Primary mucinous retroperitoneal tumour of borderline malignant potential – a case report

Thymic neuroendocrine carcinomas (carcinoid) are rare tumors. They have malignant potential, the capacity for distant metastasis, and often present with associated endocrinopathies. This report describes a patient who was diagnosed with thymic carcinoid and Cushing syndrome at age 19 that, despite complete surgical excision of his tumor, developed local recurrence with distant metastases to his brain, lungs, and bone. We discuss the evolution of this patient's illness as well as the therapies used in his care. Due to the nature of these tumors to recur both locally and distant, the importance of aggressive surgical management is emphasized. We also discuss the role of adjuvant therapy, which in our case consisted of chemotherapy, radiotherapy, and several new therapies including an antiangiogenesis agent and a tyrosine kinase inhibitor.

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Mediastinal smooth muscle tumor of uncertain malignant potential: case report and literature review

Medicina Fluminensis ◽

10.21860/medflum2019_216315 ◽

2019 ◽

Vol 55 (1) ◽

pp. 89-94

Author(s):

Veljko Flego ◽

Darian Volarić ◽

Koviljka Matušan Ilijaš ◽

Ljiljana Bulat-Kardum

Keyword(s):

Smooth Muscle ◽

Case Report ◽

Literature Review ◽

Smooth Muscle Tumor ◽

Malignant Potential ◽

Uncertain Malignant Potential ◽

Potential Case ◽

Muscle Tumor

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Low grade prostatic stromal sarcoma arising in a stromal tumour of uncertain malignant potential: a case report

Pathology ◽

10.1016/s0031-3025(16)32876-8 ◽

2012 ◽

Vol 44 ◽

pp. S96

Author(s):

Jonathan Smiles ◽

Lavinia Hallam

Keyword(s):

Case Report ◽

Malignant Potential ◽

Stromal Tumour ◽

Low Grade ◽

Uncertain Malignant Potential ◽

Stromal Sarcoma

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Oncocytic adrenocortical neoplasm: a rare tumour of uncertain malignant potential: a case report

Pathology ◽

10.1097/01268031-200941001-00125 ◽

2009 ◽

Vol 41 ◽

pp. 58

Author(s):

Rakhi Bhuta ◽

Alfred Lam ◽

Queenie Lau

Keyword(s):

Case Report ◽

Malignant Potential ◽

Uncertain Malignant Potential ◽

Rare Tumour ◽

Adrenocortical Neoplasm

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Gingival Enlargement in Neurofibromatosis Type 1: A Case Report and Literature Review

The Journal of Contemporary Dental Practice ◽

10.5005/jcdp-11-2-57 ◽

2010 ◽

Vol 11 (2) ◽

pp. 57-63 ◽

Cited By ~ 6

Author(s):

Ashu Bhardwaj ◽

Ajay Mahajan

Keyword(s):

Case Report ◽

Literature Review ◽

Neurofibromatosis Type 1 ◽

Neurofibromatosis Type ◽

Skin Lesions ◽

Neurological Complications ◽

Malignant Potential ◽

Gingival Tissue ◽

Gingival Enlargement

Abstract Aim The purpose of this article is to describe a rare case of neurofibromatosis1 (NF1) of the gingiva and a review of the current literature. Background Neurofibromatosis1 (NF1) of the gingiva is an uncommon cause of gingival enlargement. The disease is clinically characterized by epidermal melanosis, nevi, and flabby skin or bone malformations; in addition, the lesions may undergo malignant transformation. Involvement of the gingiva with or without concurrent skin lesions has been reported only occasionally. Case Description A 40-year-old male patient with a history of NF1 came to us with a chief complaint of enlargement of the gums. Clinical examination revealed diffuse gingival enlargement with no signs of inflammation. The characteristic skin lesions associated with NF1 were also present. A gingival specimen was sent for biopsy. Results Based on the history, clinical, and histological findings, NF1 was established as the cause of the gingival enlargement. Summary NF1 may affect the gingival tissue; considering the neurological complications and malignant potential, NF1 must be diagnosed early and monitored regularly. Clinical Significance The clinician should be aware of clinical and histopathological findings of NF1 considering the fact that the condition has malignant potential. Citation Mahajan A, Dixit J, Bhardwaj A. Gingival Enlargement in Neurofibromatosis Type 1: A Case Report and Literature Review. J Contemp Dent Pract [Internet]. 2010 March; 11(2):057-063. Available from: http://www.thejcdp. com/journal/view/volume11-issue2-mahajan.

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