scholarly journals Focal fMRI signal enhancement with implantable inductively coupled detectors

NeuroImage ◽  
2021 ◽  
pp. 118793
Author(s):  
Yi Chen ◽  
Sangcheon Choi ◽  
Hang Zeng ◽  
Kengo Takahashi ◽  
Chunqi Qian ◽  
...  
Keyword(s):  
Signal Enhancement ◽  
Inductively Coupled ◽  
Fmri Signal

scholarly journals Focal fMRI signal enhancement with implantable inductively coupled detectors

2021 ◽  
Author(s):  
Yi Chen ◽  
Qi Wang ◽  
Sangcheon Choi ◽  
Hang Zeng ◽  
Kengo Takahashi ◽  
...  
Keyword(s):  
Signal To Noise Ratio ◽  
Signal Enhancement ◽  
Limiting Factor ◽  
Spatiotemporal Resolution ◽  
Inductively Coupled ◽  
Fmri Signal ◽  
Functional Dynamics ◽  
Technical Advances ◽  
Brain Interface ◽  
Cortical Regions

Despite extensive efforts to increase the signal-to-noise ratio (SNR) of fMRI images for brain-wide mapping, technical advances of focal brain signal enhancement are lacking, in particular, for animal brain imaging. Emerging studies have combined fMRI with fiber optic-based optogenetics to decipher circuit-specific neuromodulation from meso to macroscales. Acquiring fMRI signal with high spatiotemporal resolution is needed to bridge cross-scale functional dynamics, but SNR of targeted cortical regions is a limiting factor. We have developed a multi-modal fMRI imaging platform with an implanted inductive coil detector. This detector boosts the tSNR of MRI images, showing a 2-3 fold sensitivity gain over conventional coil configuration. In contrast to the cryoprobe or array coils with limited spaces for implanted brain interface, this setup offers a unique advantage to study brain circuit connectivity with optogenetic stimulation and can be further extended to other multi-modal fMRI mapping schemes.

Signal enhancement of elements due to the presence of carbon-containing compounds in inductively coupled plasma mass spectrometry

1991 ◽  
Vol 63 (14) ◽  
pp. 1497-1498 ◽  
Author(s):  
Pierre. Allain ◽  
Laurent. Jaunault ◽  
Yves. Mauras ◽  
Jean Michel. Mermet ◽  
Thierry. Delaporte
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Signal Enhancement ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

Signal enhancement and reduction of interferences in inductively coupled plasma mass spectrometry with an argon–trifluoromethane mixed aerosol carrier gas

1994 ◽  
Vol 9 (6) ◽  
pp. 719-726 ◽  
Author(s):  
Isaac Platzner ◽  
José V. Sala ◽  
Francis Mousty ◽  
Pier R. Trincherini ◽  
Alberto L. Polettini
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Signal Enhancement ◽  
Carrier Gas ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

Study on carbon-induced signal enhancement in inductively coupled plasma mass spectrometry: an approach from the spatial distribution of analyte signal intensities

2019 ◽  
Vol 34 (9) ◽  
pp. 1865-1874 ◽  
Author(s):  
Tomoko Ariga ◽  
Yanbei Zhu ◽  
Kazumi Inagaki
Keyword(s):  
Spatial Distribution ◽  
Inductively Coupled Plasma ◽  
Signal Enhancement ◽  
Inductively Coupled ◽  
Analyte Signal ◽  
Novel Approach ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Induced Signal ◽  
Signal Intensities

This study proposed a novel approach for quantifying carbon-induced signal enhancement in ICP-MS considering the spatial distribution of analyte signal intensities.

Signal enhancement in laser ablation inductively coupled plasma-mass spectrometry using water and/or ethanol vapor in combination with a shielded torch

2014 ◽  
Vol 29 (3) ◽  
pp. 536 ◽  
Author(s):  
Shenghua Liu ◽  
Zhaochu Hu ◽  
Detlef Günther ◽  
Yonghao Ye ◽  
Yongsheng Liu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Laser Ablation ◽  
Inductively Coupled Plasma ◽  
Ethanol Vapor ◽  
Signal Enhancement ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

Application of inductively coupled plasma mass spectrometry in the study of apoptosis: determination of caspase-3 using a gold nanoparticle tag

The Analyst ◽  
2016 ◽  
Vol 141 (3) ◽  
pp. 926-933 ◽  
Author(s):  
Zhengru Liu ◽  
Beibei Chen ◽  
Man He ◽  
Xing Zhang ◽  
Han Wang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gold Nanoparticle ◽  
Inductively Coupled Plasma ◽  
Caspase 3 ◽  
Signal Enhancement ◽  
Secondary Antibody ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

A simple, fast and sensitive immunoassay for caspase-3 is established by using inductively coupled plasma mass spectrometry (ICP-MS) detection and signal enhancement gold nanoparticle (Au-NP) labelling of the secondary antibody (IgG).

In contrast to BOLD: signal enhancement by extravascular water protons as an alternative mechanism of endogenous fMRI signal change

2010 ◽  
Vol 28 (8) ◽  
pp. 1234-1243 ◽  
Author(s):  
Chase R. Figley ◽  
Jordan K. Leitch ◽  
Patrick W. Stroman
Keyword(s):  
Signal Enhancement ◽  
Alternative Mechanism ◽  
Bold Signal ◽  
Fmri Signal ◽  
Signal Change

scholarly journals Comparison of signal enhancement by co-existing carbon and by co-existing bromine in inductively coupled plasma mass spectrometry

2014 ◽  
Vol 29 (7) ◽  
pp. 1299-1305 ◽  
Author(s):  
Takashi Nakazawa ◽  
Daisuke Suzuki ◽  
Hironori Sakuma ◽  
Naoki Furuta
Keyword(s):  
Mass Spectrometry ◽  
Ionization Energy ◽  
Inductively Coupled Plasma ◽  
Signal Enhancement ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

Co-existing bromine did not enhance the signals of analytes, even though the ionization energy is similar to that of carbon.

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