scholarly journals Longitudinal evidence of the impact of normal thyroid stimulating hormone variations on cognitive functioning in very old age

2005 ◽  
Vol 30 (7) ◽  
pp. 625-637 ◽  
Author(s):  
Åke Wahlin ◽  
David Bunce ◽  
Tarja-Brita Robins Wahlin
1998 ◽  
Vol 53B (4) ◽  
pp. P234-P239 ◽  
Author(s):  
A. Wahlin ◽  
T.-B. R. Wahlin ◽  
B. J. Small ◽  
L. Backman

2001 ◽  
Vol 56 (3) ◽  
pp. 247-265 ◽  
Author(s):  
Tarja-Brita Robins Wahlin ◽  
Åke Wahlin ◽  
Bengt Winblad ◽  
Lars Bäckman

2020 ◽  
Vol 8 (5) ◽  
Author(s):  
Yulia Griber ◽  
Yulia Ustimenko

The goal of the paper is to present the theoretical foundations of a unique training program aimed at providing students with a complex of knowledge, skills and abilities needed to understand the specifics of color communication in old and very old age. The objectives of the paper include an analytical review of the sources that have defined the program content, the structure of the educational module, and its methodological basis. The selection of research sources was carried out through the RSCI, Google Scholar, Scopus, and Web of Science systems. In the process of work the methods of theoretical and comparative analysis, systematization and generalization of materials were used. The authors provide a detailed analysis of the sources, which represent the dynamics of age-related physiological changes in color vision and examine their impact on color communication of elderly people. Each of the theoretical models included into the review makes a special contribution to the development of the problem. The experiments with colored glasses of K. Ishihara et al. provide an opportunity to feel the impact of age-related decline in visual ability on everyday life and habits of an aging person. The research of D.T. Lindsay and A.M. Brown helps to understand how aging of the eye influences perception of individual shades. The method of M.F. Hassan's research group simulates how elderly people see different color combinations and complex images. An optical google of T. Suzuki et al. enables young people to experience senile miosis in any environment in real time under different illuminance conditions. J.L. Hardy's et al. experiment explains why elderly people often do not realize that their color perception is changing. In the complex, all the studies presented in the review help students to better understand the specifics of color communication in old and very old age, and thus to form a sustainable complex of knowledge, skills and abilities necessary for improving the quality of color design projects, creating by young professionals for elderly people


2007 ◽  
Vol 2 (1) ◽  
pp. 9-31 ◽  
Author(s):  
Stefano Cavalli ◽  
Jean-François Bickel ◽  
Christian J. Lalive d´Epinay

This paper focuses on relational exclusion (i.e. isolation and non-participation in social activities) in very old age. Based on a five-year study of an octogenarian cohort, the authors investigate the impact of three critical life events (deterioration of health, death of a close relative, entry into a nursing home) on relational life and social involvement. With advancing age, older people withdraw from some social activities, but their relationships with their family and friends remain stable. Life events have a stimulative effect on the support network (especially of family), and only the deterioration of health curbs social activity. This would seem to confirm the existence of a process of disengagement stemming more from the older people’s functional or sensory disabilities than from an individual choice.


Author(s):  
Marcella Reissmann ◽  
Luise Geithner ◽  
Anna Storms ◽  
Christiane Woopen

Abstract Background People in very old age (VOA) are expected to be confronted with particularly negative stereotypes. These influence societally shared behavior towards and judgements about them. Such external evaluations of individuals’ lives are considered a crucial part of their quality of life (QoL). Objective The present study elaborated a) the societal appreciation perceived by people in VOA and b) the stereotypes about people in VOA held by stakeholders from key societal areas. The aim was to discuss possible connections between these external standards and individual life results. Material and methods A parallel mixed methods design was employed. Cross-sectional data from a representative survey of people aged 80 years and older (n = 1863) were analyzed by means of χ2-tests and Kruskal-Wallis tests to examine differences in perceived societal appreciation (PSA) by characteristics of the person, their biography, and current lifestyle. Linear regression models were used to investigate the impact of these characteristics on PSA. Regarding stereotypes about people in VOA, semi-structured interviews with stakeholders from key societal areas (n = 22) were analyzed using qualitative content analysis. The quantitative and qualitative findings were juxtaposed for comparison. Results PSA was predicted by health-related variables and productive activities. Several societal stakeholders highlighted that age-related losses pose challenges on very old individuals, their families, and society, whereas remaining potentials in VOA can and should be used for the benefit of others; however, stakeholders‘ perceptions differed by the extent of their professional contact with (very) old people. Different pathways were proposed through which the observed stereotypes and determinants of PSA might be connected (e.g., stereotype internalization). Conclusion Our study illustrates the relevance of external standards for individual QoL and highlights the need for a normative perspective in the discussion about QoL and its enhancement.


1990 ◽  
Vol 2 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Anthony Duncan ◽  
Gabor Ungvari ◽  
Robert Russell ◽  
Annalise Seifert

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tuo Deng ◽  
Wenwen Zhang ◽  
Yanling Zhang ◽  
Mengqi Zhang ◽  
Zhikun Huan ◽  
...  

Abstract Background As the incidence of secretory osteoporosis has increased, bone loss, osteoporosis and their relationships with thyroid-stimulating hormone (TSH) have received increased attention. In this study, the role of TSH in bone metabolism and its possible underlying mechanisms were investigated. Methods We analyzed the serum levels of free triiodothyronine (FT3), free thyroxine (FT4), and TSH and the bone mineral density (BMD) levels of 114 men with normal thyroid function. In addition, osteoblasts from rat calvarial samples were treated with different doses of TSH for different lengths of time. The related gene and protein expression levels were investigated. Results A comparison of the BMD between the high-level and low-level serum TSH groups showed that the TSH serum concentration was positively correlated with BMD. TSH at concentrations of 10 mU/mL and 100 mU/mL significantly increased the mRNA levels of ALP, COI1 and Runx2 compared with those of the control (P < 0.05, P < 0.01). Bone morphogenetic protein (BMP)2 activity was enhanced with both increased TSH concentration and increased time. The protein levels of Runx2 and osterix were increased in a dose-dependent manner. Conclusions The circulating concentrations of TSH and BMD were positively correlated with normal thyroid function in males. TSH promoted osteoblast proliferation and differentiation in rat primary osteoblasts.


2003 ◽  
Vol 18 (2) ◽  
pp. 193-202 ◽  
Author(s):  
Brent J. Small ◽  
Laura Fratiglioni ◽  
Eva von Strauss ◽  
Lars Bäckman

2006 ◽  
Vol 7 ◽  
pp. S9-S10
Author(s):  
Donald Bliwise ◽  
Ian Colrain ◽  
Gary Swan ◽  
Laura-Beth Straight ◽  
Farzaneh Ansari ◽  
...  

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