Cloud computing has been proven to have numerous benefits for organizations, especially in supply chain management. More and more organizations have adopted cloud-based solutions to be their primary sourcing applications. Nevertheless, this technology is not without challenges, and in order to deploy and implement cloud-based solutions successfully with minimal risks organizations need to have practical guidance on this emerging technology. Despite the rapid growth of cloud computing in supply chain areas, the existing literature is still conceptual, inadequate, and mainly focused on the pre-adoption stage of this technology. This research examines the post-adoption stage of cloud-based supply chain solutions from the decision science perspective and intends to provide organizations with practical guidance on how to ensure the efficiency of a cloud-based supply chain system and control risks associated with cloud-based solutions.