scholarly journals Assessment of oral health in elderly patients with dementia by measuring volatile sulfur compounds and its relationship with pneumonia development: A pilot study

Author(s):  
Satoru Koga ◽  
Takahiro Takazono ◽  
Takumi Serita ◽  
Nobuyuki Ashizawa ◽  
Tatsuro Hirayama ◽  
...  
2020 ◽  
Vol 98 (9) ◽  
Author(s):  
Meredith Q Carroll ◽  
Patricia M Oba ◽  
Kelly M Sieja ◽  
Celeste Alexander ◽  
Lynn Lye ◽  
...  

Abstract Periodontal disease (PD) is the most common clinical condition occurring in adult dogs. The objective of this study was to evaluate the benefits of daily dental chew administration on oral health outcomes in adult dogs. Twelve adult (mean age = 5.31 ± 1.08 yr; mean BW = 13.12 ± 1.39 kg) female beagle dogs were used in a replicated 4 × 4 Latin square design consisting of 28-d periods. On day 0 of each period, teeth were cleaned by a veterinary dentist blinded to treatments. Teeth then were scored for plaque, calculus, and gingivitis by the same veterinary dentist on day 28 of each period. Breath samples were measured for malodor (volatile sulfur compounds) on days 1, 7, 14, 21, and 27 of each period. All dogs consumed the same commercial dry diet throughout the study. Control dogs were offered the diet only (CT), while treatment groups received the diet plus one of three dental chews. Two novel chews (Bones & Chews Dental Treats [BC]; Chewy, Inc., Dania Beach, FL and Dr. Lyon’s Grain-Free Dental Treats [DL]; Dr. Lyon’s, LLC, Dania Beach, FL) and a leading brand chew (Greenies Dental Treats [GR]; Mars Petcare US, Franklin, TN) were tested. Each day, one chew was provided 4 h after mealtime. All tooth scoring data were analyzed using the Mixed Models procedure of SAS (version 9.4; SAS Institute, Cary, NC). Halimeter data were analyzed using repeated measures using the Mixed Models procedure of SAS and testing for differences due to treatment, time, and treatment * time interaction. Data are reported as LS means ± SEM with statistical significance set at P < 0.05. DL performed at the same level as the leading brand, GR, as both resulted in lower (P < 0.05) plaque coverage and thickness scores, calculus coverage scores, and day 27 volatile sulfur concentrations compared with CT. Additionally, DL reduced (P < 0.05) volatile sulfur compounds on day 14 when compared with CT. BC reduced (P < 0.05) calculus coverage and day 27 volatile sulfur concentrations compared with CT. Our results suggest that the dental chews tested in this study may help slow the development and/or progression of PD in dogs.


2020 ◽  
Vol 58 (3) ◽  
pp. 212-215
Author(s):  
Takahiro Takazono ◽  
Yoshifumi Imamura ◽  
Masayasu Kitamura ◽  
Reiko Furugen ◽  
Tatsuro Hirayama ◽  
...  

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 149
Author(s):  
Noura A. AlMadhi ◽  
Ayman M. Sulimany ◽  
Hamad A. Alzoman ◽  
Omar A. Bawazir

Interventions and management modalities of pediatric halitosis have been suggested in the literature, however, the effect of full mouth rehabilitation (FMR) under general anesthesia (GA) on pediatric halitosis was not reported. Therefore, the present study was conducted to investigate parents’ perceptions of their child’s halitosis before and after FMR under GA; and to evaluate the effect of FMR on clinical halitosis. Fifty-seven children between 3–8 years old, scheduled for FMR under GA, were included after satisfying the inclusion criteria and upon parental consent. Parents’ perception of halitosis in their children was evaluated using a standardized questionnaire and a breath sample was collected to assess the level of volatile sulfur compounds (VSCs) using OralChromaTM before and after FMR under GA. Sixty percent (n = 34) of the parents perceived halitosis in their children before FMR and about 80% (n = 27) of them reported improvement in halitosis after FMR. Clinical halitosis was detected in 84.2% (n = 48) of the sample before treatment. A statistically significant reduction in halitosis was found in 56.3% (n = 27) of the children after treatment (p < 0.001). In conclusion, majority of parents perceived an absence or reduction of halitosis in their children following FMR and significant improvement of clinical halitosis.


2021 ◽  
Vol 7 (6) ◽  
pp. 465
Author(s):  
Takahito Toyotome ◽  
Masahiko Takino ◽  
Masahiro Takaya ◽  
Maki Yahiro ◽  
Katsuhiko Kamei

Schizophyllum commune is a causative agent of allergic bronchopulmonary mycosis, allergic fungal rhinosinusitis, and basidiomycosis. Diagnosis of these diseases remains difficult because no commercially available tool exists to identify the pathogen. Unique volatile organic compounds produced by a pathogen might be useful for non-invasive diagnosis. Here, we explored microbial volatile organic compounds produced by S. commune. Volatile sulfur compounds, dimethyl disulfide (48 of 49 strains) and methyl ethyl disulfide (49 of 49 strains), diethyl disulfide (34 of 49 strains), dimethyl trisulfide (40 of 49 strains), and dimethyl tetrasulfide (32 of 49 strains) were detected from headspace air in S. commune cultured vials. Every S. commune strain produced at least one volatile sulfur compound analyzed in this study. Those volatile sulfur compounds were not detected from the cultures of Aspergillus spp. (A. fumigatus, A. flavus, A. niger, and A. terreus), which are other major causative agents of allergic bronchopulmonary mycosis. The last, we examined H2S detection using lead acetate paper. Headspace air from S. commune rapidly turned the lead acetate paper black. These results suggest that those volatile sulfur compounds are potent targets for the diagnosis of S. commune and infectious diseases.


1978 ◽  
Vol 85 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Kaji Hiroshi ◽  
Hisamura Masaya ◽  
Saito Nariyoshi ◽  
Murao Makoto

Author(s):  
Shinjiro Koshimune ◽  
Shuji Awano ◽  
Kenjiro Gohara ◽  
Eriko Kurihara ◽  
Toshihiro Ansai ◽  
...  

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