Visualization and monitoring of damaging-healing processes of polymers by AIEgen-loaded multifunctional microcapsules

Polymeric materials play an essential and ubiquitous role in modern societies, but they are inevitably damaged during service, which can lead to compromised performance or even direct failure. The sensitive detection and dynamic monitoring of the health states of polymers is thus crucial to increase their reliability, safety, and lifetime. Herein, a facile fluorescence-based approach that can achieve the nondestructive, on-site, real-time, full-field, and sensitive visualization and monitoring of damaging-healing processes of polymers is demonstrated. By embedding novel UV-blocking microcapsules containing a diisocyanate solution of aggregation-induced emission luminogens (AIEgens) into a polymer matrix, the damaged regions of the composite show turn-on fluorescence and dual signal changes in both fluorescence intensity and fluorescence color can be observed during the healing processes. The invisible information of the static health states and dynamic healing processes can be directly and semi-quantitatively visualized by naked eyes based on the collective effects of AIE and twisted intramolecular charge transfer. In addition to the autonomous damage-reporting, self-healing, and health indication functionalities, the microcapsule-embedded polymeric coatings possess excellent photo- and water-protection capabilities, which are appealing to various practical applications.

LEADERSHIP ANALYSIS OF ‘GURULATIH’ AS A PRACTITIONER OF TRADITIONAL HEALING IN THE SENI SILAT PUSAKA GAYONG MALAYSIA IN KELANTAN ACCORDING TO MAX WEBER'S THEORY

A trainer plays a very important role in imparting silat martial arts knowledge to ensure the validity of the knowledge learned. In addition, trainers are also considered as a symbol of perfection and are accountable in self-defense institutions. Through this study, the researcher has conducted a more in-depth analysis of the leadership of trainers according to Max Weber's theoretical views in operating a martial arts organization, the existence of traditional healing processes in martial arts, identify the type of disease experienced by trainees and to see the effectiveness of treatment towards the patient. In this this study, the researcher utilised the participant-observant method and interviewing respondents consisting of martial arts trainers in Kelantan. As a result, the researcher found that a trainer not only plays a role in teaching martial arts but is also responsible in learning and practicing traditional treatment. This is important in elevating the status of a silat trainer as a respectable and trusted leader.

Black Ghosts of the Diasporic Memory in Jesmyn Ward’s Sing, Unburied, Sing

This article reads Jesmyn Ward’s Sing, Unburied, Sing (2017) as a novel that follows an African American family facing the ghosts of their past and present to resurrect buried stories that are unrelentingly interlocked with the legacy of slavery and the draconian racist practices of Jim Crow. I posit that the novel participates in the re-examination of the trope of the ghost as a healing asset that needs to be accommodated within the retrieval of memory work. Thus, the enactment of this African diasporic memory facilitates the encounter with their ghosts so that the family can start their healing processes and be provided with the tools and examples of how to keep on coming to terms together with and against the legacy of slavery and the present racist practices.

Collective Healing to Address Legacies of Transatlantic Slavery: Opportunities and Challenges

In this article, we show how pathways to justice and reconciliation pertaining to the transatlantic slavery should begin with collective healing processes. To illustrate this conclusion, we first employ a four-fold conceptual framework for understanding collective healing that consists in: (1) acknowledging historical dehumanizing acts; (2) addressing the harmful effects of dehumanisation; (3) embracing relational rapprochement; and (4) co-imagining and co-creating conditions for systemic justice. Based on this framework, we then examine existing collective healing practices in different contexts that are aimed at addressing legacies of transatlantic slavery. In doing so, we further identify challenges and pose critical questions concerning such practices. While globally there are, and have been, many different kinds of racism and slavery, and even though transatlantic slavery has many features specific to it, nevertheless, we hope that this exploration of collective healing will be illuminating for other situations where acts of brutality have served to demean and dehumanize.

Collective Healing: Towards a Conceptual Framework

To understand what kind of collective healing practices might be most effective following mass atrocity, we need to comprehend better what counts as collective healing, and in what ways group healing processes differ from individual ones. We need clear and well-argued answers to these conceptual questions as a basis for deriving the criteria by which we might evaluate various practices in different contexts. Because means are valuable only in relation to ends, judging their effectiveness requires a definition of the ends in question and what is good about them. So, what counts as a good collective healing process? This conceptual paper proposes that the concept of healing requires that of being wounded, which in turn requires the idea that some agent performed dehumanizing actions. It identifies dehumanization as a serious form of harm, and characterizes the nature of healing processes based on this analysis. It then describes the group nature of mass atrocities. These four points enable us to separate different kinds of healing processes that are normally conflated and begin to provide a framework for evaluating diverse collective healing processes.

