Anterior-Segment Ocular Findings and Microphthalmia in Congenital Zika Syndrome

Purpose: To describe the magnitude and spectrum of abnormal ocular findings other than retinopathy of prematurity (ROP) detected during an ROP telescreening programme. Methods: Retrospective review of the records of all premature babies screened for ROP from August 2015 to December 2019. Results: A total 9105 babies were screened during the study period with total 17,075 imaging sessions. Non-ROP ocular abnormalities were seen in 566 eyes of 383 babies (4.2%) including 207 male (54%) and 176 female babies (46%). Posterior segment abnormalities were seen in 88.2% babies (338/383) with haemorrhage being the most common (77%, 295/383). Anterior segment pathologies were seen in 12% babies (46/383) with congenital cataract being the most common pathology requiring surgical intervention. Other findings included globe abnormalities in 0.8% babies (3/383), adnexal disorders in 0.5% babies (2/383) and squint in 0.3% babies (1/383). Rare life-threatening conditions such as retinoblastoma and lipaemia retinalis were also detected. Eighty-seven babies (22.7%) were diagnosed with referral-warranted non-ROP pathologies, with an overall prevalence of 1% (87/9105). Prompt surgical intervention was advised for 7.3% babies (28/383), 3.4% babies (13/383) were treated medically and 4.2% babies (16/383) needed visual rehabilitation for non-amenable pathologies. Conclusion: This is the largest study describing the magnitude and spectrum of neonatal ocular pathologies other than ROP in a cohort of premature babies. Digital imaging has a significant impact on early detection and timely intervention for various vision as well as life-threatening non-ROP pathologies, which would have been missed or delayed otherwise.

Download Full-text

INFANTS WITH CONGENITAL ZIKA SYNDROME AND OCULAR FINDINGS FROM SÃO PAULO, BRAZIL

Retinal Cases & Brief Reports ◽

10.1097/icb.0000000000000518 ◽

2018 ◽

Vol 12 (4) ◽

pp. 382-386 ◽

Cited By ~ 11

Author(s):

João Rafael de Oliveira Dias ◽

Camila V. Ventura ◽

Paula Delegrego Borba ◽

Bruno de Paula Freitas ◽

Ligia Camera Pierroti ◽

...

Keyword(s):

Sao Paulo ◽

São Paulo ◽

Ocular Findings ◽

Congenital Zika Syndrome

Download Full-text

Prevalence of ocular findings regardless of visual acuity status in older adults from the Brazilian Amazon Region

Scientific Reports ◽

10.1038/s41598-021-03172-4 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Arthur G. Fernandes ◽

Adriana Berezovsky ◽

Sung E. S. Watanabe ◽

Márcia R. K. H. Mitsuhiro ◽

Marcela C. Cypel ◽

...

Keyword(s):

Older Adults ◽

Visual Acuity ◽

Anterior Segment ◽

Brazilian Amazon ◽

Population Based ◽

Amazon Region ◽

Ocular Findings ◽

Brazilian Amazon Region ◽

High Prevalence ◽

Ocular Finding

AbstractRecently, it has been recommended that population-based studies report not only frequencies of vision impairment and blindness but also any ocular abnormalities that might lead an individual to seek for eyecare services. The current study aimed to determine prevalence of ocular findings regardless of visual acuity (VA) status in older adults from the Brazilian Amazon Region. Disturbances were grouped into: Eyelids; Anterior Segment; Posterior Segment; Increased intraocular pressure; and Overall Globe. The presence of an ocular finding was considered positive when any abnormality was noted, regardless of VA. Refractive errors were not considered. A total 2384 eligible persons were enumerated and 2041 (85.6%) examined. The prevalence of ocular disturbances in either eye was 87.0% and was associated with male gender, older age, lower education, and rural residence. Overall, main findings were pterygium, cataract, and pinguecula, occurring in 58.8%, 45.4% and 17.4%, respectively. Among individuals with 20/20 VA in both eyes, the most frequent findings were pterygium, pinguecula, and glaucoma cupping, occurring in 47.4%, 31.2% and 6.5%, respectively. The high prevalence of ocular findings observed in this population reinforces that different conditions might not immediately decrease VA but can indicate risk and/or discomfort symptoms and should be considered when planning public health ophthalmic services.

