Efficacy and safety of 5-aminolevulinic acid photodynamic therapy for the treatment of ulcerative squamous cell carcinoma

2020 ◽  
Vol 30 ◽  
pp. 101710
Author(s):  
Liwen Dong ◽  
Xinying Li ◽  
Xiaoxiao Shen ◽  
Wanqi Zhang ◽  
Junbo Zhang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Aminolevulinic Acid ◽  
Efficacy And Safety

5-Aminolevulinic acid photodynamic therapy for early-stage lip squamous cell carcinoma

2021 ◽  
pp. 102321
Author(s):  
Peiru Wang ◽  
Guolong Zhang ◽  
Linglin Zhang ◽  
Zhongxia Zhou ◽  
Lei Shi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Aminolevulinic Acid ◽  
Early Stage

Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma

Head & Neck ◽  
2009 ◽  
Vol 32 (9) ◽  
pp. 1136-1142 ◽  
Author(s):  
Yeon-Hee Moon ◽  
Jong-Hwan Park ◽  
Soo-A Kim ◽  
Jee-Bum Lee ◽  
Sang-Gun Ahn ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Aminolevulinic Acid ◽  
Anticancer Effect

Multiple Large-Surface Photodynamic Therapy Sessions with Topical or Systemic Aminolevulinic Acid and Blue Light in UV-Exposed Hairless Mice

2004 ◽  
Vol 8 (2) ◽  
pp. 131-139 ◽  
Author(s):  
Younan Liu ◽  
Gilles Viau ◽  
Robert Bissonnette
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Cell Carcinoma ◽  
Blue Light ◽  
Uv Radiation ◽  
Squamous Cell ◽  
Aminolevulinic Acid ◽  
Hairless Mice ◽  
Free Survival ◽  
Actinic Keratoses

Background: The use of photodynamic therapy (PDT) with topical aminolevulinic acid (ALA) on large skin surfaces has recently been reported for patients with multiple actinic keratoses. Objective: The current study compared the ability of topical and systemic ALA–PDT as well as topical ALA–PDT with blue light to delay the appearance of UV-induced skin cancer using the hairless mouse as a model. Methods: Groups of hairless mice were exposed daily to UV radiation and weekly to ALA–PDT. Tumor-free survival was compared for mice exposed to UV and treated weekly with ALA–PDT and mice exposed only to UV radiation. Results: Weekly topical or systemic ALA–PDT was able to delay the induction of skin tumors. A significant difference in tumor-free survival was also observed for both actinic keratoses and invasive squamous cell carcinoma in mice treated weekly with topical ALA–PDT performed with blue light. This was observed even when weekly ALA–PDT was started after 8 weeks of UV exposure. Conclusion: Large-surface topical ALA–PDT with blue light can delay the appearance of UV-induced actinic keratoses and squamous cell carcinoma in hairless mice.

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