An Additively Manufactured Sample Holder to Measure the Controlled Release of Vancomycin from Collagen Laminates

The controlled release of antibiotics prevents the spread of pathogens and thereby improves healing processes in regenerative medicine. However, high concentrations may interfere with healing processes. It is therefore advantageous to use biodegradable materials for a controlled release. In particular, multilayer materials enable differential release at different surfaces. For this purpose, collagen sheets of different properties can be bonded by photochemical crosslinking. Here, we present the development and application of an easily accessible, additively manufactured sample holder to study the controlled release of vancomycin from modularly assembled collagen laminates in two directions. As proof-of-concept, we show that laminates of collagen sheets covalently linked by rose bengal and green light crosslinking (RGX) can be tightly inserted into the device without leakage from the upper to lower cavity. We used this sample holder to detect the release of vancomycin from symmetrically and asymmetrically loaded two-layer and three-layer collagen laminates into the upper and lower cavity of the sample holder. We show that these collagen laminates are characterized by a collagen type-dependent vancomycin release, enabling the control of antibiotic release profiles as well as the direction of antibiotic release.

WARISAN PERUBATAN TRADISIONAL DALAM SENI SILAT DI KELANTAN, MALAYSIA

AbstrakSilat merupakan seni mempertahankan diri yang terkenal dalam kalangan masyarakat Melayu dan tersebar luas di Nusantara. Namun, tidak semua dalam kalangan masyarakat mengetahui tentang adanya proses perubatan secara tradisional di dalam persilatan dan kedua-duanya amat memerlukan antara satu sama lain. Dalam erti kata lain, perubatan tradisional dalam seni silat telah bergerak seiring dengan pembelajaran ilmu silat dan berfungsi sebagai ikhtiar untuk menyembuhkan pelbagai jenis penyakit. Aktiviti perubatan tradisional di dalam persilatan ini juga masih lagi diamalkan di Kelantan, yang juga terkenal dengan ritual perubatan melalui seni persembahan seperti Main Puteri dan Mak Yong. Walau bagaimanapun proses perubatan dalam seni silat yang dikaji berbeza dengan Main Puteri dan Mak Yong di mana ia tidak dipertontonkan di hadapan khalayak ramai. Mengungkap secara lebih mendalam mengenai perubatan dalam seni silat, pengkaji akan menerangkan objektif kajian ini iaitu apakah jenis penyakit yang dialami oleh pesakit dan bagaimana proses perubatan dilakukan oleh gurulatih. Di samping itu, pengkaji telah menjalankan kaedah pemerhatian serta pemerhatian secara ikut serta dan menemubual beberapa orang gurulatih seni silat itu sendiri. AbstractSilat is an art of self-defense that is well known among the Malay community and is widespread throughout the Malay Archipelago. However, the society might not be aware that in silat there is a practice of traditional healing and both need one another. In other words, traditional healing in silat have been moving along with the learning aspect of the martial art and serves as an effort to cure several illnesses suffered by a patient. Silat healing activities are still being practiced in Kelantan, which is known for its traditional healing rituals through the performance of Main Teri and Mak Yong. The healing process in the Seni Silat Pusaka Gayong Malaysia, Kelantan branch is different from Main Teri and Mak Yong and can’t be shown to the public. In looking deeper into the healing process in silat, the researcher analyses the objectives of this study which covered the types of illnesses experienced by patients and how healing processes were done by the ‘gurulatih’. The research was conducted using the participant-observation method and interviews with a few silat ‘gurulatih’

High Numbers of CD163-Positive Macrophages in the Fibrotic Region of Exuberant Granulation Tissue in Horses

Exuberant granulation tissue (EGT) is a frequently encountered complication during second intention healing in equine distal limb wounds. Although it is still unknown what exactly triggers the formation of this tissue, previous research has revealed a persistent inflammatory response in these wounds. In this preliminary study we examined this inflammatory response in EGT-developing wounds as well as in experimental induced wounds. Immunohistological stainings were performed to detect primary inflammatory immune cells (MAC387 staining) as well as pro-resolution immune cells (CD163 staining). Our results show a significantly higher amount of MAC387+ and CD163+ cells in the fibrotic regions of EGT compared with the 19-day-old experimental wounds. This persistent high amount of fibrosis-promoting CD163+ cells in EGT suggests that the wound healing processes in EGT-developing wounds are arrested at the level of the proliferation phase.

Reparo de feridas na língua de camundongos jovens e velhos

Ageing affects several biological structures and mechanisms. The present work studied wound healing in 2 months old and 17 months old mice. Experimental wound in the tongue of 70 mice were performed. Histological diferences or similarities in healing ofyoung and aged mice were search. The results have shown that there were no ignificative differences on wound healing between young and aged groups. It was concluded that wound healing processes at the same rate independently of group age.