ABSTRACT
Cancer is a complex disease that is variable in its presentation, development and outcome. The same heterogeneity and variability exist at the cellular and molecular level. Cancer is a multistep process during which cells undergo intense metabolic and behavioral changes, leading them to proliferate in an extreme and early way to escape supervision by the immune system and ultimately invades distant tissues to form metastases. Globally, almost 20% of cancers are related to infectious agents. Several viruses with oncogenic potential stimulate cell proliferation leading to cancer in animals and humans. Viruses, in particular, have been found to play a major role in the process of cancer involving several organs. Bacterial species related with cancer etiology are varied; however, the infections they cause have common characteristics. The association between Helicobacter pylori and gastric carcinoma is well established but the association between H. pylori and oral squamous cell carcinoma (OSCC) is not evident. Studies have also reported the existence of H. pylori in the oral cavity, but whether the oral cavity serves as an extra gastric source for H. pylori or carries the organism only transiently is debatable. Hence, with this aim in the mind, we conducted the present study to evaluate the incidence of H. pylori in premalignant disorders and OSCC.
How to cite this article
Sharma P, Gawande M, Chaudhary M. Evaluation of Prevalence of Bacteria Helicobacter pylori in Potentially Malignant Disorders and Oral Squamous Cell Carcinoma. World J Dent 2015;6(2):82-86.
Evaluation of Prevalence of Bacteria Helicobacter pylori in Potentially Malignant Disorders and Oral Squamous Cell Carcinoma
