FIRST-EPISODE PSYCHOSIS: GENDER DIFFERENCES IN SUBSTANCE USE

2010 ◽  
Vol 117 (2-3) ◽  
pp. 424-425
Author(s):  
Luis San ◽  
Belen Arranz ◽  
Victor Perez ◽  
Bernardo Sanchez ◽  
Montse Dolz ◽  
...  
Keyword(s):  
Gender Differences ◽  
Substance Use ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis

scholarly journals Gender differences in clinical presentation and illicit substance use during first episode psychosis: a natural language processing, electronic case register study

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e042949
Author(s):  
Jessica Irving ◽  
Craig Colling ◽  
Hitesh Shetty ◽  
Megan Pritchard ◽  
Robert Stewart ◽  
...  
Keyword(s):  
Gender Differences ◽  
Substance Use ◽  
Language Processing ◽  
Negative Symptoms ◽  
Clinical Presentation ◽  
First Episode Psychosis ◽  
First Episode ◽  
Illicit Substance ◽  
Illicit Substance Use ◽  
Episode Psychosis

ObjectiveTo determine whether gender differences in symptom presentation at first episode psychosis (FEP) remain even when controlling for substance use, age and ethnicity, using natural language processing applied to electronic health records (EHRs).Design, setting and participantsData were extracted from EHRs of 3350 people (62% male patients) who had presented to the South London and Maudsley NHS Trust with a FEP between 1 April 2007 and 31 March 2017. Logistic regression was used to examine gender differences in the presentation of positive, negative, depressive, mania and disorganisation symptoms.Exposure(s) (for observational studies)Gender (male vs female).Main outcome(s) and measure(s)Presence of positive, negative, depressive, mania and disorganisation symptoms at initial clinical presentation.ResultsEight symptoms were significantly more prevalent in men (poverty of thought, negative symptoms, social withdrawal, poverty of speech, aggression, grandiosity, paranoia and agitation). Conversely, tearfulness, low energy, reduced appetite, low mood, pressured speech, mood instability, flight of ideas, guilt, mutism, insomnia, poor concentration, tangentiality and elation were more prevalent in women than men. Negative symptoms were more common among men (OR 1.85, 95% CI 1.33 to 2.62) and depressive and manic symptoms more common among women (OR 0.30, 95% CI 0.26 to 0.35). After adjustment for illicit substance use, the strength of associations between gender and negative, manic and depression symptoms increased, whereas gender differences in aggression, agitation, paranoia and grandiosity became insignificant.ConclusionsThere are clear gender differences in the clinical presentation of FEP. Our findings suggest that gender can have a substantial influence on the nature of clinical presentation in people with psychosis, and that this is only partly explained by exposure to illicit substance use.

Comorbidities in Patients with an At-risk Mental State and First Episode Psychosis

2017 ◽  
Vol 41 (S1) ◽  
pp. S198-S198 ◽  
Author(s):  
U. Heitz ◽  
J. Cherbuin ◽  
S. Menghini-Müller ◽  
L. Egloff ◽  
S. Ittig ◽  
...  
Keyword(s):  
Gender Differences ◽  
Substance Use ◽  
Anxiety Disorders ◽  
Substance Use Disorders ◽  
Mental State ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis ◽  
Axis I ◽  
At Risk Mental State

IntroductionNon-psychotic axis I diagnoses are highly prevalent in at-risk mental state (ARMS) and first episode psychosis (FEP) patients, the most common being affective and anxiety disorders. Few studies have examined differences between ARMS and FEP patients or gender effects regarding such diagnoses.ObjectiveTo examine current and lifetime comorbidities in ARMS and FEP patients. Furthermore, to examine gender differences, and differences between patients with (ARMS-T) and without later transition to psychosis (ARMS-NT).MethodsThis study was part of the Früherkennung von Psychosen (FePsy) study. Current and lifetime axis I comorbidities were assessed using the Structured Clinical Interview for DSM-IV (SCID-I).ResultsOne hundred and thirty-two ARMS and 98 FEP patients were included. Current comorbidities were present in 53.1% of FEP and 64.4% of ARMS patients, the most common being affective, anxiety and substance use disorders. Current affective disorders were significantly more common in ARMS than FEP. Lifetime comorbidities were diagnosed in 58.2% of FEP and 69.7% of ARMS patients, with significantly more affective and anxiety disorders in ARMS than FEP. Male FEP patients had more current and lifetime substance use disorders (across all substances) compared to female FEP. No differences emerged between ARMS-T and ARMS-NT.ConclusionsAs expected ARMS patients have many comorbidities, while clearly diagnosed FEP have less comorbidities. There were few gender differences in axis I comorbidities. Moreover, no differences between ARMS-T and NT emerged, suggesting that axis I comorbidities do not improve prediction of transition. Nevertheless, the high comorbidity prevalence is relevant for global functioning and clinical treatment.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Gender differences in response to metacognitive training in people with first-episode psychosis.

