On the relation of gyrification and cortical thickness alterations to the suicidal risk and mental pain in chronic schizophrenia outpatients

Author(s):  
Bartosz Bohaterewicz ◽  
Anna Maria Sobczak ◽  
Alicja Krześniak ◽  
Dagmara Mętel ◽  
Przemysław Adamczyk
2020 ◽  
pp. 003022282098123
Author(s):  
Yossi Levi-Belz ◽  
Yari Gvion ◽  
Alan Apter

The study of survivors of a serious suicide attempt (SSA)––an attempt that would have been fatal had it not been for the provision of rapid and effective emergency treatment––can help researchers understand the suicidal mind. Serious suicide attempters are epidemiologically very similar to those who died by suicide, and thus can serve as valid proxies for studying suicides. In this paper, our objective was to briefly review the main risk factors that may facilitate more dangerous suicide behavior with high levels of intent. Our review highlights several dimensions of risk factors for SSAs, including psychopathology, mental pain, communication difficulties, decision-making impulsivity, and aggression. Several studies have indicated that the interaction between some of these dimensions, especially between mental pain and interpersonal difficulties, may serve as major catalysts for SSAs. Suicidal risk assessment should incorporate a designated evaluation of these risk factors as part of suicide prevention models.


Author(s):  
Fabrice Jollant ◽  
Jamie Near ◽  
Gustavo Turecki ◽  
Stéphane Richard-Devantoy

2015 ◽  
Vol 206 (6) ◽  
pp. 479-483 ◽  
Author(s):  
Igor Nenadic ◽  
Rachel A. Yotter ◽  
Heinrich Sauer ◽  
Christian Gaser

BackgroundAlterations of cortical thickness have been shown in imaging studies of schizophrenia but it is unclear to what extent they are related to disease phenotype (including symptom profile) or other aspects such as genetic liability, disease onset and disease progression.AimsTo test the hypothesis that cortical thinning would vary across different subgroups of patients with chronic schizophrenia, delineated according to their symptom profiles.MethodWe compared high-resolution magnetic resonance imaging data of 87 patients with DSM-IV schizophrenia with 108 controls to detect changes in cortical thickness across the entire brain (P<0.05, false discovery rate-adjusted). The patient group was divided into three subgroups, consisting of patients with predominantly negative, disorganised or paranoid symptoms.ResultsThe negative symptoms subgroup showed the most extensive cortical thinning, whereas thinning in the other subgroups was focused in prefrontal and temporal cortical subregions.ConclusionsOur findings support growing evidence of potential subtypes of schizophrenia that have different brain structural deficit profiles.


2015 ◽  
Vol 71 (4) ◽  
pp. 225-233 ◽  
Author(s):  
Li Kong ◽  
Christina J. Herold ◽  
Marc M. Lässer ◽  
Lena A. Schmid ◽  
Dusan Hirjak ◽  
...  

2012 ◽  
Vol 22 (1) ◽  
pp. 73-80
Author(s):  
June Sic Kim ◽  
Chun Kee Chung ◽  
Hang Joon Jo ◽  
Jong Min Lee ◽  
Jun Soo Kown

Crisis ◽  
2012 ◽  
Vol 33 (2) ◽  
pp. 80-86 ◽  
Author(s):  
Sami Hamdan ◽  
Nadine Melhem ◽  
Israel Orbach ◽  
Ilana Farbstein ◽  
Mohammad El-Haib ◽  
...  

Background: Relatively little is known about the role of protective factors in an Arab population in the presence of suicidal risk factors. Aims: To examine the role of protective factors in a subsample of in large Arab Kindred participants in the presence of suicidal risk factors. Methods: We assessed protective and risk factors in a sample of 64 participants (16 suicidal and 48 nonsuicidal) between 15 and 55 years of age, using a comprehensive structured psychiatric interview, the Composite International Diagnostic Interview (CIDI), self-reported depression, anxiety, hopelessness, impulsivity, hostility, and suicidal behavior in first-degree and second-relatives. We also used the Religiosity Questionnaire and suicide attitude (SUIATT) and multidimensional perceived support scale. Results: Suicidal as opposed to nonsuicidal participants were more likely to have a lifetime history of major depressive disorder (MDD) (68.8% vs. 22.9% χ2 = 11.17, p = .001), an anxiety disorder (87.5% vs. 22.9, χ2 = 21.02, p < .001), or posttraumatic stress disorder (PTSD) (25% vs. 0.0%, Fisher’s, p = .003). Individuals who are otherwise at high risk for suicidality have a much lower risk when they experience higher perceived social support (3.31 ± 1.36 vs. 4.96 ± 1.40, t = 4.10, df = 62, p < .001), and they have the view that suicide is somehow unacceptable (1.83 ± .10 vs. 1.89 ± .07, t = 2.76, df = 60, p = .008). Conclusions: Taken together with other studies, these data suggest that the augmentation of protective factors could play a very important role in the prevention of incidental and recurrent suicidal behavior in Arab populations, where suicidal behavior in increasing rapidly.


2015 ◽  
Author(s):  
Tina Yu ◽  
Zunaira Jilani ◽  
Edward C. Chang ◽  
Erin E. Fowler ◽  
Jiachen Lin ◽  
...  

2019 ◽  
Vol 43 (1) ◽  
pp. 3-16 ◽  
Author(s):  
R. Elizabeth Capps ◽  
Kurt D. Michael ◽  
J. P. Jameson
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document