scholarly journals Photoluminescent Eu3+-Doped Calcium Phosphate Bone Cement and Its Mechanical Properties

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1610 ◽  
Author(s):  
Annemarie Oesterle ◽  
Anne Boehm ◽  
Frank Müller
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Bone Cements ◽  
X Ray ◽  
Novel Approach ◽  
Calcium Phosphate Bone Cement ◽  
Negative Effect ◽  
Healing Processes

Calcium phosphate cements (CPC) are well-established bone replacement materials that have been used in dentistry and orthopedics for more than 25 years. The monitoring of bone cements and the associated healing processes in the human body is difficult and so far has often been achieved using cytotoxic X-ray contrast agent additives. These additives have a negative effect on the mechanical properties and setting time of the bone cement. In this paper, we present a novel approach to prepare contrastive CPC by the incorporation of luminescent Eu3+-doped hydroxyapatite (Eu:HAp) nanoparticles. Eu-doped CPC (Eu:CPC) exhibited enhanced mechanical properties compared to pure CPC. Furthermore, the red photoluminescence of Eu:CPC may allow the observation of CPC-related healing processes without the use of harmful ionizing radiation.

Physicochemical and Mechanical Properties of Composite of Chitosan Microspheres/Calcium Phosphate Cement

2007 ◽  
Vol 336-338 ◽  
pp. 1654-1657
Author(s):  
Rui Liu ◽  
Li Min Dong ◽  
Qing Feng Zan ◽  
Chen Wang ◽  
Jie Mo Tian
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Chemical Properties ◽  
Phase Evolution ◽  
Chitosan Microspheres ◽  
Setting Times ◽  
Calcium Phosphate Bone Cement

The aim of this work is to improve the mechanical properties of calcium phosphate bone cement (CPC) by appending chitosan microspheres to CPC base. That chitosan degrades rapidly than bone cement has been proved by previous investigations. Porous CPC has low compressive strength because of the pores in it weakening the structure. Additive chitosan microspheres can improve the mechanical properties by bearing the compress with the CPC base and produce pores after degradation. This study investigates the effect of chitosan microspheres on the setting time, mechanical properties, phase evolution and morphology of CPC. The additive proportion of chitosan microspheres ranges from 0 wt% to 30 wt%. Compared with original CPC, the modified CPC has higher compressive strength, without significantly affecting the chemical properties. The phase composition of the CPC is tested by XRD. The microstructures of CPC are observed using SEM. The final setting times range from 5~15 minutes and can be modulated by using different liquid and powder (L/P) ratio.

Acrylic Bone Cements: New Insight and Future Perspective

2017 ◽  
Vol 745 ◽  
pp. 39-49 ◽  
Author(s):  
Simona Cavalu
Keyword(s):  
Mechanical Properties ◽  
Bone Cement ◽  
Bone Growth ◽  
Setting Time ◽  
Ceramic Composites ◽  
Future Perspective ◽  
Bone Cements ◽  
Main Function ◽  
Suture Materials ◽  
Artificial Joint Replacement

The history of acrylic bone cement comprise a long period of time, Sir John Charnley being considered the founder of modern artificial joint replacement, as he started to develop the cementing in the late 1950s. Acrylic bone cements (ACB) are polymer-ceramic composites based on polymethyl metacrylate (PMMA), widely used in orthopaedics as suture materials and fixation devices. The main features of these materials are: 1) biocompatibility and ability to support new bone growth (osteoconductive) and 2) bioactivity (ability to form a calcium phosphate layer on its surface). The main function of the cement is to serve as interfacial phase between the high modulus metallic implant and the bone, thereby assisting to transfer and distribute loads. During years of follow up, cemented prosthesis with acrylic bone cements (ABC) demonstrated a good primary fixation and load distribution between implant and bone, along with the advantage of fast recovery of the patient. However, several problems are still persisting, as the orthopedic acrylic bone cements have to meet several medical requirements, such as low values of maximum cure temperature in order to avoid thermal necrosis of the bone tissue during the setting time, appropriate setting time (so that cement does not cure too fast or too slowly) and high values of compressive strength in order to withstand the compressive loads involved by normal daily activities. Generally, the improvement mechanical properties can be realized in three directions: 1) by searching alternative material to PMMA acrylic bone cements; 2) chemical modification of PMMA; and 3) the reinforcement of PMMA by adding different bioactive particles, antimicrobials, vitamins. The aim of this rewiew is to explore the development of bone cements in the last decade, to highlight the role of bone cement additives with respect to mechanical properties and limitations of polymethylmethacrylate in orthopaedic surgery. The behavior of antibiotic-loaded bone cement is discussed, compared with other alternative additives including nanofillers, together with areas of research that are now open to explore new insights and applications of this well known biomaterial.

scholarly journals Костные цементы на основе системы фосфат кальция—фосфат магния с добавлением катионов серебра и цинка.

2020 ◽  
Vol 11 (3-2020) ◽  
pp. 103-107
Author(s):  
P. A. Krokhicheva ◽  
◽  
M. A. Goldberg ◽  
A. S. Baikin ◽  
D. R. Khayrutdinova ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Magnesium Oxide ◽  
Reconstructive Surgery ◽  
Salt Solution ◽  
Setting Time ◽  
Magnesium Phosphate ◽  
X Ray ◽  
Phosphate System ◽  
Phosphate Magnesium

The main highlights in this paper are about investigation of cation-dopped cements based on the calcium phosphate —magnesium phosphate system with a ratio of (Ca + Mg) / P = 2 containing 40 mol. % Mg for application in the reconstructive surgery. The powders were synthesized by the method of deposition from a salt solution, the powders were certified using the X-ray phaseanalysis (XRD), the main phases were the magnesium-substituted vitlokite phase (Ca2,589Mg0,411PO4), magnesium oxide MgO, and stanfeldite (Mg3Ca3(PO4)4. The setting time of cement samples with mixing phosphate fluid is 6–9 min; the high mechanical properties are exhibited by the samples with a content of 0,5 mass % Zn (26,5 ± 1,3 MPa).

scholarly journals Biocompatibility of calcium phosphate bone cement with optimized mechanical properties

2015 ◽  
Vol 104 (2) ◽  
pp. 308-315 ◽  
Author(s):  
Iwan Palmer ◽  
John Nelson ◽  
Wolfgang Schatton ◽  
Nicholas J. Dunne ◽  
Fraser J. Buchanan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Calcium Phosphate Bone Cement

scholarly journals Prediction of the Setting Properties of Calcium Phosphate Bone Cement

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Seyed Mahmud Rabiee ◽  
Hamid Baseri
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Bone Substitutes ◽  
Setting Times ◽  
Calcium Phosphate Bone Cement ◽  
Poly Ethylene ◽  
Predicted Values ◽  
Inference Systems ◽  
Glycol Solution

Setting properties of bone substitutes are improved using an injectable system. The injectable bone graft substitutes can be molded to the shape of the bone cavity and set in situ when injected. Such system is useful for surgical operation. The powder part of the injectable bone cement is included ofβ-tricalcium phosphate, calcium carbonate, and dicalcium phosphate and the liquid part contains poly ethylene glycol solution with different concentrations. In this way, prediction of the mechanical properties, setting times, and injectability helps to optimize the calcium phosphate bone cement properties. The objective of this study is development of three different adaptive neurofuzzy inference systems (ANFISs) for estimation of compression strength, setting time, and injectability using the data generated based on experimental observations. The input parameters of models are polyethylene glycol percent and liquid/powder ratio. Comparison of the predicted values and measured data indicates that the ANFIS model has an acceptable performance to the estimation of calcium phosphate bone cement properties.

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