scholarly journals Effects of fampridine on walking parameters, upper limb function, fatigue and quality of life in multiple sclerosis

2014 ◽  
Vol 57 ◽  
pp. e304
Author(s):  
A. Benoît ◽  
A. Blanchard ◽  
V. Tiffreau ◽  
A. Thévenon ◽  
P. Vermersch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Upper Limb ◽  
Limb Function ◽  
Upper Limb Function

scholarly journals Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response

2018 ◽  
Vol 76 (10) ◽  
pp. 654-662 ◽  
Author(s):  
Maicon Gabriel Gonçalves ◽  
Mariana Floriano Luiza Piva ◽  
Carlos Leonardo Sacomani Marques ◽  
Rafael Dalle Molle da Costa ◽  
Rodrigo Bazan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Virtual Reality ◽  
Upper Limb ◽  
Internal Capsule ◽  
Functional Independence ◽  
Reality Therapy ◽  
Limb Function ◽  
Virtual Reality Therapy ◽  
Upper Limb Function

ABSTRACT Background: Virtual reality therapy (VRT) is an interactive intervention that induces neuroplasticity. The aim was to evaluate the effects of VRT associated with conventional rehabilitation for an upper limb after stroke, and the neuroimaging predictors of a better response to VRT. Methods: Patients with stroke were selected, and clinical neurological, upper limb function, and quality of life were evaluated. Statistical analysis was performed using a linear model comparing pre- and post-VRT. Lesions were segmented in the post-stroke computed tomography. A voxel-based lesion-symptom mapping approach was used to investigate the relationship between the lesion and upper limb function. Results: Eighteen patients were studied (55.5 ± 13.9 years of age). Quality of life, functional independence, and dexterity of the upper limb showed improvement after VRT (p < 0.001). Neuroimaging analysis showed negative correlations between the internal capsule lesion and functional recovery. Conclusion: VRT showed benefits for patients with stroke, but when there was an internal capsule lesion, a worse response was observed.

Assessing upper limb function in multiple sclerosis

2014 ◽  
Vol 20 (7) ◽  
pp. 775-784 ◽  
Author(s):  
Ilse Lamers ◽  
Peter Feys
Keyword(s):  
Multiple Sclerosis ◽  
Outcome Measures ◽  
Upper Limb ◽  
International Classification Of Functioning ◽  
Limb Function ◽  
Upper Limb Function ◽  
High Prevalence ◽  
Upper Limb Dysfunction

The need to fully assess upper limb function in multiple sclerosis (MS) has become increasingly clear with recent studies revealing a high prevalence of upper limb dysfunction in persons with MS leading to increased dependency and reduced quality of life. It is important that clinicians and researchers use tailored outcome measures to systematically describe upper limb (dys)function and evaluate potential deterioration or improvement on treatment. This topical review provides a comprehensive summary of currently used upper limb outcome measures in MS, classified according to the levels of the International Classification of Functioning (ICF). The clinical utility, strengths, weaknesses and psychometric properties of common upper limb outcome measures are discussed. Based on this information, recommendations for selecting appropriate upper limb outcome measures are given. The current shortcomings in assessment which need to be addressed are identified.

scholarly journals QUALITY OF LIFE AND UPPER LIMB FUNCTION OF CHILDREN WITH NEONATAL BRACHIAL PLEXUS PALSY

2020 ◽  
Vol 38 ◽  
Author(s):  
Daiane Lazzeri de Medeiros ◽  
Natália Borges Agostinho ◽  
Luis Mochizuki ◽  
Anamaria Siriani de Oliveira
Keyword(s):  
Quality Of Life ◽  
Brachial Plexus ◽  
Upper Limb ◽  
Outcome Data ◽  
Emotional Impact ◽  
Brachial Plexus Palsy ◽  
Limb Function ◽  
Upper Limb Function ◽  
Neonatal Brachial Plexus Palsy

