The generation of rhythms within a cortical region: Analysis of a neural mass model

NeuroImage ◽  
2010 ◽  
Vol 52 (3) ◽  
pp. 1080-1094 ◽  
Author(s):  
Mauro Ursino ◽  
Filippo Cona ◽  
Melissa Zavaglia
2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
M. Zavaglia ◽  
F. Cona ◽  
M. Ursino

An original neural mass model of a cortical region has been used to investigate the origin of EEG rhythms. The model consists of four interconnected neural populations: pyramidal cells, excitatory interneurons and inhibitory interneurons with slow and fast synaptic kinetics, and respectively. A new aspect, not present in previous versions, consists in the inclusion of a self-loop among interneurons. The connectivity parameters among neural populations have been changed in order to reproduce different EEG rhythms. Moreover, two cortical regions have been connected by using different typologies of long range connections. Results show that the model of a single cortical region is able to simulate the occurrence of multiple power spectral density (PSD) peaks; in particular the new inhibitory loop seems to have a critical role in the activation in gamma () band, in agreement with experimental studies. Moreover the effect of different kinds of connections between two regions has been investigated, suggesting that long range connections toward interneurons have a major impact than connections toward pyramidal cells. The model can be of value to gain a deeper insight into mechanisms involved in the generation of rhythms and to provide better understanding of cortical EEG spectra.


2021 ◽  
Author(s):  
Áine Byrne ◽  
James Ross ◽  
Rachel Nicks ◽  
Stephen Coombes

AbstractNeural mass models have been used since the 1970s to model the coarse-grained activity of large populations of neurons. They have proven especially fruitful for understanding brain rhythms. However, although motivated by neurobiological considerations they are phenomenological in nature, and cannot hope to recreate some of the rich repertoire of responses seen in real neuronal tissue. Here we consider a simple spiking neuron network model that has recently been shown to admit an exact mean-field description for both synaptic and gap-junction interactions. The mean-field model takes a similar form to a standard neural mass model, with an additional dynamical equation to describe the evolution of within-population synchrony. As well as reviewing the origins of this next generation mass model we discuss its extension to describe an idealised spatially extended planar cortex. To emphasise the usefulness of this model for EEG/MEG modelling we show how it can be used to uncover the role of local gap-junction coupling in shaping large scale synaptic waves.


2016 ◽  
Vol 26 (11) ◽  
pp. 113118 ◽  
Author(s):  
Yuzhen Cao ◽  
Liu Jin ◽  
Fei Su ◽  
Jiang Wang ◽  
Bin Deng

Author(s):  
Sheikh Md. Rabiul Islam ◽  
◽  
Md. Shakibul Islam ◽  

The electroencephalogram (EEG) is an electrophysiological monitoring strategy that records the spontaneous electrical movement of the brain coming about from ionic current inside the neurons of the brain. The importance of the EEG signal is mainly the diagnosis of different mental and brain neurodegenerative diseases and different abnormalities like seizure disorder, encephalopathy, dementia, memory problem, sleep disorder, stroke, etc. The EEG signal is very useful for someone in case of a coma to determine the level of brain activity. So, it is very important to study EEG generation and analysis. To reduce the complexity of understanding the pathophysiological mechanism of EEG signal generation and their changes, different simulation-based EEG modeling has been developed which are based on anatomical equivalent data. In this paper, Instead of a detailed model a neural mass model has been used to implement different simulation-based EEG models for EEG signal generation which refers to the simplified and straightforward method. This paper aims to introduce obtained EEG signals of own implementation of the Lopes da Silva model, Jansen-Rit model, and Wendling model in Simulink and to compare characteristic features with real EEG signals and better understanding the EEG abnormalities especially the seizure-like signal pattern.


2019 ◽  
pp. 1-11
Author(s):  
Chen Liu ◽  
Changsong Zhou ◽  
Jiang Wang ◽  
Chris Fietkiewicz ◽  
Kenneth A. Loparo

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