The prognostic value of Mural Nodules and their size in IPMN of the Pancreas: High-volume center experience, systematic review and meta-analysis

Pancreatology ◽  
2017 ◽  
Vol 17 (3) ◽  
pp. S14-S15
Author(s):  
Giovanni Marchegiani ◽  
Stefano Andrianello ◽  
Alex Borin ◽  
Chiara Dal Borgo ◽  
Giampaolo Perri ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
High Volume ◽  
High Volume Center ◽  
Mural Nodules

scholarly journals Prognostic value of mural nodules and their size in IPMN of the pancreas: high-volume center experience, systematic review and meta-analysis

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S1012
Author(s):  
G. Marchegiani ◽  
S. Andrianello ◽  
A. Borin ◽  
C. Dal Borgo ◽  
G. Perri ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
High Volume ◽  
High Volume Center ◽  
Mural Nodules

scholarly journals Prognostic value of mural nodules and their size in IPMN of the pancreas: high-volume center experience, systematic review and meta-analysis

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S734-S735
Author(s):  
G. Marchegiani ◽  
S. Andrianello ◽  
A. Borin ◽  
C. Dal Borgo ◽  
G. Perri ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
High Volume ◽  
High Volume Center ◽  
Mural Nodules

Systematic review, meta-analysis, and a high-volume center experience supporting the new role of mural nodules proposed by the updated 2017 international guidelines on IPMN of the pancreas

Surgery ◽  
2018 ◽  
Vol 163 (6) ◽  
pp. 1272-1279 ◽  
Author(s):  
Giovanni Marchegiani ◽  
Stefano Andrianello ◽  
Alex Borin ◽  
Chiara Dal Borgo ◽  
Giampaolo Perri ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
High Volume ◽  
International Guidelines ◽  
High Volume Center ◽  
Mural Nodules

scholarly journals Prognostic value of Neutrophil‐to‐lymphocyte ratio in COVID‐19 patients: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Juan R. Ulloque‐Badaracco ◽  
W. Ivan Salas‐Tello ◽  
Ali Al‐kassab‐Córdova ◽  
Esteban A. Alarcón‐Braga ◽  
Vicente A. Benites‐Zapata ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals Tumor-Infiltrating Lymphocytes in the Tumor Microenvironment of Laryngeal Squamous Cell Carcinoma: Systematic Review and Meta-Analysis

Biomedicines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 486
Author(s):  
Juan P. Rodrigo ◽  
Mario Sánchez-Canteli ◽  
Fernando López ◽  
Gregory T. Wolf ◽  
Juan C. Hernández-Prera ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Tumor Microenvironment ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Value ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Meta Analysis ◽  
Tumor Infiltrating Lymphocytes ◽  
Infiltrating Lymphocytes

The presence of tumor-infiltrating lymphocytes (TIL) in the tumor microenvironment has been demonstrated to be of prognostic value in various cancers. In this systematic review and meta-analysis, we investigated the prognostic value of TIL in laryngeal squamous cell carcinoma (LSCC). We performed a systematic search in PubMed for publications that investigated the prognostic value of TIL in LSCC. A meta-analysis was performed including all studies assessing the association between TIL counts in hematoxylin-eosin (HE)-stained sections, for CD8+ and/or CD3+/CD4+ TIL and overall survival (OS) or disease-free survival (DFS). The pooled meta-analysis showed a favorable prognostic role for stromal TIL in HE sections for OS (HR 0.57, 95% CI 0.36–0.91, p = 0.02), and for DFS (HR 0.56, 95% CI 0.34–0.94, p = 0.03). High CD8+ TIL were associated with a prolonged OS (HR 0.62, 95% CI 0.4–0.97, p = 0.04) and DFS (HR 0.73, 95% CI 0.34–0.94, p = 0.002). High CD3+/CD4+ TIL demonstrated improved OS (HR 0.32, 95% CI 0.16–0.9, p = 0.03) and DFS (HR 0.23, 95% CI 0.10–0.53, p = 0.0005). This meta-analysis confirmed the favorable prognostic significance of TIL in LSCC. High stromal TIL evaluated in HE sections and intra-tumoral and stromal CD3+, CD4+ and/or CD8+ TIL might predict a better clinical outcome.

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