2020 ◽  
Vol 88 (6) ◽  
pp. 516-525 ◽  
Author(s):  
Miriam Salas-Sender ◽  
Raquel López-Carrilero ◽  
Ana Barajas ◽  
Esther Lorente-Rovira ◽  
Esther Pousa ◽  
...  
Keyword(s):  
Gender Differences ◽  
First Episode Psychosis ◽  
First Episode ◽  
Metacognitive Training ◽  
Episode Psychosis

scholarly journals Barriers and Facilitators That Influence Providers’ Ability to Educate, Monitor, and Treat Substance Use in First-Episode Psychosis Programs Using the Theoretical Domains Framework

2021 ◽  
pp. 104973232199344
Author(s):  
Oladunni Oluwoye ◽  
Elizabeth Fraser
Keyword(s):  
Substance Use ◽  
Behavior Change ◽  
Theoretical Domains Framework ◽  
First Episode Psychosis ◽  
Barriers And Facilitators ◽  
First Episode ◽  
Evidence Based ◽  
Behavior Change Techniques ◽  
Episode Psychosis ◽  
And Behavior

In this qualitative study, we explore providers’ experiences with addressing substance use among individuals with first-episode psychosis (FEP) enrolled in coordinated specialty care (CSC) programs. Three focus groups were conducted with 24 providers from CSC programs for FEP in Washington. Questions were focused on barriers and facilitators to addressing substance use using the Theoretical Domains Framework (TDF) as a guide. Thematic analysis was used to code all transcripts. Identified TDF domains were then mapped onto the COM-B (Capability, Opportunity, Motivation, Behavior) intervention functions and behavior change techniques. Seven theoretical domains were identified as the most relevant to addressing substance use: “Knowledge,” “Skills,” “Environmental Context and Resources,” “Social Influences,” “Social and Professional Role and Identity,” “Beliefs about Capabilities,” and “Reinforcement.” The use of the TDF provides a framework to explore barriers and facilitators for targeting substance use and suggestions for behavior change techniques when considering implementation of evidence-based strategies to enhance CSC models.

scholarly journals Introspective accuracy for substance use across a year of treatment for first episode psychosis

2021 ◽  
Vol 26 ◽  
pp. 100200
Author(s):  
Joshua E. Mervis ◽  
Jamie Fischer ◽  
Samuel E. Cooper ◽  
Andrew C. Deckert ◽  
Paul H. Lysaker ◽  
...  
Keyword(s):  
Substance Use ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis

scholarly journals Gender differences in suicidal behaviour in patients with first-episode psychosis

2013 ◽  
Vol 9 (4) ◽  
pp. 300-307 ◽  
Author(s):  
Gudrun Austad ◽  
Inge Joa ◽  
Jan Olav Johannessen ◽  
Tor Ketil Larsen
Keyword(s):  
Gender Differences ◽  
Suicidal Behaviour ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis

scholarly journals Are There Gender Differences in Social Cognition in First-Episode Psychosis?

Women ◽  
2021 ◽  
Vol 1 (4) ◽  
pp. 204-211
Author(s):  
Marina Verdaguer-Rodríguez ◽  
Raquel López-Carrilero ◽  
Marta Ferrer-Quintero ◽  
Helena García-Mieres ◽  
Luciana Díaz-Cutraro ◽  
...  
Keyword(s):  
Gender Differences ◽  
Social Cognition ◽  
Attributional Style ◽  
Social Cognitive ◽  
First Episode Psychosis ◽  
Test Theory ◽  
First Episode ◽  
Cognitive Domains ◽  
Episode Psychosis ◽  
The Social

The aim of this study was to explore gender differences in social cognition in a sample of first-episode psychosis (FEP). An observational descriptive study was performed with 191 individuals with FEP. Emotion perception was assessed using the Faces Test, theory of mind was assessed using the Hinting Task, and attributional style was assessed using the Internal, Personal and Situational Attributions Questionnaire. No gender differences were found in any of the social cognitive domains. Our results suggest that men and women with FEP achieve similar performances in social cognition. Therefore, targeting specific needs in social cognition regarding gender may not be required in early interventions for psychosis.

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