131I uptake in tumoral calcinosis in a patient on hemodialysis treated for thyroid cancer

Pulmonary metastases were found in 123 out of 840 patients with thyroid cancer between 1955-1977. 87 patients with pulmonary metastases of differentiated cancer were studied in detail, including an evaluation of prognostically important factors. In 66 of them, the induction of 131I uptake in metastases was attempted, in half of them successfully. Uptake was achieved more frequently in younger subjects, in papillary cancers and in patients with fine pulmonary metastases on chest films. Survival (not corrected for age) was evaluated 10 and 15 years following the diagnosis of thyroid cancer and was found to be 29,1 % and 12,2%, respectively. Significantly higher survival rates were seen in younger patients, in patients with the fine type of pulmonary metastases, in the absence of bone metastases and, particularly, in patients with induced 131I uptake in metastases. Papillary cancers were found to have higher survival rates in males and in young subjects only, in the whole group the survival rates were independent of either microscopic type or sex. It is believed that biologic behaviour of distant (pulmonary) metastases may be influenced by radioiodide therapy.

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Follicular Thyroid Cancer With Nose-Tip Metastasis and 131I Uptake

Clinical Nuclear Medicine ◽

10.1097/rlu.0000000000003072 ◽

2020 ◽

Vol 45 (10) ◽

pp. e441-e442

Author(s):

Shan-Fan Yao ◽

Chiang-Hsuan Lee ◽

Chuang-Hsin Chiu ◽

Yu-Ming Fan ◽

Wen-Sheng Huang

Keyword(s):

Thyroid Cancer ◽

Follicular Thyroid Cancer ◽

131I Uptake

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Small Activating RNA-Activated NIS Gene Promotes 131I Uptake and Inhibits Thyroid Cancer via AMPK/mTOR Pathway

Pathology - Research and Practice ◽

10.1016/j.prp.2021.153735 ◽

2021 ◽

pp. 153735

Author(s):

Li Jia ◽

Yan Chen ◽

Fukun Chen ◽

Juan Lv ◽

Yanling Li ◽

...

Keyword(s):

Thyroid Cancer ◽

Mtor Pathway ◽

131I Uptake ◽

Nis Gene

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Thoracic 131I Uptake After Previous Pneumonectomy in Patients Treated for Differentiated Thyroid Cancer

Clinical Nuclear Medicine ◽

10.1097/rlu.0b013e3182485146 ◽

2012 ◽

Vol 37 (6) ◽

pp. 587-590 ◽

Cited By ~ 3

Author(s):

Camila Nascimento ◽

Boumédiène Bridji ◽

Catherine Dejax ◽

Martin Schlumberger ◽

Sophie Leboulleux

Keyword(s):

Thyroid Cancer ◽

Differentiated Thyroid Cancer ◽

131I Uptake

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Recombinant Human TSH Increases Uptake and Effective Half-life of Radioiodine in Thyroid Hormone Secreting Metastases of Follicular Thyroid Cancer

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-0031-1299710 ◽

2012 ◽

Vol 120 (03) ◽

pp. 160-163 ◽

Cited By ~ 3

Author(s):

C. Schneider ◽

M. Dietlein ◽

W. Eschner ◽

M. Schmidt ◽

D. Kahraman ◽

...

Keyword(s):

Thyroid Cancer ◽

Thyroid Hormone ◽

Half Life ◽

World Wide ◽

Rare Condition ◽

Therapeutic Approaches ◽

Follicular Thyroid Cancer ◽

131I Uptake ◽

Tumor Entity ◽

First Time

AbstractFollicular thyroid cancer with thyroid hormone secreting metastases is an extremely rare condition, with only a few cases reported world-wide.We here present the case of a 64-year-old female patient affected by follicular thyroid cancer with extensive thyroid hormone secreting metastases leading to TSH-suppression.We have also summarized the relevant diagnostic and therapeutic approaches and describe, for the first time, the effects of rhTSH-application in this rare tumor entity.In this patient, we found that rhTSH increased 131I-uptake into the thyroid hormone secreting metastases and prolonged the effective half-life of 131I. These effects of rhTSH should be considered when fixed activities of 131I are prescribed.

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