Diurnal and seasonal variation of the brain serotonin system in healthy male subjects

NeuroImage ◽  
2015 ◽  
Vol 112 ◽  
pp. 225-231 ◽  
Author(s):  
Granville J. Matheson ◽  
Martin Schain ◽  
Rita Almeida ◽  
Johan Lundberg ◽  
Zsolt Cselényi ◽  
...  
Keyword(s):  
Seasonal Variation ◽  
Brain Serotonin ◽  
Healthy Male ◽  
Serotonin System ◽  
Male Subjects ◽  
The Brain

Structure and function of the brain serotonin system

1992 ◽  
Vol 72 (1) ◽  
pp. 165-229 ◽  
Author(s):  
B. L. Jacobs ◽  
E. C. Azmitia
Keyword(s):  
Structure And Function ◽  
Brain Serotonin ◽  
Serotonin System ◽  
And Function ◽  
The Brain

scholarly journals Investigation of the Brain Biodistribution of the Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitor [18F]GSK2647544 in Healthy Male Subjects

2016 ◽  
Vol 19 (1) ◽  
pp. 153-161 ◽  
Author(s):  
Mickael Huiban ◽  
Christopher Coello ◽  
Kai Wu ◽  
Yanmei Xu ◽  
Yvonne Lewis ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Healthy Male ◽  
Male Subjects ◽  
The Brain

Microsleeps are Associated with Stage-2 Sleep Spindles from Hippocampal-Temporal Network

2016 ◽  
Vol 26 (04) ◽  
pp. 1650015 ◽  
Author(s):  
Yaqub Jonmohamadi ◽  
Govinda R. Poudel ◽  
Carrie C. R. H. Innes ◽  
Richard D. Jones
Keyword(s):  
Power Analysis ◽  
Sleep Spindles ◽  
Healthy Male ◽  
Related Activity ◽  
Amplitude Profile ◽  
Stage 2 Sleep ◽  
Complete Disruption ◽  
Eye Closure ◽  
Male Subjects ◽  
The Brain

Behavioral microsleeps are associated with complete disruption of responsiveness for [Formula: see text][Formula: see text]s to 15[Formula: see text]s. They can result in injury or death, especially in transport and military sectors. In this study, EEGs were obtained from five nonsleep-deprived healthy male subjects performing a 1[Formula: see text]h 2D tracking task. Microsleeps were detected in all subjects. Microsleep-related activities in the EEG were detected, characterized, separated from eye closure-related activity, and, via source-space-independent component analysis and power analysis, the associated sources were localized in the brain. Microsleeps were often, but not always, found to be associated with strong alpha-band spindles originating bilaterally from the anterior temporal gyri and hippocampi. Similarly, theta-related activity was identified as originating bilaterally from the frontal-orbital cortex. The alpha spindles were similar to sleep spindles in terms of frequency, duration, and amplitude-profile, indicating that microsleeps are equivalent to brief instances of Stage-2 sleep.

scholarly journals The Relationships between Thyroid Hormones and the Brain Serotonin (5-HT) System and Mood: Of Synergy and Significance in the Adult Brain- A Review

2015 ◽  
Vol 9 (2) ◽  
pp. 98-101 ◽  
Author(s):  
Md Hafizur Rahman ◽  
Md Yusuf Ali
Keyword(s):  
Thyroid Hormones ◽  
Animal Studies ◽  
Adult Brain ◽  
Brain Serotonin ◽  
Adjunct Treatment ◽  
Serotonin System ◽  
Neuroendocrine Challenge ◽  
The Relationship ◽  
The Brain ◽  
Effective Adjunct

The use of thyroid hormones as an effective adjunct treatment for affective disorders has been studied over the past three decades and has been conformed repeatedly. Interaction of the thyroid and monoamine neurotransmitter systems has been suggested as a potential underline mechanism of action. While catecholamine and thyroid interrelationships have been reviewed in detail, the serotonin system has been relatively neglected. Thus, the goal of this article is to review the literature on the relationship between thyroid hormones and the brain serotonin (5-HT) system. In humans, neuroendocrine challenge studies in hypothyroid patients have shown a reduced 5-HT responsiveness that is reversible with replacement therapy. In the majority of the studies, the effects of thyroid hormone administration in animals will experimentally-induced hypothyroid sates include an increase in cortical 5-HT concentrations and a desensitization of auto inhibitory 5-HT1A receptors in the rap he area, resulting in disinhibition of cortical hippocampal 5-HT release. Furthermore, there is some indication that thyroid hormones may increase cortical 5-HT2 receptor sensitivity. In conclusion, there is robust evidence, particularly from animal studies, that the thyroid economy has a modulating impact in the brain serotonin system. Thus it is postulated that one mechanism, among others, through which exogenous thyroid hormones may exert their modulatory effects in affective illness is via an increase in serotonergic neurotransmission, specifically by reducing the sensitivity of 5- HT1A auto receptors in the raphe area, and by increasing 5--HT2 receptor sensitivity.Faridpur Med. Coll. J. 2014;9(2): 98-101

Imaging of the brain serotonin system

1996 ◽  
Vol 6 ◽  
pp. 165 ◽  
Author(s):  
T. Suhara ◽  
Y. Sudo ◽  
H. Fukuda ◽  
Y. Okubo ◽  
O. Inoue ◽  
...  
Keyword(s):  
Brain Serotonin ◽  
Serotonin System ◽  
The Brain

Effect of brain-derived neurotrophic factor on behavior and key members of the brain serotonin system in genetically predisposed to behavioral disorders mouse strains

Neuroscience ◽  
2012 ◽  
Vol 214 ◽  
pp. 59-67 ◽  
Author(s):  
V.S. Naumenko ◽  
E.M. Kondaurova ◽  
D.V. Bazovkina ◽  
A.S. Tsybko ◽  
M.A. Tikhonova ◽  
...  
Keyword(s):  
Behavioral Disorders ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Brain Serotonin ◽  
Mouse Strains ◽  
Serotonin System ◽  
The Brain

Effect of chronic activation of 5-HT3 receptors on 5-HT3, 5-HT1A and 5-HT2A receptors functional activity and expression of key genes of the brain serotonin system

2012 ◽  
Vol 522 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Elena M. Kondaurova ◽  
Vladimir S. Naumenko ◽  
Nina K. Popova
Keyword(s):  
Functional Activity ◽  
Brain Serotonin ◽  
Serotonin System ◽  
Chronic Activation ◽  
Key Genes ◽  
The Brain

scholarly journals Effect of cerebral dopamine neurotrophic factor (CDNF) on the behavior and expression of the key genes of the brain serotonin system in C57Bl6/J mice

IBRO Reports ◽  
2019 ◽  
Vol 6 ◽  
pp. S58
Author(s):  
Dmitriy Eremin ◽  
Tatiana Ilchibaeva ◽  
Nikita Khotskin ◽  
Vladimir Naumenko ◽  
Anton Tsybko
Keyword(s):  
Neurotrophic Factor ◽  
Brain Serotonin ◽  
Serotonin System ◽  
Cerebral Dopamine Neurotrophic Factor ◽  
Key Genes ◽  
The Brain ◽  
Cerebral Dopamine
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