scholarly journals Development of a robust blood smear preparation procedure for external quality assessment

2021 ◽  
pp. e00253
Author(s):  
Quang Huy Vu ◽  
Hy Triet Van ◽  
Van Thanh Tran ◽  
Nhat Nguyen Tran ◽  
Thi Diem Phuc Huynh ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Blood Smear ◽  
External Quality Assessment ◽  
Preparation Procedure ◽  
External Quality ◽  
Smear Preparation

Guidelines for blood smear preparation and staining procedure for setting up an external quality assessment scheme for blood smear interpretation. Part I: control material

2004 ◽  
Vol 42 (8) ◽  
Author(s):  
Juan-Lluis Vives Corrons ◽  
Stephanie Albarède ◽  
George Flandrin ◽  
Silke Heller ◽  
Katalin Horvath ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Blood Smear ◽  
External Quality Assessment ◽  
Clinical Chemistry ◽  
Staining Procedure ◽  
Guidance Document ◽  
External Quality ◽  
External Quality Assessment Scheme ◽  
Smear Preparation ◽  
Set Up

AbstractBlood smear analysis is a well known technique in medical laboratories. Clinical relevance of this analysis and its interpretation are very important. Consequently, monitoring of laboratory performance by an external quality assessment scheme is strongly recommended. Most starting external quality organizers set up a scheme for clinical chemistry. Due to a lack of guidance documents, many organizers are reluctant to offer a hematology scheme. This article aims to be a very practical guidance document for external quality assessment organizers for the set up of blood smear schemes.

Guidelines for setting up an External Quality Assessment Scheme for blood smear interpretation. Part II: survey preparation, statistical evaluation and reporting

2006 ◽  
Vol 44 (8) ◽  
Keyword(s):  
Quality Assessment ◽  
Blood Smear ◽  
Statistical Evaluation ◽  
External Quality Assessment ◽  
Virtual Microscopy ◽  
Guidance Document ◽  
External Quality ◽  
External Quality Assessment Scheme ◽  
Medical Laboratories ◽  
Blood Smears

AbstractBlood smear analysis is a well-known technique in medical laboratories. The clinical relevance of this analysis and its interpretation are very important. Consequently, monitoring of laboratory performance by an external quality assessment scheme is strongly recommended. This article represents a very practical guidance document for External Quality Assessment Scheme (EQAS) organizers for setting up blood smear schemes. In the first part of the guidelines, the Hematology Working Group of the European External Committee for External Quality Assurance Programmes in Laboratory Medicine (EQALM) published practical information for the preparation of blood smears for use in an EQAS. Part II focuses on aspects such as survey preparation, statistical evaluation and reporting, and describes particular details for organizing blood morphology EQA surveys by means of virtual microscopy.Clin Chem Lab Med 2006;44:1039–43.

scholarly journals The versatility of external quality assessment for the surveillance of laboratory and in vitro diagnostic performance: SARS-CoV-2 viral genome detection in Austria

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Christoph Buchta ◽  
Jeremy V. Camp ◽  
Jovana Jovanovic ◽  
Peter Chiba ◽  
Elisabeth Puchhammer-Stöckl ◽  
...  
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
False Negative ◽  
Positive Sample ◽  
Performance Criteria ◽  
External Quality ◽  
Assay Sensitivity ◽  
Dilution Series ◽  
Test Systems

Abstract Objectives External quality assessment (EQA) schemes provide information on individual and general analytical performance of participating laboratories and test systems. The aim of this study was to investigate the use and performance of SARS-CoV-2 virus genome detection systems in Austrian laboratories and their preparedness to face challenges associated with the pandemic. Methods Seven samples were selected to evaluate performance and estimate variability of reported results. Notably, a dilution series was included in the panel as a measure of reproducibility and sensitivity. Several performance criteria were evaluated for individual participants as well as in the cohort of all participants. Results A total of 109 laboratories participated and used 134 platforms, including 67 different combinations of extraction and PCR platforms and corresponding reagents. There were no false positives and 10 (1.2%) false negative results, including nine in the weakly positive sample (C t ∼35.9, ∼640 copies/mL). Twenty (22%) laboratories reported results of mutation detection. Twenty-five (19%) test systems included amplification of human RNA as evidence of proper sampling. The overall linearity of C t values from individual test systems for the dilution series was good, but inter-assay variability was high. Both operator-related and systematic failures appear to have caused incorrect results. Conclusions Beyond providing certification for participating laboratories, EQA provides the opportunity for participants to evaluate their performance against others so that they may improve operating procedures and test systems. Well-selected EQA samples offer additional inferences to be made about assay sensitivity and reproducibility, which have practical applications.

Commutability of possible external quality assessment materials for progesterone measurement

2021 ◽  
Vol 87 ◽  
pp. 39-45
Author(s):  
Xilian Yi ◽  
Yufei Wang ◽  
Tianjiao Zhang ◽  
Jie Zeng ◽  
Haijian Zhao ◽  
...  
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
External Quality

Appropriateness of cholesterol and triglycerides reporting checked by External Quality Assessment programs

2003 ◽  
Vol 333 (2) ◽  
pp. 221-230 ◽  
Author(s):  
Sandra Secchiero ◽  
Laura Sciacovelli ◽  
Lorena Zardo ◽  
Mario Plebani
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
External Quality
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