scholarly journals Autologous stromal vascular fraction-loaded hyaluronic acid/gelatin-biphasic calcium phosphate scaffold for bone tissue regeneration

2021 ◽  
pp. 112533
Author(s):  
Seong-su Park ◽  
Myeong-ki Park ◽  
Tarek Saleh ◽  
Byong-Taek Lee
Keyword(s):  
Hyaluronic Acid ◽  
Calcium Phosphate ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Biphasic Calcium Phosphate ◽  
Stromal Vascular Fraction ◽  
Bone Tissue Regeneration

BMP-2 encapsulated polysaccharide nanoparticle modified biphasic calcium phosphate scaffolds for bone tissue regeneration

2014 ◽  
Vol 103 (4) ◽  
pp. 1520-1532 ◽  
Author(s):  
Zhenming Wang ◽  
Kefeng Wang ◽  
Xiong Lu ◽  
Minqi Li ◽  
Hongrui Liu ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Biphasic Calcium Phosphate ◽  
Bone Tissue Regeneration

scholarly journals Effect of Morphological Characteristics and Biomineralization of 3D-Printed Gelatin/Hyaluronic Acid/Hydroxyapatite Composite Scaffolds on Bone Tissue Regeneration

2021 ◽  
Vol 22 (13) ◽  
pp. 6794
Author(s):  
Jae-Woo Kim ◽  
Yoon-Soo Han ◽  
Hyun-Mee Lee ◽  
Jin-Kyung Kim ◽  
Young-Jin Kim
Keyword(s):  
Hyaluronic Acid ◽  
Bone Tissue ◽  
Double Layer ◽  
Tissue Regeneration ◽  
Great Influence ◽  
Morphological Characteristics ◽  
Bone Tissue Regeneration ◽  
Hierarchical Architecture ◽  
Uniform Structure ◽  
Composite Scaffolds

The use of porous three-dimensional (3D) composite scaffolds has attracted great attention in bone tissue engineering applications because they closely simulate the major features of the natural extracellular matrix (ECM) of bone. This study aimed to prepare biomimetic composite scaffolds via a simple 3D printing of gelatin/hyaluronic acid (HA)/hydroxyapatite (HAp) and subsequent biomineralization for improved bone tissue regeneration. The resulting scaffolds exhibited uniform structure and homogeneous pore distribution. In addition, the microstructures of the composite scaffolds showed an ECM-mimetic structure with a wrinkled internal surface and a porous hierarchical architecture. The results of bioactivity assays proved that the morphological characteristics and biomineralization of the composite scaffolds influenced cell proliferation and osteogenic differentiation. In particular, the biomineralized gelatin/HA/HAp composite scaffolds with double-layer staggered orthogonal (GEHA20-ZZS) and double-layer alternative structure (GEHA20-45S) showed higher bioactivity than other scaffolds. According to these results, biomineralization has a great influence on the biological activity of cells. Hence, the biomineralized composite scaffolds can be used as new bone scaffolds in bone regeneration.

Hierarchically microporous/macroporous scaffold of magnesium–calcium phosphate for bone tissue regeneration

Biomaterials ◽  
2010 ◽  
Vol 31 (6) ◽  
pp. 1260-1269 ◽  
Author(s):  
Jie Wei ◽  
Junfeng Jia ◽  
Fan Wu ◽  
Shicheng Wei ◽  
Huanjun Zhou ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration

Preparation of an rhBMP-2 loaded mesoporous bioactive glass/calcium phosphate cement porous composite scaffold for rapid bone tissue regeneration

2015 ◽  
Vol 3 (43) ◽  
pp. 8558-8566 ◽  
Author(s):  
Nan Li ◽  
Chuan Jiang ◽  
Xingdi Zhang ◽  
Xinfeng Gu ◽  
Jingwei Zhang ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bioactive Glass ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Calcium Phosphate Cement ◽  
Composite Scaffold ◽  
Early Stage ◽  
Bone Tissue Regeneration ◽  
Porous Composite ◽  
Mesoporous Bioactive Glass

An rhBMP-2/MBG/CPC scaffold is beneficial for rapid bone tissue regeneration in the early stage.

Photo-cured hyaluronic acid-based hydrogels containing growth and differentiation factor 5 (GDF-5) for bone tissue regeneration

Bone ◽  
2014 ◽  
Vol 59 ◽  
pp. 189-198 ◽  
Author(s):  
Min Soo Bae ◽  
Joo-Young Ohe ◽  
Jung Bok Lee ◽  
Dong Nyoung Heo ◽  
Wook Byun ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Differentiation Factor
Sign in / Sign up

Export Citation Format

Share Document