AimTo assess the efficacy of Metacognitive Training (MCT) in symptoms and metacognitive variables in people with a recent onset of psychosis.MethodA multicenter, randomized and controlled clinical trial was performed. One hundred and twenty-six patients were randomized to MCT or a psycho-educational intervention. Patients with a recent onset of psychosis were recruited from 9 centers of Spain. The treatment consisted in 8 weekly sessions in both groups. Patients were assessed at baseline, post-treatment, and 6 months of follow-up. Symptoms were assessed by the PANSS. Metacognition was assessed by a battery of questionnaires of cognitive biases and social cognition: BCIS, IPSAQ, TCI, Hinting task and Emotional Recognition Test.ResultsPANSS positive symptoms significant declined between baseline and post-treatment in psycho-educational (P = 0.04) and MCT group (P = 0.01), while general PANSS and total PANSS were significant between baseline and post-treatment in the MCT group only (P = 0.008; P = 0.005). Across time, the MCT group was superior to psycho-educational on the BCIS total and self-certainty subscale (P = 0.042). Regarding irrational beliefs, the intolerance to frustration subscale declined more strongly in the MCT in relation to psycho-educational group (P = 0.016). ToM, Personalizing Bias and JTC improved more strongly in the MCT group compared to psycho-educational group (P < 0.001–0.032). Most results remained significant at the follow-up.ConclusionsMCT could be an effective psychological intervention for people with a recent onset of psychosis in order to improve symptoms, insight, tolerance to frustration and personalizing bias.Disclosure of interestThe authors have not supplied their declaration of competing interest.
F212. IMPROVEMENT IN COGNITIVE BIASES AFTER GROUP PSYCHOEDUCATION AND METACOGNITIVE TRAINING IN RECENT ONSET PSYCHOSIS