scholarly journals Correlation of the modified Medical Research Council dyspnea scale with airway structure assessed by three-dimensional CT in patients with chronic obstructive pulmonary disease

2019 ◽  
Vol 146 ◽  
pp. 76-80 ◽  
Author(s):  
Hideki Yasui ◽  
Naoki Inui ◽  
Masato Karayama ◽  
Kazutaka Mori ◽  
Hironao Hozumi ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Medical Research ◽  
Pulmonary Disease ◽  
Research Council ◽  
Medical Research Council ◽  
Three Dimensional ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

scholarly journals Hubungan Antara Hitung Jenis Leukosit dengan Derajat Penyakit Paru Obstruktif Kronik Berdasarkan Gejala Klinis dan Gold 2019 pada Pasien Penyakit Paru Obstruktif Kronik Stabil di Rumah Sakit Islam Jakarta Sukapura

2020 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Nayla Sa’adah Alawiyah ◽  
Muhammad Fachri
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Medical Research ◽  
Pulmonary Disease ◽  
Research Council ◽  
Medical Research Council ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Global Initiative

Latar belakang: Penyakit Paru Obstruktif Kronik (PPOK) merupakan penyakit tidak menular yang menjadi salah satu masalah kesehatan di Indonesia diperkirakan terdapat 4,8 juta orang dengan prevalensi 56%. Tujuan: tujuan penelitian ini untuk mengetahui hubungan antara hitung jenis leukosit dengan derajat PPOK berdasarkan gejala klinis dan PPOK GOLD 2019 pada pasien PPOK stabil di Rumah Sakit Islam Jakarta Sukapura periode September 2018 – September 2019. Metode: studi ini merupakan penelitian kuantitatif dengan metode deskriptif analitik. Desain penelitian yang digunakan yaitu cross sectional. Teknik pengambilan sampel dalam penelitian ini yaitu teknik total sampling. Jumlah pasien PPOK stabil yang diteliti sebanyak 35 pasien. Penilaian gejala pada pasien PPOK menurut Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) 2019 dapat menggunakan kuesioner yang sudah divalidasi yaitu COPD Assesment Test/CAT dan Modified Medical Research Council/MMRC. Hasil: Hasil pemeriksaan hitung jenis leukosit terbanyak memiliki nilai eosinofil normal, nilai basofil normal, nilai neutrofil meningkat, nilai monosit normal, dan nilai limfosit normal. Kesimpulan: hasil penelitian menunjukkan kecenderungan peningkatan nilai leukosit pada setiap derajat PPOK, namun secara statistik tidak terdapat hubungan yang signifikan antara hitung jenis leukosit dengan derajat PPOK berdasarkan gejala klinis dan GOLD 2019 pada pasien PPOK stabil di RSIJ Sukapura.

scholarly journals Confirmatory Evaluation of the Modified Medical Research Council Questionnaire for Assessment of Dyspnea in Patients with Chronic Obstructive Pulmonary Disease in Portugal

2021 ◽  
Vol 34 (13) ◽  
Author(s):  
Soraia Ribeiro ◽  
Carlos Seiça Cardoso ◽  
Margarida Valério ◽  
João Machado ◽  
José Costa ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Medical Research ◽  
Pulmonary Disease ◽  
Research Council ◽  
Medical Research Council ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Language Version ◽  
British Medical Research Council ◽  
Kappa Agreement

Introduction: The Modified British Medical Research Council Questionnaire is considered an adequate and simple measure of breathlessness in chronic obstructive pulmonary disease. It is widely used in clinical practice in Portugal, but it still lacks confirmatory evaluation for the Portuguese setting. The aim of this study was to perform a cultural adaptation and validation of the Modified British Medical Research Council Questionnaire so that its most suitable version can be made available to researchers and clinicians in Portugal.Material and Methods: We performed a cross-sectional descriptive study involving patients with chronic obstructive pulmonary disease aged 40 years or older. We applied the Modified British Medical Research Council Questionnaire and the previously validated Portuguese-language version of the clinical questionnaire for chronic obstructive pulmonary disease between January and June 2019. We determined the agreement between the two questionnaires with kappa agreement, with a 95% confidence interval, and we used Spearman correlation to find a correlation between two scores.Results: The study included 65 patients managed in a hospital pulmonology clinic (aged 68 ± 7 years; with predicted FEV1 of 49.86% ± 16.5%). The Modified British Medical Research Council scale correlated significantly with all the domains and the overall score of the clinical questionnaire for chronic obstructive pulmonary disease (0.46 < r < 0.68; p < 0.001). In bilingual patients, interclass correlation coefficient was 0.912 (p < 0.001).Discussion: Our study showed that the Portuguese-language version of the Modified British Medical Research Council Questionnaire is feasible and externally valid when compared with a traditional and previously validated instrument.Conclusion: The Portuguese version of the Modified British Medical Research Council Questionnaire is a valid instrument for measurement of breathlessness in chronic obstructive pulmonary disease.

scholarly journals Sex-related differences in bronchial parameters and pulmonary function test results in patients with chronic obstructive pulmonary disease based on three-dimensional quantitative computed tomography

2017 ◽  
Vol 46 (1) ◽  
pp. 135-142 ◽  
Author(s):  
Yan Li ◽  
Yong-liang Dai ◽  
Nan Yu ◽  
You-min Guo
Keyword(s):  
Computed Tomography ◽  
Chronic Obstructive Pulmonary Disease ◽  
Smoking Cessation ◽  
Pulmonary Function ◽  
Pulmonary Disease ◽  
Quantitative Computed Tomography ◽  
Three Dimensional ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

Objective This study was performed to evaluate the effect of sex on bronchial parameters and the predicted forced expiratory volume in 1 s expressed as a percentage of the forced vital capacity (FEV1% pred) on pulmonary function testing. Methods The data of 359 patients with chronic obstructive pulmonary disease (COPD) with available FEV1% pred and computed tomography (CT) images were retrospectively reviewed. FACT-Digital lung TM software (DeXin, Xi’an, China) was used to perform fully automated three-dimensional CT quantitative measurements of the bronchi. Generation 5 to 7 bronchi were measured, and the parameters analyzed were the lumen diameter (LD), wall thickness (WT), lumen area (LA), and WA% [WA / (WA + LA) × 100%]. Results In the smoking, smoking cessation, and nonsmoking groups, women had a significantly larger WA% and smaller LD, WT, and LA than men. The FEV1% pred was significantly lower in women than men in the smoking and smoking cessation groups. The FEV1% pred was significantly higher in women than men in the nonsmoking group. Conclusion Sex-related differences may partially explain why smoking women experience more severe pulmonary function impairment than men among patients with COPD.

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