COCAINE-INDUCED MIDLINE DESTRUCTIVE LESION WITH NASAL AND ORAL INVOLVEMENT: A CASE REPORT

Author(s):  
DAMILYS JOELLY SOUZA SANTOS ◽  
VINÍCIUS GONÇALVES DE SOUZA ◽  
THALÍA RISSA SILVA ◽  
EDUARDO CARREIRA MARCÓRIO ◽  
APARECIDA DE LOURDES CARVALHO ◽  
...  
Keyword(s):  
2021 ◽  
Vol 6 (1) ◽  
pp. 79
Author(s):  
Etis Duhita Rahayuningtyas ◽  
Indah Suasani Wahyuni ◽  
Irna Sufiawati

ABSTRACTBackground: Stevens-Johnson syndrome (SSJ) is a hypersensitivity reaction that is often triggered by drugs but this case is rare. These reactions result in uncontrolled keratinocyte damage to the skin and mucosa throughout the body, including the oral mucosa, and are often life-threatening. The use of high doses of corticosteroids is a treatment that is often given but it can trigger secondary infections of fungal and viral in the oral cavity. Purpose: This case report discusses the management of oral manifestations and secondary infections in SSJ patients, and becomes guidance for health professionals. Case: A-42-years-old male patient was consulted from the Department of Dermatology and Venereology (DV) due to oral pain and eating difficulties. The severity-of-illness-score for toxic-epidermal-necrolysis (SCORTEN) was 1. Erosive serosanguinous crusts, tend to bleed were found on the lips. Intraoral clinically presented wide erosive lesions and multiple ulcers, accompanied by a pseudomembranous plaque, and teeth decay. Hematologic examination showed an increase in leukocytes, neutrophil segments, monocytes, SGOT, urea, and creatinine as well as decreased hemoglobin, hematocrit, erythrocytes, MCHC, protein, and albumin. Anti-HSV1 IgG increased almost 6 times than normal values. The patient was diagnosed with SJS with oral involvement, secondary infections of pseudomembranous candidiasis, and herpetic stomatitis. Case Management: Systemic therapy given were intravenous dexamethasone, ranitidine, calcium, and cetirizine, from the DV Department, while hydrocortisone lip ointment, Chlorhexidine digluconate 0.12%, and Nystatin oral suspension for oral problems. The lesions progressed in 24 days. Conclusion: Oral secondary infections may occur in SJS patients due to high-dose corticosteroid therapy.Keywords: Herpetic Stomatitis, Oral Manifestation, Oral Secondary Infection, Pseudomembranous Candidiasis, Stevens-Johnson Syndrome.


2010 ◽  
Vol 2 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Geetha Paramkusam ◽  
Venkateswarlu Meduri ◽  
Naresh Gangeshetty

2010 ◽  
Vol 4 (1) ◽  
Author(s):  
M İnanç Cengiz ◽  
Hom-Lay Wang ◽  
Levent Yıldız

2019 ◽  
Vol 12 (04) ◽  
pp. 2123-2132
Author(s):  
Sura Ali Ahmed Fuoad ◽  
Fadia Michel Kusairy ◽  
Walid Shabban Al-Sayed ◽  
Prabhu M. N. ◽  
Pooja Narain Adtani

One of the commonly encountered lesions in oral cavity is oral ulceration. They arise from various etiology, being associated with discomfort or pain, rarely results in complications and scarring. The nonspecific clinical presentation of oral ulceration in the oral cavity, will made their diagnosis crucial, however a detailed patient history, comprehensive clinical examination together with background knowledge of possible causes will lead to correct diagnosis and subsequent treatment, moreover distinguishing between erythema multiforme (EM) and herpes simples viral infection (HSV) when there is only oral involvement is of a great importance as the treatment of EM is contra indicated for HSV.


2014 ◽  
Vol 18 (3) ◽  
pp. 157-160
Author(s):  
Dimitrios Andreadis ◽  
Athanasios K. Poulopoulos ◽  
Anthi Asimaki ◽  
Eleni Albanidou-Farmaki ◽  
Anastasios K. Markopoulos

SUMMARYBackground: Angiokeratoma is an asymptomatic, hyperkeratotic, capillary disorder of the skin present as solitary or multiple, keratotic papules or plaques, which may also be related to Fabry disease. Oral involvement may be observed in cases of widespread muco-cutaneous angiokeratomas, whereas solitary buccal angiokeratoma without systemic/cutaneous involvement is extremely rare.Case Report: A 45-year-old woman was referred with a 3-month, painless, bluish lesion, located on left buccal mucosa. The medical record of the patient was free of any systemic disease or medication. After a careful clinical oral, mucosal as well as skin examination, an excisional biopsy was taken. A routine haematoxylin-eosin staining and additional immunohistochemistry were performed. Differential diagnosis included haemangioma, haematoma or lesions of melanocytic origin. Clinical examination showed a solid, lobulated bluish lesion, located on left buccal mucosa without other skin or mucosal involvement. The microscopic findings revealed dilated vascular spaces covered by normal endothelium without atypia, extending into the epithelium, indicating the diagnosis of angiokeratoma.Conclusions: Despite its rare occurrence, solitary angiokeratoma of oral mucosa should be included in the differential diagnosis of black-bluish lesions. Further investigation for other similar lesions throughout skin or mucosa is needed to avoid complications as haemorrhage.


2004 ◽  
Vol 118 (5) ◽  
pp. 385-387 ◽  
Author(s):  
Lakshmanan Suresh ◽  
Luis Edmundo Martinez Calixto ◽  
Alfredo Aguirre ◽  
Stuart L. Fischman

Sarcoidosis is a multi-system, non-caseating granulomatous disease of unknown aetiology that may affect any organ. The oral involvement of sarcoidosis is rare and usually an initial manifestation of the disease. In this case report the authors present a 25-year-old African-American woman with palatal sarcoidosis treated successfully with intra-lesional corticosteroid injections. The oral manifestationsof sarcoidosis are relatively uncommon and may be the only manifestation of the disease. Suspected cases of oral sarcoidosis should be biopsied and subsequently referred to a physician to rule out systemic involvement.


2019 ◽  
Vol 29 (1) ◽  
pp. 57
Author(s):  
Nancy Alfieri Nunes ◽  
Ana Maria Pires Soubhia ◽  
Gabriela Lopes Dos Santos ◽  
Leonardo Ferreira de Toledo Piza Lopes

Paracoccidioidomycosis is a fungal systemic disease with involvement of the lung and buccal mucosa. Objective: A brief bibliographic survey and clinical case report. Case report: A 48-year-old male patient, former smoker, alcoholic and drug user attended the Stomatology Service Lins School of Dentistry with ulcerated lesions in the perioral and intraoral region, with painful symptomatology, weight loss, and severe cough. It was clinically evaluated with suspected paracoccidioidomycosis and underwent complementary tests, including biopsy for evidence of the yeast form of Paracoccidioides brasiliensis. Complementary exams and biopsy were conclusive for paracoccidiodoimycosis, with primary pulmonary involvement and secondary buccal mucosa involvement, being submitted to antifungal treatment with excellent result in thirty days. Conclusion: The dental surgeon must know to diagnose and treat systemic diseases with oral involvement, such as paracoccidioidomycosis, including in a multidisciplinary way, with periodic proservation of the patient, since the lesions may recur due to exacerbation of the clinical picture, drug resistance or even negligence of the patient regarding treatment and adverse drug effects. Key words: Paracocidioidomycosis; Mycoses; Pneumopathies; Oral Diseases


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