scholarly journals The histone H3 lysine 9 methyltransferase G9a/GLP complex activity is required for long-term consolidation of spatial memory in mice

2021 ◽  
Vol 179 ◽  
pp. 107406
Author(s):  
Kyrian Nicolay-Kritter ◽  
Jordan Lassalle ◽  
Jean-Louis Guillou ◽  
Nicole Mons
Keyword(s):  
Spatial Memory ◽  
Histone H3 ◽  
Complex Activity

scholarly journals Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Javier Díaz-Alonso ◽  
Wade Morishita ◽  
Salvatore Incontro ◽  
Jeffrey Simms ◽  
Julia Holtzman ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Morris Water Maze ◽  
Ampa Receptor ◽  
Water Maze ◽  
Long Term Potentiation ◽  
Receptor Subunit ◽  
Terminal Domain ◽  
Term Potentiation ◽  
Ampa Receptor Subunit

We tested the proposal that the C-terminal domain (CTD) of the AMPAR subunit GluA1 is required for LTP. We found that a knock-in mouse lacking the CTD of GluA1 expresses normal LTP and spatial memory, assayed by the Morris water maze. Our results support a model in which LTP generates synaptic slots, which capture passively diffusing AMPARs.

scholarly journals Bell-Shaped D-Serine Actions on Hippocampal Long-Term Depression and Spatial Memory Retrieval

2008 ◽  
Vol 18 (10) ◽  
pp. 2391-2401 ◽  
Author(s):  
Z. Zhang ◽  
N. Gong ◽  
W. Wang ◽  
L. Xu ◽  
T.-L. Xu
Keyword(s):  
Spatial Memory ◽  
Memory Retrieval ◽  
Long Term Depression

Postnatal exposure to chlorpyrifos produces long-term effects on spatial memory and the cholinergic system in mice in a sex- and APOE genotype-dependent manner

2018 ◽  
Vol 122 ◽  
pp. 1-10 ◽  
Author(s):  
Laia Guardia-Escote ◽  
Pia Basaure ◽  
Jordi Blanco ◽  
Maria Cabré ◽  
Cristian Pérez-Fernández ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Cholinergic System ◽  
Apoe Genotype ◽  
Dependent Manner ◽  
Postnatal Exposure ◽  
Long Term Effects
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