scholarly journals Biocompatibility of calcium phosphate bone cement with optimized mechanical properties

2015 ◽  
Vol 104 (2) ◽  
pp. 308-315 ◽  
Author(s):  
Iwan Palmer ◽  
John Nelson ◽  
Wolfgang Schatton ◽  
Nicholas J. Dunne ◽  
Fraser J. Buchanan ◽  
...  
2007 ◽  
Vol 336-338 ◽  
pp. 1654-1657
Author(s):  
Rui Liu ◽  
Li Min Dong ◽  
Qing Feng Zan ◽  
Chen Wang ◽  
Jie Mo Tian

The aim of this work is to improve the mechanical properties of calcium phosphate bone cement (CPC) by appending chitosan microspheres to CPC base. That chitosan degrades rapidly than bone cement has been proved by previous investigations. Porous CPC has low compressive strength because of the pores in it weakening the structure. Additive chitosan microspheres can improve the mechanical properties by bearing the compress with the CPC base and produce pores after degradation. This study investigates the effect of chitosan microspheres on the setting time, mechanical properties, phase evolution and morphology of CPC. The additive proportion of chitosan microspheres ranges from 0 wt% to 30 wt%. Compared with original CPC, the modified CPC has higher compressive strength, without significantly affecting the chemical properties. The phase composition of the CPC is tested by XRD. The microstructures of CPC are observed using SEM. The final setting times range from 5~15 minutes and can be modulated by using different liquid and powder (L/P) ratio.


Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1610 ◽  
Author(s):  
Annemarie Oesterle ◽  
Anne Boehm ◽  
Frank Müller

Calcium phosphate cements (CPC) are well-established bone replacement materials that have been used in dentistry and orthopedics for more than 25 years. The monitoring of bone cements and the associated healing processes in the human body is difficult and so far has often been achieved using cytotoxic X-ray contrast agent additives. These additives have a negative effect on the mechanical properties and setting time of the bone cement. In this paper, we present a novel approach to prepare contrastive CPC by the incorporation of luminescent Eu3+-doped hydroxyapatite (Eu:HAp) nanoparticles. Eu-doped CPC (Eu:CPC) exhibited enhanced mechanical properties compared to pure CPC. Furthermore, the red photoluminescence of Eu:CPC may allow the observation of CPC-related healing processes without the use of harmful ionizing radiation.


Author(s):  
Iwan Palmer ◽  
John Nelson ◽  
Wolfgang Schatton ◽  
Nicholas J. Dunne ◽  
Fraser Buchanan ◽  
...  

2004 ◽  
Vol 15 (4) ◽  
pp. 451-455 ◽  
Author(s):  
A. Reinstorf ◽  
M. Ruhnow ◽  
M. Gelinsky ◽  
W. Pompe ◽  
U. Hempel ◽  
...  

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