Brain Injury And Cognitive Deficits Reverse With Treatment Of Childhood Obstructive Sleep Apnea

Author(s):  
Ann C. Halbower ◽  
Jennifer Janusz ◽  
Mark Brown ◽  
John Strain ◽  
Norman Friedman ◽  
...  
2013 ◽  
Vol 14 ◽  
pp. e131-e132
Author(s):  
M. Fortin ◽  
K. Gagnon ◽  
A. Baril ◽  
C. D’Aragon ◽  
J. Gagnon ◽  
...  

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A314-A315
Author(s):  
Bridget Cotner ◽  
Risa Nakase-Richardson ◽  
Becky Gius ◽  
Lauren Fournier ◽  
Alexa Watach ◽  
...  

Abstract Introduction Obstructive Sleep Apnea (OSA) is prevalent after moderate to severe traumatic brain injury (TBI) and may diminish recovery when left untreated. Despite the demonstrated importance of treating OSA following TBI, assessment for OSA during or soon after inpatient rehabilitation for TBI is limited. Little is known about barriers to implementing OSA screening and early diagnosis during inpatient rehabilitation thus hindering the translation of evidence-based OSA assessment procedures into clinical practice and potentially delaying necessary OSA treatment. The current analysis explored facilitators and barriers to implementing OSA screening tools in an inpatient rehabilitation setting from the perspectives of end user stakeholders. Methods Patients, families, industry, clinical providers and administrators participated in a two-day meeting following completion of a diagnostic clinical trial of OSA screening and diagnostic tools during inpatient rehabilitation. Stakeholders were provided with open ended questions generated by study investigators and given the opportunity to respond on paper or a “graffiti wall” (i.e., white board). Example questions include “What are the greatest needs of the healthcare system related to sleep apnea and TBI?” and “What are the key things we need to consider to move results into real-world practice?” Qualitative content analyses using a rapid matrix approach were conducted from stakeholder feedback obtained during the two-day meeting, which included a guided review of emerging OSA research and discussion of potential implementation barriers of OSA assessment during inpatient rehabilitation. Results Improved screening and treatment practices for OSA were the greatest needs identified. To meet these needs, stakeholders identified the importance of improving patient, family, and staff understanding of OSA (e.g., health literacy) and other sleep disorders through education; inpatient rehabilitation access to resources (technology; sleep providers); and reimbursement for additional inpatient procedures. Conclusion Although treatment of OSA is crucial for recovery during inpatient rehabilitation following TBI, barriers to earlier recognition, diagnosis, and treatment of OSA exists across several different domains, including education, resources, and funding policies. Findings support future implementation efforts to translate evidence-based care into practice to improve patient outcomes. Support (if any) PCORI-NCT03033901


PM&R ◽  
2009 ◽  
Vol 1 (10) ◽  
pp. 977-979 ◽  
Author(s):  
Jaspal R. Singh ◽  
Miriam Segal ◽  
Richard Malone ◽  
Mohammed Zubair

PLoS Medicine ◽  
2006 ◽  
Vol 3 (8) ◽  
pp. e301 ◽  
Author(s):  
Ann C Halbower ◽  
Mahaveer Degaonkar ◽  
Peter B Barker ◽  
Christopher J Earley ◽  
Carole L Marcus ◽  
...  

2016 ◽  
Vol 124 (S1) ◽  
pp. 187-201 ◽  
Author(s):  
Krzysztof Krysta ◽  
Agnieszka Bratek ◽  
Karolina Zawada ◽  
Radosław Stepańczak

2010 ◽  
Vol 16 (6) ◽  
pp. 1077-1088 ◽  
Author(s):  
ESTHER YUET YING LAU ◽  
GAIL A. ESKES ◽  
DEBRA L. MORRISON ◽  
MALGORZATA RAJDA ◽  
KATHLEEN F. SPURR

AbstractObstructive sleep apnea (OSA) is characterized by disrupted breathing and hypoxemia during sleep, daytime sleepiness, and changes in cognition and mood. One important question is regarding the reversibility of cognitive deficits after treatment with continuous positive airway pressure (CPAP). Here, we report the outcomes of CPAP treatment as measured by tests of attention and executive function. Thirty-seven individuals with moderate to severe OSA and compliant on CPAP treatment were studied with working memory tasks, neuropsychological testing, and overnight polysomnographic sleep study and compared to 27 healthy controls. CPAP improved the respiratory disturbance index, minimum and mean oxygen saturation (SpO2), subjective sleep quality, and daytime sleepiness ratings compared to pre-treatment values. In terms of current neurocognitive function, treated individuals with OSA performed at a comparable level to controls on basic working memory storage functions but still showed a significant reduction on tests of working memory requiring the central executive. The OSA group also performed worse on neuropsychological measures of complex attention, executive function, and psychomotor speed. While CPAP is an effective treatment for OSA in terms of ameliorating breathing disruption and oxygen desaturation during sleep, as well as daytime sleepiness, some cognitive deficits may be more resistant to treatment. (JINS, 2010,16, 1077–1088.)


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