Bone Cement ◽  
Intertrabecular Space ◽  
Peripheral Bone

Results of experimental morphologic study of tricomponent resorbable calcium phosphate bone cement (CPhC), based on tricalcium phosphate for the filling of defect as a temporary bearing resorbable matrix are presented. Study was performed on soviet chinchilla rabbits weighting 3200-3500 g. The model of critical spongy bone defect was used. At different observation terms (6, 9 and 12 months) gradual substitution of biomaterial with newly formed bone tissue from periphery to the center was observed with complete cement resorption 12 months after surgery. By mechanic characteristics newly formed bone in the defect was stronger than the surrounding trabecular one. It was stated that material possessed hemostatic effect and moderate toxicity. Peripheral bone marrow maintained its cellularity at all terms, gradually filling intertrabecular space of newly formed bone. Achieved data enable to recommend wide used of CPhC for bone defects substitution.

scholarly journals In Vivo Study of Tricomponent Resorbable Calcium Phosphate Bone Cement Based on Tricalcium Phosphate

2014 ◽  
Vol 21 (1) ◽  
pp. 72-77
Author(s):  
National Research Center for Hematology, Moscow, RF Mamonov ◽  
National Research Center for Hematology, Moscow, RF Chemis ◽  
National Research Center for Hematology, Moscow, RF Drize ◽  
National Research Center for Hematology, Moscow, RF Proskurina ◽  
I. I Kryazhkov ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Bone Defects ◽  
Morphologic Study ◽  
Hemostatic Effect ◽  
Calcium Phosphate Bone Cement ◽  
Intertrabecular Space ◽  
Peripheral Bone

Results of experimental morphologic study of tricomponent resorbable calcium phosphate bone cement (CPhC), based on tricalcium phosphate for the filling of defect as a temporary bearing resorbable matrix are presented. Study was performed on soviet chinchilla rabbits weighting 3200-3500 g. The model of critical spongy bone defect was used. At different observation terms (6, 9 and 12 months) gradual substitution of biomaterial with newly formed bone tissue from periphery to the center was observed with complete cement resorption 12 months after surgery. By mechanic characteristics newly formed bone in the defect was stronger than the surrounding trabecular one. It was stated that material possessed hemostatic effect and moderate toxicity. Peripheral bone marrow maintained its cellularity at all terms, gradually filling intertrabecular space of newly formed bone. Achieved data enable to recommend wide used of CPhC for bone defects substitution.

scholarly journals Biocompatibility of calcium phosphate bone cement with optimized mechanical properties

2015 ◽  
Vol 104 (2) ◽  
pp. 308-315 ◽  
Author(s):  
Iwan Palmer ◽  
John Nelson ◽  
Wolfgang Schatton ◽  
Nicholas J. Dunne ◽  
Fraser J. Buchanan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Calcium Phosphate Bone Cement

scholarly journals Photoluminescent Eu3+-Doped Calcium Phosphate Bone Cement and Its Mechanical Properties

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1610 ◽  
Author(s):  
Annemarie Oesterle ◽  
Anne Boehm ◽  
Frank Müller
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Bone Cements ◽  
X Ray ◽  
Novel Approach ◽  
Calcium Phosphate Bone Cement ◽  
Negative Effect ◽  
Healing Processes

Calcium phosphate cements (CPC) are well-established bone replacement materials that have been used in dentistry and orthopedics for more than 25 years. The monitoring of bone cements and the associated healing processes in the human body is difficult and so far has often been achieved using cytotoxic X-ray contrast agent additives. These additives have a negative effect on the mechanical properties and setting time of the bone cement. In this paper, we present a novel approach to prepare contrastive CPC by the incorporation of luminescent Eu3+-doped hydroxyapatite (Eu:HAp) nanoparticles. Eu-doped CPC (Eu:CPC) exhibited enhanced mechanical properties compared to pure CPC. Furthermore, the red photoluminescence of Eu:CPC may allow the observation of CPC-related healing processes without the use of harmful ionizing radiation.

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