Copolymer-nanocapsules of zinc phenyl-thio-phthalocyanine and amphotericin-B in association with antimicrobial photodynamic therapy (A-PDT) applications against Candida albicans yeasts

2021 ◽  
Vol 34 ◽  
pp. 102273
Author(s):  
Rodrigo P. Evangelista ◽  
Camila F. Amantino ◽  
Rosemeire C.L.R. Pietro ◽  
Rodrigo Sorrechia ◽  
Rodolfo D. Piazza ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Amphotericin B ◽  
Antimicrobial Photodynamic Therapy

DNase increases the efficacy of antimicrobial photodynamic therapy on Candida albicans biofilms

2019 ◽  
Vol 27 ◽  
pp. 124-131 ◽  
Author(s):  
Beatriz H.D. Panariello ◽  
Marlise I. Klein ◽  
Fernanda Alves ◽  
Ana Cláudia Pavarina
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Candida Albicans Biofilms

scholarly journals Antimicrobial Photodynamic Therapy in Combination with Nystatin in the Treatment of Experimental Oral Candidiasis Induced by Candida albicans Resistant to Fluconazole

2019 ◽  
Vol 12 (3) ◽  
pp. 140 ◽  
Author(s):  
Karem Janeth Rimachi Hidalgo ◽  
Juliana Cabrini Carmello ◽  
Cláudia Carolina Jordão ◽  
Paula Aboud Barbugli ◽  
Carlos Alberto de Sousa Costa ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Combined Therapy ◽  
Oral Candidiasis ◽  
Confocal Scanning Laser Microscopy ◽  
Antimicrobial Photodynamic Therapy ◽  
Promising Alternative ◽  
Confocal Scanning ◽  
Confocal Scanning Laser

Background: It has been demonstrated that azole-resistant strains of Candida albicans have a greater resistance to antimicrobial photodynamic therapy (aPDT) when compared to their more susceptible counterparts. For this reason, the present study evaluated the efficacy of aPDT, together with nystatin (NYS), in the treatment of oral candidiasis in vivo. Methods: Mice were infected with fluconazole-resistant C. albicans (ATCC 96901). To perform the combined therapy, aPDT, mediated by Photodithazine (PDZ) and LED light, was used together with NYS. The efficacy of the treatments was evaluated by microbiological, macroscopic, histopathological and Confocal Scanning Laser Microscopy analyses of the lesions. The expression of p21 and p53, proteins associated with cell death, from the tongues of mice, was also performed. Results: The combined therapy reduced the fungal viability by around 2.6 log10 and decreased the oral lesions and the inflammatory reaction. Additionally, it stimulated the production of p53 and p21. Conclusions: The combined therapy is a promising alternative treatment for oral candidiasis induced by C. albicans resistant to fluconazole.

scholarly journals Application of benzo[a]phenoxazinium chlorides in antimicrobial photodynamic therapy of Candida albicans biofilms

2014 ◽  
Vol 141 ◽  
pp. 93-99 ◽  
Author(s):  
Marisa Lopes ◽  
Carlos Tiago Alves ◽  
B. Rama Raju ◽  
M. Sameiro T. Gonçalves ◽  
Paulo J.G. Coutinho ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Candida Albicans Biofilms

scholarly journals Action of antimicrobial photodynamic therapy on heterotypic biofilm: Candida albicans and Bacillus atrophaeus

2016 ◽  
Vol 31 (4) ◽  
pp. 605-610 ◽  
Author(s):  
Michelle Peneluppi Silva ◽  
Thais Alves dos Santos ◽  
Patrícia Pimentel de Barros ◽  
Felipe de Camargo Ribeiro ◽  
Juliana Campos Junqueira ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Bacillus Atrophaeus

scholarly journals Antimicrobial photodynamic therapy in rat experimental candidiasis: evaluation of pathogenicity factors of Candida albicans

2011 ◽  
Vol 111 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Joyce da Silva Martins ◽  
Juliana Campos Junqueira ◽  
Raquel Lourdes Faria ◽  
Naiara Fonseca Santiago ◽  
Rodnei Dennis Rossoni ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Pathogenicity Factors

Antimicrobial photodynamic therapy reduces adhesion capacity and biofilm formation of Candida albicans from induced oral candidiasis in mice

2019 ◽  
Vol 27 ◽  
pp. 402-407 ◽  
Author(s):  
Juliana Cabrini Carmello ◽  
Fernanda Alves ◽  
Fernanda G. Basso ◽  
Carlos Alberto de Souza Costa ◽  
Antônio Cláudio Tedesco ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Biofilm Formation ◽  
Oral Candidiasis ◽  
Antimicrobial Photodynamic Therapy

scholarly journals The effects of aloe emodin-mediated antimicrobial photodynamic therapy on drug-sensitive and resistant Candida albicans

2020 ◽  
Vol 19 (4) ◽  
pp. 485-494 ◽  
Author(s):  
Wenpeng Ma ◽  
Chengcheng Liu ◽  
Jiao Li ◽  
Ming Hao ◽  
Yanhong Ji ◽  
...  
Keyword(s):  
Cell Wall ◽  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Aloe Emodin

Aloe emodin-mediated antimicrobial photodynamic therapy effectively inactivated drug-sensitive and resistant C. albicans and caused damage to the cell wall, cytoplasm, and nucleus.

Antimicrobial photodynamic therapy reduces gene expression of Candida albicans in biofilms

2020 ◽  
Vol 31 ◽  
pp. 101825 ◽  
Author(s):  
Cláudia Carolina Jordão ◽  
Tábata Viana de Sousa ◽  
Marlise Inêz Klein ◽  
Luana Mendonça Dias ◽  
Ana Cláudia Pavarina ◽  
...  
Keyword(s):  
Gene Expression ◽  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Antimicrobial Photodynamic Therapy

Successive applications of Antimicrobial Photodynamic Therapy effects the susceptibility of Candida albicans grown in medium with or without fluconazole

2020 ◽  
Vol 32 ◽  
pp. 102018
Author(s):  
Luana Mendonça Dias ◽  
Marlise Inêz Klein ◽  
Cláudia Carolina Jordão ◽  
Juliana Cabrini Carmello ◽  
Amanda Bellini ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Photodynamic Therapy ◽  
Antimicrobial Photodynamic Therapy
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