New insights on the spectrophotometric determination of melatonin pKa values and melatonin-βCD inclusion complex formation constant

2018 ◽  
Vol 190 ◽  
pp. 442-449 ◽  
Author(s):  
A. Zafra-Roldán ◽  
S. Corona-Avendaño ◽  
R. Montes-Sánchez ◽  
M. Palomar-Pardavé ◽  
M. Romero-Romo ◽  
...  
Keyword(s):  
Complex Formation ◽  
Inclusion Complex ◽  
Spectrophotometric Determination ◽  
Formation Constant ◽  
Complex Formation Constant ◽  
Inclusion Complex Formation ◽  
Pka Values

scholarly journals A Comparative Study of the Inclusion Complexes of 2-[5'-benzylidene-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole and 2-[5'-(p-N,N-dimethylamino- benzylidene)-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole withβ-Cyclodextrin

2011 ◽  
Vol 8 (3) ◽  
pp. 1030-1037
Author(s):  
S. Panda ◽  
S. K. Dash
Keyword(s):  
Complex Formation ◽  
Inclusion Complex ◽  
Inclusion Complexes ◽  
Inclusion Complex Formation ◽  
Polar Medium ◽  
Antibacterial And Antifungal Activities ◽  
Before And After ◽  
The Stability ◽  
Antibacterial And Antifungal

The compounds 2-[5'-benzylidene-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole and 2-[5'-(p-N,N-dimethylamino- benzylidene)-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole have been synthesized in their purest forms starting from 2-aminobenzothiazole. The inclusion complexes of the above compounds have been prepared with β-cyclodextrin to increase their solubility and bioaccessibility in polar medium. The formation of inclusion complexes have been ascertained by study of spectral characteristic before and after inclusion complex formation. The stability of inclusion complexes and nature of interaction between the host and guest are known from the determination of thermodynamic parameters. Further the antibacterial and antifungal activities of the compounds are determined which is found to increase significantly after inclusion complex formation

Study on the Determination of Carbendazim in Water and Vegetable Samples

2014 ◽  
Vol 955-959 ◽  
pp. 1351-1354 ◽  
Author(s):  
Ji Cheng Xu ◽  
Xin Shan Rong ◽  
Ting Tian ◽  
Feng Xian Qiu
Keyword(s):  
Complex Formation ◽  
Inclusion Complex ◽  
Fluorescence Intensity ◽  
Limit Of Detection ◽  
Sensitivity Factor ◽  
Inclusion Complex Formation ◽  
Cyclodextrin Derivative ◽  
Vegetable Samples ◽  
Fruit Samples

The host-guest inclusion complex formation between 3, 3’-benzidine/β-cyclodextrin derivative (BDCD) and pesticide carbendazim was studied and characterized by TEM and XRD. The result showed that inclusion complex had hydrophobic small-molecule fluorophores. The fluorescence titration was performed to calculate binding constant, sensitivity factor and limit of detection of the resulting complex. Based on the enhancement of the fluorescence intensity of carbendazim produced throught complex formation, a new sensitive method for the determination of carbendazim was established. A linear relationship was obtained between the fluorescence intensity and carbendazim concentration in the range of 3.57 and 17.83 μmol/L. The correlation coefficient, the lowest limit of detection and RSD were 0.9916, 15.51 nmol/L and 2.13%, respectively. This method has better anti-interference ability and stability. The proposed method have been successfully applied to the determination of carbendazim pesticide residues in water, vegetable and fruit samples with satisfactory results, recoveries in the range of 87.56 % to 104.04 % were obtained.

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