Download Full-text

Ocular Findings in Children with Congenital Zika Syndrome

Zika in Focus ◽

10.1007/978-3-319-53643-9_4 ◽

2017 ◽

pp. 47-57

Author(s):

Camila V. Ventura ◽

Natalia C. Dias ◽

Audina M. Berrocal ◽

Liana O. Ventura

Keyword(s):

Ocular Findings ◽

Congenital Zika Syndrome

Download Full-text

Patterns of ocular inflammation in patients with miliary tuberculosis

F1000Research ◽

10.12688/f1000research.11035.1 ◽

2017 ◽

Vol 6 ◽

pp. 412

Author(s):

Salil Mehta

Keyword(s):

Anterior Segment ◽

Miliary Tuberculosis ◽

Posterior Uveitis ◽

Ocular Inflammation ◽

Slit Lamp ◽

Slit Lamp Examination ◽

Ocular Findings ◽

Intermediate Segment ◽

Ocular Morbidity ◽

Immunocompetent Patients

Background: Ocular morbidity associated with systemic tuberculosis is common. The clinical picture varies from anterior uveitis, intermediate uveitis and posterior uveitis to even panuveitis. There is little data on the correlation between specific systemic presentations and the ocular inflammation. We conducted a retrospective review of the ocular findings in the case records of patients admitted with a diagnosis of miliary tuberculosis. These patients were then referred for a more detailed ophthalmic evaluation. Methods: We analysed the case records of patients with a clinical diagnosis of miliary tuberculosis over a 10-year period at Lilavati Hospital and Research Center, Mumbai. Results: In total, 11 immunocompetent patients were identified. All 22 eyes showed normal findings on slit lamp examination. Dilated fundus examination showed single or multiple tubercles. In our cohort, the ocular findings were exclusively in the form of choroidal tuberculosis, either unilaterally or bilaterally. Slit lamp examination revealed no anterior segment inflammation Conclusions: We suggest that this pattern of choroidal/retinal tuberculosis in the absence of anterior and intermediate segment inflammation is specific for miliary tuberculosis and may be related to a specific immune response.

Download Full-text

Video Atlas of Anterior Segment Repair and Reconstruction

10.1055/b-006-163722 ◽

2019 ◽

Author(s):

Amar Agarwal ◽

Ashar Agarwal ◽

Ashvin Agarwal ◽

Athiya Agarwal ◽

Sreelakshmi P. Amar ◽

...

Keyword(s):

Anterior Segment

Download Full-text

Outcome of Buccal Mucosal Graft Urethroplasty in Long Segment Anterior Urethral Stricture

Bangladesh Journal of Urology ◽

10.3329/bju.v19i2.49365 ◽

2020 ◽

Vol 19 (2) ◽

pp. 64-68

Author(s):

Mrinmoy Biswas ◽

Sudip Das Gupta ◽

Mohammed Mizanur Rahman ◽

Sharif Mohammad Wasimuddin

Keyword(s):

Urethral Stricture ◽

Flow Rate ◽

Surgical Outcome ◽

Simple Technique ◽

Anterior Segment ◽

Maximum Flow ◽

Anastomotic Site ◽

Buccal Mucosal Graft ◽

Male Patients

Objective: To assess the success of BMG urethroplasty in long segment anterior urethral stricture. Method: From January 2014 to December 2015, twenty male patients with long anterior segment urethral stricture were managed by BMG urethroplasty. After voiding trial they were followed up at 3 month with Uroflowmetry, RGU & MCU and PVR measurement by USG. Patients were further followed up with Uroflowmetry and PVR at 6 months interval.Successful outcome was defined as normal voiding with a maximum flow rate >15ml /sec and PVR<50 ml with consideration of maximum one attempt of OIU after catheter removal. Results: Mean stricture length was 5.2 cm (range 3-9 cm) and mean follow-up was 15.55 months (range 6-23 months). Only two patients developed stricture at proximal anastomotic site during follow-up. One of them voided normally after single attempt of OIU. Other one required second attempt of OIU and was considered as failure (5%). Conclusion: BMG urethroplasty is a simple technique with good surgical outcome. Bangladesh Journal of Urology, Vol. 19, No. 2, July 2016 p.64-68

Download Full-text

Utility of the Anterior Segment Optical Coherence Tomography for Measurements of Central Corneal Thickness

Journal of the Korean Ophthalmological Society ◽

10.3341/jkos.2007.48.12.1643 ◽

2007 ◽

Vol 48 (12) ◽

pp. 1643 ◽

Cited By ~ 3

Author(s):

Hyoung Sub Shim ◽

Chul Young Choi ◽

Hee Gyung Lee ◽

Myoung Joon Kim ◽

Hung Won Tchah

Keyword(s):

Optical Coherence Tomography ◽

Central Corneal Thickness ◽

Corneal Thickness ◽

Anterior Segment ◽

Optical Coherence

Download Full-text

Pediatric Free-floating Anterior Chamber Cyst of the Iris Pigment Epithelium

American Journal of Ophthalmic Clinical Trials ◽

10.25259/ajoct-5-2018 ◽

2018 ◽

Vol 1 ◽

pp. 3

Author(s):

Joshua S Agranat ◽

Yoshihiro Yonekawa

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Incidental Finding ◽

Pigment Epithelium ◽

Anterior Segment ◽

Ultrasound Biomicroscopy ◽

Optical Coherence ◽

Visual Axis ◽

Associated Malignancy ◽

Anatomic Locations

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.

Download Full-text