Are cognitive deficits observed in obstructive sleep apnea associated with cognitive complaints?

2013 ◽  
Vol 14 ◽  
pp. e131-e132
Author(s):  
M. Fortin ◽  
K. Gagnon ◽  
A. Baril ◽  
C. D’Aragon ◽  
J. Gagnon ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cognitive Deficits ◽  
Cognitive Complaints ◽  
Obstructive Sleep

scholarly journals Cognitive deficits in adults with obstructive sleep apnea compared to children and adolescents

2016 ◽  
Vol 124 (S1) ◽  
pp. 187-201 ◽  
Author(s):  
Krzysztof Krysta ◽  
Agnieszka Bratek ◽  
Karolina Zawada ◽  
Radosław Stepańczak
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Children And Adolescents ◽  
Cognitive Deficits ◽  
Obstructive Sleep

scholarly journals Executive function in patients with obstructive sleep apnea treated with continuous positive airway pressure

2010 ◽  
Vol 16 (6) ◽  
pp. 1077-1088 ◽  
Author(s):  
ESTHER YUET YING LAU ◽  
GAIL A. ESKES ◽  
DEBRA L. MORRISON ◽  
MALGORZATA RAJDA ◽  
KATHLEEN F. SPURR
Keyword(s):  
Working Memory ◽  
Obstructive Sleep Apnea ◽  
Executive Function ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Cognitive Deficits ◽  
Daytime Sleepiness ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Obstructive Sleep

AbstractObstructive sleep apnea (OSA) is characterized by disrupted breathing and hypoxemia during sleep, daytime sleepiness, and changes in cognition and mood. One important question is regarding the reversibility of cognitive deficits after treatment with continuous positive airway pressure (CPAP). Here, we report the outcomes of CPAP treatment as measured by tests of attention and executive function. Thirty-seven individuals with moderate to severe OSA and compliant on CPAP treatment were studied with working memory tasks, neuropsychological testing, and overnight polysomnographic sleep study and compared to 27 healthy controls. CPAP improved the respiratory disturbance index, minimum and mean oxygen saturation (SpO2), subjective sleep quality, and daytime sleepiness ratings compared to pre-treatment values. In terms of current neurocognitive function, treated individuals with OSA performed at a comparable level to controls on basic working memory storage functions but still showed a significant reduction on tests of working memory requiring the central executive. The OSA group also performed worse on neuropsychological measures of complex attention, executive function, and psychomotor speed. While CPAP is an effective treatment for OSA in terms of ameliorating breathing disruption and oxygen desaturation during sleep, as well as daytime sleepiness, some cognitive deficits may be more resistant to treatment. (JINS, 2010,16, 1077–1088.)

Brain Injury And Cognitive Deficits Reverse With Treatment Of Childhood Obstructive Sleep Apnea

2012 ◽  
Author(s):  
Ann C. Halbower ◽  
Jennifer Janusz ◽  
Mark Brown ◽  
John Strain ◽  
Norman Friedman ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Brain Injury ◽  
Sleep Apnea ◽  
Cognitive Deficits ◽  
Obstructive Sleep

Symptoms of obstructive sleep apnea are associated with less frequent exercise and worse subjective cognitive function across adulthood

SLEEP ◽  
2021 ◽  
Author(s):  
Miranda G Chappel-Farley ◽  
Bryce A Mander ◽  
Ariel B Neikrug ◽  
Annamarie Stehli ◽  
Bin Nan ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cognitive Function ◽  
Sleep Quality ◽  
Sleep Problems ◽  
Factor Scores ◽  
Cognitive Complaints ◽  
Exercise Frequency ◽  
Obstructive Sleep ◽  
The Relationship

Abstract Study Objectives To determine whether subjective measures of exercise and sleep are associated with cognitive complaints and whether exercise effects are mediated by sleep. Methods This study analyzed questionnaire data from adults (18-89) enrolled in a recruitment registry. The Cognitive Function Instrument (CFI) assessed cognitive complaints. Medical Outcomes Study Sleep Scale (MOS-SS) subscales and factor scores assessed sleep quality, daytime sleepiness, nighttime disturbance, and insomnia and OSA-like symptoms. Exercise frequency was defined as the weekly number of exercise sessions. Exercise frequency, MOS-SS subscales and factor scores were examined as predictors of CFI Score, adjusting for age, BMI, education, sex, cancer diagnosis, antidepressant usage, psychiatric conditions, and medical comorbidities. ANCOVA examined the relationship between sleep duration groups (short, mid-range, and long) and CFI Score, adjusting for covariates. Mediation by sleep in the exercise-CFI score relationship was tested. Results Data from 2,106 adults were analyzed. Exercise and MOS-SS subscales and factor scores were associated with CFI score. Higher Sleep Adequacy scores were associated with fewer cognitive complaints, whereas higher Sleep Somnolence, Sleep Disturbance, Sleep Problems Index I, Sleep Problems Index II, and factor scores were associated with more cognitive complaints. MOS-SS subscales and factor scores, except Sleep Disturbance and the insomnia factor score, mediated the association between exercise and cognitive complaints. Conclusions The relationship between exercise frequency and subjective cognitive performance is mediated by sleep. In particular, the mediation effect appears to be driven by symptoms possibly suggestive of obstructive sleep apnea which are negatively associated with exercise engagement, sleep quality, daytime sleepiness, and subjective cognitive performance.

Neuropsychological sequelae of obstructive sleep apnea-hypopnea syndrome: A critical review

2004 ◽  
Vol 10 (5) ◽  
pp. 772-785 ◽  
Author(s):  
MARK S. ALOIA ◽  
J. TODD ARNEDT ◽  
JENNIFER D. DAVIS ◽  
RAINE L. RIGGS ◽  
DESIREE BYRD
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cognitive Functioning ◽  
Cognitive Deficits ◽  
Neuropsychological Sequelae ◽  
Cognitive Domains ◽  
Patient Reports ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome ◽  
The Brain

Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a well-recognized clinical sleep disorder that results in chronically fragmented sleep and recurrent hypoxemia. The primary daytime sequelae of the disorder include patient reports of excessive daytime sleepiness, depression, and attention and concentration problems. It has been well established that OSAHS negatively impacts certain aspects of cognitive functioning. The primary goals of this article are to (1) clarify the pattern of cognitive deficits that are specific to OSAHS; (2) identify the specific cognitive domains that improve with treatment; and (3) elucidate the possible mechanisms of cognitive dysfunction in OSAHS. At the conclusion of the paper, we propose a potential neurofunctional theory to account for the etiology of cognitive deficits in OSAHS. Thirty-seven peer-reviewed articles were selected for this review. In general, findings were equivocal for most cognitive domains. Treatment, however, was noted to improve attention/vigilance in most studies and consistently did not improve constructional abilities or psychomotor functioning. The results are discussed in the context of a neurofunctional theory for the effects of OSAHS on the brain. (JINS, 2004,10, 772–785.)

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