Distinction between auditory electrophysiological responses in type 1 and type 2 diabetic animal models

2014 ◽  
Vol 566 ◽  
pp. 309-314 ◽  
Author(s):  
Bin Na Hong ◽  
Tong Ho Kang
Keyword(s):  
Animal Models ◽  
Diabetic Animal ◽  
Electrophysiological Responses ◽  
Type 2 Diabetic

Beneficial effects of pyridoxamine in endothelial dysfunction of type 2 diabetic animal models

2021 ◽  
Vol 331 ◽  
pp. e100
Author(s):  
C. Sena ◽  
D. Carvalho ◽  
A. Pereira ◽  
M. Queiroz ◽  
R. Seiça
Keyword(s):  
Endothelial Dysfunction ◽  
Animal Models ◽  
Diabetic Animal ◽  
Beneficial Effects ◽  
Type 2 Diabetic

scholarly journals Spontaneous Type 2 Diabetic Rodent Models

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Yang-wei Wang ◽  
Guang-dong Sun ◽  
Jing Sun ◽  
Shu-jun Liu ◽  
Ji Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Health Care ◽  
Animal Models ◽  
Rodent Models ◽  
Advantages And Disadvantages ◽  
Characteristic Features ◽  
Type 2 Diabetic

Diabetes mellitus, especially type 2 diabetes (T2DM), is one of the most common chronic diseases and continues to increase in numbers with large proportion of health care budget being used. Many animal models have been established in order to investigate the mechanisms and pathophysiologic progress of T2DM and find effective treatments for its complications. On the basis of their strains, features, advantages, and disadvantages, various types of animal models of T2DM can be divided into spontaneously diabetic models, artificially induced diabetic models, and transgenic/knockout diabetic models. Among these models, the spontaneous rodent models are used more frequently because many of them can closely describe the characteristic features of T2DM, especially obesity and insulin resistance. In this paper, we aim to investigate the current available spontaneous rodent models for T2DM with regard to their characteristic features, advantages, and disadvantages, and especially to describe appropriate selection and usefulness of different spontaneous rodent models in testing of various new antidiabetic drugs for the treatment of type 2 diabetes.

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