ABSTRACT Objective: To compare the upper limb function and quality of life between children with neonatal brachial plexus palsy and controls with unaffected brachial plexus (typical children). Methods: Twenty-four children with neonatal brachial plexus palsy and 24 typical ones were evaluated, both groups with 10±3 years of age. The upper limb function was assessed by the Modified Mallet Scale and the Active Movement Scale, whereas quality of life was analyzed by the Pediatric Outcome Data Collection Instrument and the Child Health Questionnaire. Mann-Whitney U tests investigated the differences between groups in such scales. Results: Children with neonatal brachial plexus palsy presented lower limb function compared to typical children in both scales. These children also presented lower scores for most of the Pediatric Outcome Data Collection Instrument domains, except for comfort/pain. In addition, they had lower scores in the following domains of the Child Health Questionnaire: physical functioning, pain, behavior, mental health, overall health perception, emotional impact on parents, and psychosocial summarized score. Conclusions: Neonatal brachial plexus palsy has a negative influence on upper limb function and quality of life, mainly considering overall health, basic mobility, physical and psychosocial functions, happiness, pain, behavior, mental health, upper limb function, and emotional impact on their parents.

scholarly journals HoMEcare aRm rehabiLItatioN (MERLIN): preliminary evidence of long term effects of telerehabilitation using an unactuated training device on upper limb function after stroke

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Samantha G. Rozevink ◽  
Corry K. van der Sluis ◽  
Juha M. Hijmans
Keyword(s):  
Quality Of Life ◽  
Upper Limb ◽  
Long Term Effects ◽  
Limb Function ◽  
Upper Limb Function ◽  
Arm Rehabilitation ◽  
Better Than

Abstract Background While short term effects on upper limb function of stroke patients after training with robotic devices have been studied extensively, long term effects are often not addressed. HoMEcare aRm rehabiLItatioN (MERLIN) is a combination of an unactuated training device using serious games and a telerehabilitation platform in the patient’s home situation. Short term effects showed that upper limb function improved after training with MERLIN. The aim was to determine long term effects on upper limb function and quality of life. Methods Six months after cessation of the 6 week MERLIN training program, the upper limb function and quality of life of 11 chronic stroke patients were assessed. Upper limb function was measured using the Wolf Motor Function Test (WMFT), Action Research Arm Test (ARAT) and Fugl-Meyer Assessment-Upper Extremity (FMA-UE). EuroQoL-5D (EQ-5D) was used to measure quality of life. Results The WMFT, ARAT and EQ-5D did not show significant differences 6 months after the training period compared to directly after training. At 6 months follow-up, FMA-UE results were significantly better than at baseline. Time plots showed a decreasing trend in all tests. Conclusion Training effects were still present at 6 months follow-up, since arm function seemed similar to directly after training and FMA-UE results were better than at baseline. However, because of the decreasing trend shown in all tests, it is questionable if improvements will be maintained longer than 6 months. Due to the sample size and study design, results should be interpreted with caution. Trial registration This study is registered at the Netherlands Trial Register (NL7535). Registered 18-02-2019, https://www.trialregister.nl/trial/7535

The Combined Effect of Dynamic Splinting and Neuromuscular Electrical Stimulation in Reducing Wrist and Elbow Contractures in Six Children with Cerebral Palsy

2010 ◽  
Vol 34 (1) ◽  
pp. 10-19 ◽  
Author(s):  
Neil Postans ◽  
Philip Wright ◽  
Will Bromwich ◽  
Ingrid Wilkinson ◽  
Sybil E. Farmer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cerebral Palsy ◽  
Electrical Stimulation ◽  
Range Of Motion ◽  
Upper Limb ◽  
Neuromuscular Electrical Stimulation ◽  
Limb Function ◽  
Upper Limb Function ◽  
Dynamic Splinting

The aim of this pilot study was to investigate the feasibility of applying the combination of Dynamic splinting (DS) and Neuromuscular electrical stimulation (NMES) in order to improve wrist and elbow function, and range of motion, in children with upper limb contractures due to Cerebral palsy (CP). Six children aged seven to 16, with contractures at the wrist or elbow, were recruited. Following a 12-week baseline period all participants underwent a 12-week treatment period where DS was used for one hour per day and combined with NMES for the second half of the 1-h treatment. A 12-week follow-up period then ensued. Upper limb function was assessed with the Melbourne assessment, physical disability with the Paediatric Evaluation of Disability Index and the Activity Scale for Kids, and quality of life with the Pediatric Quality of Life Scale. Passive and active range of motion at the wrist and elbow were measured using manual and electrical goniometers. The technique of using combined NMES and DS was demonstrated to be feasible and compliance with the intervention was good. There was an increase in passive elbow extension in two participants treated for elbow contractures, although no accompanying change in upper limb function was demonstrated. Wrist range of movement improved in one participant treated for wrist contracture.

