Evaluation of the optimal dosage of BMP-9 through the comparison of bone regeneration induced by BMP-9 versus BMP-2 using an injectable microparticle embedded thermosensitive polymeric carrier in a rat cranial defect model

2021 ◽  
pp. 112252
Author(s):  
Bipin Gaihre ◽  
Angshuman Bharadwaz ◽  
Janitha M. Unagolla ◽  
Ambalangodage C. Jayasuriya
Keyword(s):  
Bone Regeneration ◽  
Optimal Dosage ◽  
Polymeric Carrier ◽  
Defect Model ◽  
Cranial Defect

A chemotactic functional scaffold with VEGF-releasing peptide amphiphiles facilitates bone regeneration by BMP-2 in large-scale rodent cranial defect model

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Reena Bakshi ◽  
Akishige Hokugo ◽  
Daniel Khalil ◽  
Lixin Wang ◽  
Yoichiro Shibuya ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Large Scale ◽  
Peptide Amphiphiles ◽  
Defect Model ◽  
Cranial Defect

Bone regeneration with glass ceramic implants and calcium phosphate cements in a rabbit cranial defect model

2010 ◽  
Vol 21 (10) ◽  
pp. 2853-2859 ◽  
Author(s):  
Gerlind Schneider ◽  
Karin Blechschmidt ◽  
Dirk Linde ◽  
Peter Litschko ◽  
Thomas Körbs ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Regeneration ◽  
Glass Ceramic ◽  
Defect Model ◽  
Calcium Phosphate Cements ◽  
Cranial Defect ◽  
Ceramic Implants

Molecular Mass‐Dependent Resorption and Bone Regeneration of 3D Printed PPF Scaffolds in a Critical‐Sized Rat Cranial Defect Model

2019 ◽  
Vol 8 (17) ◽  
pp. 1900646 ◽  
Author(s):  
Karissa Nettleton ◽  
Derek Luong ◽  
Alex P. Kleinfehn ◽  
Laura Savariau ◽  
Christopher Premanandan ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Molecular Mass ◽  
Defect Model ◽  
Cranial Defect ◽  
3D Printed ◽  
Mass Dependent

scholarly journals Bioglass-Incorporated Methacrylated Gelatin Cryogel for Regeneration of Bone Defects

Polymers ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 914 ◽  
Author(s):  
Song Kwon ◽  
Seunghun Lee ◽  
A. Sivashanmugam ◽  
Janet Kwon ◽  
Seung Kim ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Defects ◽  
Micro Ct ◽  
Defect Model ◽  
Cranial Defect ◽  
In Vivo Testing ◽  
Regeneration Of Bone ◽  
Adhesion Site

Cryogels have recently gained interest in the field of tissue engineering as they inherently possess an interconnected macroporous structure. Considered to be suitable for scaffold cryogel fabrication, methacrylated gelatin (GelMA) is a modified form of gelatin valued for its ability to retain cell adhesion site. Bioglass nanoparticles have also attracted attention in the field due to their osteoinductive and osteoconductive behavior. Here, we prepare methacrylated gelatin cryogel with varying concentration of bioglass nanoparticles to study its potential for bone regeneration. We demonstrate that an increase in bioglass concentration in cryogel leads to improved mechanical property and augmented osteogenic differentiation of mesenchymal cells during in vitro testing. Furthermore, in vivo testing in mice cranial defect model shows that highest concentration of bioglass nanoparticles (2.5 w/w %) incorporated in GelMA cryogel induces the most bone formation compared to the other tested groups, as studied by micro-CT and histology. The in vitro and in vivo results highlight the potential of bioglass nanoparticles incorporated in GelMA cryogel for bone regeneration.

scholarly journals Bacterial cellulose-hydroxyapatite composites with osteogenic growth peptide (OGP) or pentapeptide OGP on bone regeneration in critical-size calvarial defect model

2015 ◽  
Vol 103 (10) ◽  
pp. 3397-3406 ◽  
Author(s):  
Suzane C. Pigossi ◽  
Guilherme J. P. L. de Oliveira ◽  
Livia S. Finoti ◽  
Rafael Nepomuceno ◽  
Luis Carlos Spolidorio ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bacterial Cellulose ◽  
Critical Size ◽  
Calvarial Defect ◽  
Defect Model

scholarly journals Retraction note: Histopathological features of bone regeneration in a canine segmental ulnar defect model

2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Rahim Hobbenaghi ◽  
Pariya Mahboob ◽  
Siamak Saifzadeh ◽  
Javad Javanbakht ◽  
Javad Yaghoobi Yeganeh Manesh ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Defect Model ◽  
Histopathological Features
Sign in / Sign up

Export Citation Format

Share Document