scholarly journals Within amygdala: basolateral parts are selectively impaired in premature-born adults

2021 ◽  
pp. 102780
Author(s):  
Benita Schmitz-Koep ◽  
Juliana Zimmermann ◽  
Aurore Menegaux ◽  
Rachel Nuttall ◽  
Josef G. Bäuml ◽  
...  
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2020 ◽  
Vol 9 (1) ◽  
pp. 1-5
Author(s):  
Jatinder Singh ◽  
Vaneeta Bhardwar ◽  
Harshdhawann Singh ◽  
Isha Bhardwaj ◽  
Sushmita Choudhary ◽  
...  

2021 ◽  
Vol 13 ◽  
Author(s):  
Dennis M. Hedderich ◽  
Aurore Menegaux ◽  
Benita Schmitz-Koep ◽  
Rachel Nuttall ◽  
Juliana Zimmermann ◽  
...  

Recent evidence suggests increased metabolic and physiologic aging rates in premature-born adults. While the lasting consequences of premature birth on human brain development are known, its impact on brain aging remains unclear. We addressed the question of whether premature birth impacts brain age gap estimates (BrainAGE) using an accurate and robust machine-learning framework based on structural MRI in a large cohort of young premature-born adults (n = 101) and full-term (FT) controls (n = 111). Study participants are part of a geographically defined population study of premature-born individuals, which have been followed longitudinally from birth until young adulthood. We investigated the association between BrainAGE scores and perinatal variables as well as with outcomes of physical (total intracranial volume, TIV) and cognitive development (full-scale IQ, FS-IQ). We found increased BrainAGE in premature-born adults [median (interquartile range) = 1.4 (−1.3–4.7 years)] compared to full-term controls (p = 0.002, Cohen’s d = 0.443), which was associated with low Gestational age (GA), low birth weight (BW), and increased neonatal treatment intensity but not with TIV or FS-IQ. In conclusion, results demonstrate elevated BrainAGE in premature-born adults, suggesting an increased risk for accelerated brain aging in human prematurity.


2016 ◽  
Vol 127 (2) ◽  
pp. 1216-1222 ◽  
Author(s):  
Ravi Poorun ◽  
Caroline Hartley ◽  
Sezgi Goksan ◽  
Alan Worley ◽  
Stewart Boyd ◽  
...  

2018 ◽  
Vol 39 (12) ◽  
pp. 4903-4912 ◽  
Author(s):  
Jing Shang ◽  
Josef G. Bäuml ◽  
Nikolaos Koutsouleris ◽  
Marcel Daamen ◽  
Nicole Baumann ◽  
...  
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2019 ◽  
Vol 31 (4) ◽  
pp. 829-833
Author(s):  
Olga Kokoceva-Ivanovskа ◽  
Efka Zabokova-Bilbilovska ◽  
Aneta Mijoska

In everyday dental practice, because of the incorrect diet and the absence of oral hygiene in the earliest childhood age, we increasingly face the problem of diagnosing circular cavities in the advanced developmental phase. The aim of the research was to show whether the diseases and complications which occur during the pregnancy period of the mother, and the child’s health condition immediately after the birth, affect the appearance and predisposition of the circular caries. Our examines were children 2-3 years old, where during the standard check-ups we diagnosed starting phases of circular caries-initial lesion (white spot) and superficial form. A questionnaire prepared in advance was given to the mothers of the children diagnosed with circular caries, where we inserted the data for the period of pregnancy (pathologic pregnancy, premature birth with complications and normal pregnancy without any complications) as well as the diseases of the children during the first year of their life (bronchitis, pneumonias, infective diseases). After elaborating the data from the questionnaire, we got the number of 28.21% mothers who had pathological pregnancy and 18.80% had premature birth accompanied with complications. In the first year of the age 35.38% of the children had bronchitis, pneumonias and very often 10% infective diseases. The analysis of the results showed that the circular caries so called early childhood caries is present more often at children whose mothers had pathological pregnancy, premature born children and children who were often ill during the first year of age. These results prove that the fact that problematic pregnancy and the child’s state of health immediately after the birth are factors of predisposition to the appearance of the early childhood caries.


2020 ◽  
Vol 41 (18) ◽  
pp. 5215-5227
Author(s):  
Dennis M. Hedderich ◽  
Mihai Avram ◽  
Aurore Menegaux ◽  
Rachel Nuttall ◽  
Juliana Zimmermann ◽  
...  
Keyword(s):  

Author(s):  
Merete S. Engeseth ◽  
Ola D. Røksund ◽  
Maria Vollsæter ◽  
Thomas Halvorsen ◽  
Hege H. Clemm

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