scholarly journals Upper extremity function and quality of life in patients with breast cancer related lymphedema

2016 ◽  
Vol 73 (9) ◽  
pp. 825-830 ◽  
Author(s):  
Dragana Bojinovic-Rodic ◽  
Svetlana Popovic-Petrovic ◽  
Sanja Tomic ◽  
Stanislava Markez ◽  
Dobrinka Zivanic
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Mental Health ◽  
Upper Extremity ◽  
Upper Limb ◽  
Limb Function ◽  
Upper Limb Function ◽  
Upper Extremity Function ◽  
Breast Cancer Related Lymphedema

Background/Aim. Upper limb lymphedema is one of the most frequent chronic complications after breast cancer treatment with a significant impact on the upper extremity function and quality of life (QoL). The aim of this study was to estimate health-related quality of life (HRQoL) in patients with breast-cancer-related lymphedema and its correlation with upper limb function and the size of edema. Methods. The cross-sectional study included 54 breast-cancer-related lymphedema patients. The quality of life was evaluated by the Short Form 36-Item Health Survey (SF-36). Upper limb function was assessed by the Quick Disability of the Arm, Shoulder and Hand questionnaire (Quick DASH). The size of lymphedema was determined by the arm circumference. Results. The higher HRQoL score was assessed for mental health (47.0 ? 12.2) than for physical one (42.2 ? 7.5). The highest values of SF-36 were found in the domains of Mental Health (67.7 ? 22.9) and Social Function (70.1 ? 23.1). The lowest scores were registered in the domains of Role Physical (46.9 ? 39.1) and General Health (49.3 ? 20.1). Upper extremity function statistically significantly correlated with the domains Role Physical, Bodily Pain and Physical Composite Summary and also, with the domain Role Emotional (p < 0.01). There was no statistically significant correlation between size of lymphedema and tested domains of quality of life (p > 0.05). Conclusions. Physical disability in patients with breast cancer-related lymphedema influences quality of life more than mental health. Upper limb function has a significant impact on quality of life, not only on the physical, but also on the mental component. The presence of breast-cancer-related lymphedema certainly affects upper limb function and quality of life, but in this study no significant correlation between the size of edema and quality of life was found.

scholarly journals HoMEcare aRm rehabiLItatioN (MERLIN): telerehabilitation using an unactuated device based on serious games improves the upper limb function in chronic stroke

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Samantha G. Rozevink ◽  
Corry K. van der Sluis ◽  
Ainara Garzo ◽  
Thierry Keller ◽  
Juha M. Hijmans
Keyword(s):  
Quality Of Life ◽  
Upper Limb ◽  
Serious Games ◽  
Chronic Phase ◽  
Robotic Device ◽  
Limb Function ◽  
Upper Limb Function ◽  
Arm Rehabilitation ◽  
At Home

Abstract Background HoMEcare aRm rehabiLItatioN (MERLIN) is an unactuated version of the robotic device ArmAssist combined with a telecare platform. Stroke patients are able to train the upper limb function using serious games at home. The aim of this study is to investigate the effect of MERLIN training on the upper limb function of patients with unilateral upper limb paresis in the chronic phase of stroke (> 6 months post stroke). Methods Patients trained task specific serious games for three hours per week during six weeks using an unactuated version of a robotic device. Progress was monitored and game settings were tailored through telerehabilitation. Measurements were performed six weeks pre-intervention (T0), at the start (T1), end (T2) and six weeks post-intervention (T3). Primary outcome was the Wolf Motor Function Test (WMFT). Secondary outcomes were other arm function tests, quality of life, user satisfaction and motivation. Results Twelve patients were included, ten completed the training. From start of the intervention to six weeks follow up, WMFT improved significantly with 3.8 points (p = .006), which is also clinically relevant. No significant changes in quality of life were observed. Patients were overall satisfied with the usability of the device. Comfort and the robustness of the system need further improvements. Conclusion Patients in the chronic phase of stroke significantly improved their upper limb function with the MERLIN training at home. Trial registration This study is registered at the Netherlands Trial Register (NL7535). Registered 18–02-2019, https://www.trialregister.nl/trial/7535.

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