S-Nitrosoglutathione incorporated in poly(ethylene glycol) matrix: potential use for topical nitric oxide delivery

Nitric Oxide ◽  
2004 ◽  
Vol 11 (3) ◽  
pp. 263-272 ◽  
Author(s):  
Amedea Barozzi Seabra ◽  
Gabriela Freitas Pereira de Souza ◽  
Lilian Lúcia da Rocha ◽  
Marcos Nogueira Eberlin ◽  
Marcelo Ganzarolli de Oliveira
Keyword(s):  
Nitric Oxide ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Matrix Potential ◽  
Poly Ethylene ◽  
Nitric Oxide Delivery ◽  
Potential Use

Encapsulation of hemoglobin inside liposomes surface conjugated with poly(ethylene glycol) attenuates their reactions with gaseous ligands and regulates nitric oxide dependent vasodilation

2012 ◽  
Vol 28 (3) ◽  
pp. 636-645 ◽  
Author(s):  
Shahid Rameez ◽  
Nicole Guzman ◽  
Uddyalok Banerjee ◽  
Jorge Fontes ◽  
Michael E. Paulaitis ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings

2017 ◽  
Vol 105 (12) ◽  
pp. 3360-3368 ◽  
Author(s):  
Julia Koehler ◽  
Leonie Verheyen ◽  
Sarah Hedtrich ◽  
Ferdinand P. Brandl ◽  
Achim M. Goepferich
Keyword(s):  
Ethylene Glycol ◽  
Wound Dressings ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Potential Use

Nitric oxide-releasing polymeric furoxan conjugates

2015 ◽  
Vol 6 (44) ◽  
pp. 7737-7748 ◽  
Author(s):  
Tengjiao Wang ◽  
André J. van der Vlies ◽  
Hiroshi Uyama ◽  
Urara Hasegawa
Keyword(s):  
Nitric Oxide ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
No Donors ◽  
Poly Ethylene ◽  
Nitric Oxide Releasing ◽  
End Group

Polymeric nitric oxide (NO) donors were prepared by the conjugation of the azide-containing furoxans and poly(ethylene glycol) having an alkyne end groupviathe copper-catalyzed Huisgen cycloaddition.

scholarly journals Effect of Molecular Weight on Gelling and Viscoelastic Properties of Poly(caprolactone)–b-Poly(ethylene glycol)–b-Poly(caprolactone) (PCL–PEG–PCL) Hydrogels

Polymers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2372
Author(s):  
Noam Y. Steinman ◽  
Noam Y. Bentolila ◽  
Abraham J. Domb
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
Mechanical Strength ◽  
High Viscosity ◽  
Poly Ethylene Glycol ◽  
Simple Modification ◽  
Poly Ethylene ◽  
Poly Caprolactone ◽  
Injectable Fillers ◽  
Potential Use

Hydrogels based on poly(caprolactone)–b-poly(ethylene glycol)–b-poly(caprolactone) (PCL–PEG–PCL) have been evaluated extensively as potential injectable fillers or depots for controlled release of drugs. Common drawbacks of these copolymer systems include instability of aqueous solutions and low mechanical strength of gels, issues which are commonly overcome by adding pendant groups to the end of the copolymer chains. Here, a systematic study of the effects of increasing polymer molecular weight (MW) is presented, utilizing PEG blocks of MW 2, 4 or 8 kDa. Triblock copolymers were prepared by the ring-opening polymerization of Ɛ-caprolactone by PEG. Copolymers prepared with PEG MW 2 kDa did not form hydrogels at any copolymer molecular weight. Copolymers prepared with PEG MW 4 kDa formed gels at MW between 11 and 13.5 kDa, and copolymers prepared with PEG MW 8 kDa formed gels at MW between 16 and 18 kDa. Copolymers with PEG block 8 kDa formed hydrogels with high viscosity (17,000 Pa·s) and mechanical strength (G′ = 14,000 Pa). The increased gel strength afforded by increased molecular weight represents a simple modification of the reactants used in the reaction feed without added synthetic or purification steps. Shear-thinning of PCL-PEG-PCL triblock copolymer hydrogels allowed for injection through a standard 23G syringe, allowing for potential use as dermal fillers or drug delivery depots.

Nitric Oxide Gas Delivery by Fluorinated Poly(Ethylene Glycol)@Graphene Oxide Carrier toward Pharmacotherapeutics

2019 ◽  
Vol 5 (6) ◽  
pp. 2926-2934 ◽  
Author(s):  
Yitayal Admassu Workie ◽  
Sabrina ◽  
Toyoko Imae ◽  
Marie Pierre Krafft
Keyword(s):  
Nitric Oxide ◽  
Graphene Oxide ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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