The dosimetric impact of axillary nodes contouring variability in breast cancer radiotherapy: an AIRO multi-institutional study

2022 ◽  
Author(s):  
Maria Cristina Leonardi ◽  
Matteo Pepa ◽  
Rosa Luraschi ◽  
Sabrina Vigorito ◽  
Samantha Dicuonzo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Radiotherapy ◽  
Axillary Nodes ◽  
Breast Cancer Radiotherapy

PO-1480: Position in breast cancer radiotherapy: dosimetry and toxicity

2020 ◽  
Vol 152 ◽  
pp. S795-S796
Author(s):  
D. Hernandez ◽  
M.S. Talaya ◽  
C. Anson ◽  
P. Castro ◽  
M. Roch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
Radiotherapy Dosimetry

PH-0163: Harmonization of breast cancer radiotherapy treatment planning in the Netherlands

2020 ◽  
Vol 152 ◽  
pp. S77-S78
Author(s):  
M. Verhoeven ◽  
M. Sangen van der ◽  
C. Hurkmans ◽  
L. Boersma ◽  
K. Verhoeven ◽  
...  
Keyword(s):  
Breast Cancer ◽  
The Netherlands ◽  
Treatment Planning ◽  
Radiotherapy Treatment Planning ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
Radiotherapy Treatment

scholarly journals Estimating the Risks of Breast Cancer Radiotherapy: Evidence From Modern Radiation Doses to the Lungs and Heart and From Previous Randomized Trials

2017 ◽  
Vol 35 (15) ◽  
pp. 1641-1649 ◽  
Author(s):  
Carolyn Taylor ◽  
Candace Correa ◽  
Frances K. Duane ◽  
Marianne C. Aznar ◽  
Stewart J. Anderson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lung Cancer ◽  
Cardiac Mortality ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
The Absolute ◽  
Whole Heart ◽  
Meta Analyses ◽  
Modern Radiotherapy

Purpose Radiotherapy reduces the absolute risk of breast cancer mortality by a few percentage points in suitable women but can cause a second cancer or heart disease decades later. We estimated the absolute long-term risks of modern breast cancer radiotherapy. Methods First, a systematic literature review was performed of lung and heart doses in breast cancer regimens published during 2010 to 2015. Second, individual patient data meta-analyses of 40,781 women randomly assigned to breast cancer radiotherapy versus no radiotherapy in 75 trials yielded rate ratios (RRs) for second primary cancers and cause-specific mortality and excess RRs (ERRs) per Gy for incident lung cancer and cardiac mortality. Smoking status was unavailable. Third, the lung or heart ERRs per Gy in the trials and the 2010 to 2015 doses were combined and applied to current smoker and nonsmoker lung cancer and cardiac mortality rates in population-based data. Results Average doses from 647 regimens published during 2010 to 2015 were 5.7 Gy for whole lung and 4.4 Gy for whole heart. The median year of irradiation was 2010 (interquartile range [IQR], 2008 to 2011). Meta-analyses yielded lung cancer incidence ≥ 10 years after radiotherapy RR of 2.10 (95% CI, 1.48 to 2.98; P < .001) on the basis of 134 cancers, indicating 0.11 (95% CI, 0.05 to 0.20) ERR per Gy whole-lung dose. For cardiac mortality, RR was 1.30 (95% CI, 1.15 to 1.46; P < .001) on the basis of 1,253 cardiac deaths. Detailed analyses indicated 0.04 (95% CI, 0.02 to 0.06) ERR per Gy whole-heart dose. Estimated absolute risks from modern radiotherapy were as follows: lung cancer, approximately 4% for long-term continuing smokers and 0.3% for nonsmokers; and cardiac mortality, approximately 1% for smokers and 0.3% for nonsmokers. Conclusion For long-term smokers, the absolute risks of modern radiotherapy may outweigh the benefits, yet for most nonsmokers (and ex-smokers), the benefits of radiotherapy far outweigh the risks. Hence, smoking can determine the net effect of radiotherapy on mortality, but smoking cessation substantially reduces radiotherapy risk.

Cutaneous angiosarcoma: a rare complication post-male breast cancer radiotherapy

2017 ◽  
Vol 89 (1-2) ◽  
pp. 125-127
Author(s):  
Aaron Lim ◽  
Corina Preda ◽  
Jason Stone ◽  
Andreas L. Lambrianides
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Rare Complication ◽  
Male Breast ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy

scholarly journals Correlation between anthropometric parameters and acute skin toxicity in breast cancer radiotherapy patients: a pilot assessment study

2015 ◽  
Vol 88 (1055) ◽  
pp. 20150414 ◽  
Author(s):  
Benoîte Méry ◽  
Alexis Vallard ◽  
Jane-Chloé Trone ◽  
Cécile Pacaut ◽  
Jean-Baptiste Guy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Skin Toxicity ◽  
Anthropometric Parameters ◽  
Cancer Radiotherapy ◽  
Assessment Study ◽  
Breast Cancer Radiotherapy ◽  
Acute Skin Toxicity

scholarly journals Risk Evaluation of Secondary Cancer Induced by Breast Cancer Radiotherapy Treatment

2017 ◽  
Vol 08 (06) ◽  
Author(s):  
Ibrahim Duhaini ◽  
Fatima Hijazi ◽  
Eva Sabbah ◽  
Saad Ayoubi ◽  
Sadek Nehmeh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Evaluation ◽  
Secondary Cancer ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
Radiotherapy Treatment
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