scholarly journals Lifestyle activities in mid-life contribute to cognitive reserve in late-life, independent of education, occupation, and late-life activities

2018 ◽  
Vol 70 ◽  
pp. 180-183 ◽  
Author(s):  
Dennis Chan ◽  
Meredith Shafto ◽  
Rogier Kievit ◽  
Fiona Matthews ◽  
Molly Spink ◽  
...  
Keyword(s):  
Cognitive Reserve ◽  
Late Life ◽  
Lifestyle Activities

scholarly journals Lifestyle activities in mid-life contribute to cognitive reserve in late-life, independent of education, occupation and late-life activities

2018 ◽  
Author(s):  
D Chan ◽  
M Shafto ◽  
RA Kievit ◽  
FE Matthews ◽  
M Spinks ◽  
...  
Keyword(s):  
Cognitive Ability ◽  
Brain Structure ◽  
Cognitive Reserve ◽  
Late Life ◽  
Grey Matter Volume ◽  
Unique Contribution ◽  
Social Activities ◽  
Dementia Prevention ◽  
Health Initiatives ◽  
Lifestyle Activities

AbstractIntroductionThis study tested the hypothesis that mid-life intellectual, physical and social activities contribute to cognitive reserve (CR).Methods205 individuals (196 with MRI) aged 66-88 from the Cambridge Centre for Ageing and Neuroscience (www.cam-can.com) were studied, with cognitive ability and structural brain health measured as fluid IQ and total grey matter volume, respectively. Mid-life activities were measured using the Lifetime of Experiences Questionnaire.ResultsMultivariable linear regression found that mid-life activities (MA) made a unique contribution to late-life cognitive ability independent of education, occupation and late-life activities. Crucially, MA moderated the relationship between late-life cognitive ability and brain structure, with the cognitive ability of people with higher MA less dependent on their brain structure, consistent with the concept of CR.Conclusions. Mid-life intellectual, physical and social activities contribute uniquely to CR. The modifiability of these activities has implications for public health initiatives aimed at dementia prevention.

scholarly journals Idea Density Measured in Late Life Predicts Subsequent Cognitive Trajectories: Implications for the Measurement of Cognitive Reserve

2012 ◽  
Vol 67 (6) ◽  
pp. 677-686 ◽  
Author(s):  
S. T. Farias ◽  
V. Chand ◽  
L. Bonnici ◽  
K. Baynes ◽  
D. Harvey ◽  
...  
Keyword(s):  
Cognitive Reserve ◽  
Late Life

scholarly journals THE COGNITIVE RESERVE PARADOX: COGNITIVE ENGAGEMENT IN MIDLIFE PREDICTS MORE RAPID COGNITIVE DECLINE IN LATE LIFE

2018 ◽  
Vol 2 (suppl_1) ◽  
pp. 253-253
Author(s):  
J Hyun ◽  
M Sliwinski ◽  
M Katz ◽  
M Zimmerman ◽  
C Derby ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Cognitive Reserve ◽  
Cognitive Engagement ◽  
Late Life ◽  
Rapid Cognitive Decline

scholarly journals Grit in adolescence is protective of late-life cognition: non-cognitive factors and cognitive reserve

2016 ◽  
Vol 24 (3) ◽  
pp. 321-332 ◽  
Author(s):  
Emma Rhodes ◽  
Kathryn N. Devlin ◽  
Laurence Steinberg ◽  
Tania Giovannetti
Keyword(s):  
Cognitive Reserve ◽  
Late Life ◽  
Cognitive Factors

scholarly journals Cognitive reserve-mediated neural modulation of emotional control and regulation in people with late-life depression

2019 ◽  
Vol 14 (8) ◽  
pp. 849-860 ◽  
Author(s):  
Chih-Mao Huang ◽  
Yang-Teng Fan ◽  
Shwu-Hua Lee ◽  
Ho-Ling Liu ◽  
Yao-Liang Chen ◽  
...  
Keyword(s):  
Older People ◽  
Neural Activity ◽  
Emotional Regulation ◽  
Verbal Fluency ◽  
Cognitive Reserve ◽  
Protective Factor ◽  
Late Life ◽  
Aging Brain ◽  
Depression Severity ◽  
Late Life Depression

Abstract Late-life depression (LLD) is an affective disorder that is highly prevalent among older people. Cognitive reserve (CR) refers to an active process that facilitates the flexibility and efficiency of the neural networks to compensate for impairments that emerge in consequence of brain pathology. The current functional magnetic resonance imaging study investigated whether and how CR affects emotional regulation, level of depression severity and neural activity associated with affective control during emotional Stroop (eStroop) task. Altogether, 90 older people participated in this study, 50 of whom suffered from LLD. We used years of education and verbal fluency capacity as proxies for CR. Clinical participants with relatively higher CR presented with milder degrees of depression, better eStroop performance and stronger neural activity in the middle frontal gyrus (MFG) involved with exercising affective control. Results of the mediation analysis indicated that both education and verbal fluency significantly mediated the association between the depression severity and MEG activity. These results suggest a negative association between CR and age-related clinical symptoms of emotional dysregulation. Our neurobehavioral findings provide supportive evidence that CR implies efficiency of top-down emotional regulation and operates as a protective factor against emotional and cognitive vulnerability in the aging brain.

USING RACIAL/ETHNIC COMPARISONS TO EVALUATE UNMEASURED CONFOUNDING: CHILDHOOD DISADVANTAGE AND COGNITIVE RESERVE IN LATE LIFE IN THE MULTI-ETHNIC KHANDLE COHORT

2019 ◽  
Vol 15 (7) ◽  
pp. P189-P190
Author(s):  
Maria Glymour ◽  
Paola Gilsanz ◽  
Sunita Miles ◽  
Chloe W. Eng ◽  
Charles P. Quesenberry ◽  
...  
Keyword(s):  
Cognitive Reserve ◽  
Late Life ◽  
Unmeasured Confounding ◽  
Ethnic Comparisons ◽  
Childhood Disadvantage ◽  
Racial Ethnic

scholarly journals Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life

2019 ◽  
Vol 68 (2) ◽  
pp. 517-521
Author(s):  
Andreea M. Rawlings ◽  
A. Richey Sharrett ◽  
Thomas H. Mosley ◽  
Dean F. Wong ◽  
David S. Knopman ◽  
...  
Keyword(s):  
Cognitive Reserve ◽  
Amyloid Β ◽  
Late Life
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