Neonatal exposure to ketamine disrupts developmental synapse unsilencing and predisposes adult mice for stressor-evoked anxiety

2020 ◽  
Vol 180 ◽  
pp. 108300
Author(s):  
Xiaoyun Zhang ◽  
Yue Kong ◽  
Guiqin He ◽  
Zikai Zhou
Keyword(s):  
1991 ◽  
Vol 7 (1) ◽  
pp. 63-69 ◽  
Author(s):  
E. Pailhoux ◽  
A. Martinez ◽  
Ch. Jean-Faucher ◽  
G. Veyssière ◽  
Cl. Jean

ABSTRACT We have previously characterized an androgen-inducible secretory protein from the mouse vas deferens (MVDP), and a cDNA to its mRNA has been obtained. This report describes altered MVDP gene expression after neonatal exposure to oestrogens. As shown by immunohistochemistry and Western blot analysis, MVDP was missing in the vas deferens from adult mice neonatally exposed to oestrogens. Northern blot analysis showed that the expression of MVDP mRNA was also suppressed. Exogenous testosterone was unable to stimulate MVDP production (either message or protein) in neonatally oestrogenized males. The results suggest that the alterations in gene expression in the oestrogen-exposed vas deferens reflect changes in the programme of differentiation of the organ itself.


1996 ◽  
Vol 10 (3) ◽  
pp. 235-248 ◽  
Author(s):  
Adriana del Rey ◽  
Hiromu Furukawa ◽  
Gabriela Monge-Arditi ◽  
Alexa Kabiersch ◽  
Karl-Heinz Voigt ◽  
...  

2001 ◽  
Vol 48 (6) ◽  
pp. 655-663 ◽  
Author(s):  
TAKAKO SHIBAYAMA ◽  
HIDEKI FUKATA ◽  
KENICHI SAKURAI ◽  
TETSUYA ADACHI ◽  
MASATOSHI KOMIYAMA ◽  
...  

2014 ◽  
Vol 297 (4) ◽  
pp. 758-769 ◽  
Author(s):  
Megan O'Reilly ◽  
Philip M. Hansbro ◽  
Jay C. Horvat ◽  
Emma L. Beckett ◽  
Richard Harding ◽  
...  
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