Automated slow wave sleep disruption in middle-aged adults

2015 ◽  
Vol 16 ◽  
pp. S16
Author(s):  
S. Ooms ◽  
J. Zempel ◽  
D. Holtzman ◽  
Y. Ju
Keyword(s):  
Slow Wave ◽  
Slow Wave Sleep ◽  
Sleep Disruption ◽  
Middle Aged ◽  
Middle Aged Adults

scholarly journals Effect of Slow Wave Sleep Disruption on Metabolic Parameters in Adolescents

SLEEP ◽  
2016 ◽  
Vol 39 (8) ◽  
pp. 1591-1599 ◽  
Author(s):  
Natalie D. Shaw ◽  
Andrew W. McHill ◽  
Michele Schiavon ◽  
Tairmae Kangarloo ◽  
Piotr W. Mankowski ◽  
...  
Keyword(s):  
Slow Wave ◽  
Slow Wave Sleep ◽  
Metabolic Parameters ◽  
Sleep Disruption

scholarly journals Targeted memory reactivation of face-name learning depends on ample and undisturbed slow-wave sleep

2022 ◽  
Vol 7 (1) ◽  
Author(s):  
Nathan W. Whitmore ◽  
Adrianna M. Bassard ◽  
Ken A. Paller
Keyword(s):  
Slow Wave ◽  
Slow Wave Sleep ◽  
Social Contexts ◽  
Background Music ◽  
Sleep Disruption ◽  
Memory Functions ◽  
Face Memory ◽  
Memory Reactivation ◽  
Two Factors ◽  
Daytime Nap

AbstractFace memory, including the ability to recall a person’s name, is of major importance in social contexts. Like many other memory functions, it may rely on sleep. We investigated whether targeted memory reactivation during sleep could improve associative and perceptual aspects of face memory. Participants studied 80 face-name pairs, and then a subset of spoken names with associated background music was presented unobtrusively during a daytime nap. This manipulation preferentially improved name recall and face recognition for those reactivated face-name pairs, as modulated by two factors related to sleep quality; memory benefits were positively correlated with the duration of stage N3 sleep (slow-wave sleep) and negatively correlated with measures of sleep disruption. We conclude that (a) reactivation of specific face-name memories during sleep can strengthen these associations and the constituent memories, and that (b) the effectiveness of this reactivation depends on uninterrupted N3 sleep.

scholarly journals The role of non-rapid eye movement slow-wave activity in prefrontal metabolism across young and middle-aged adults

2016 ◽  
Vol 25 (3) ◽  
pp. 296-306 ◽  
Author(s):  
Kristine A. Wilckens ◽  
Howard J. Aizenstein ◽  
Eric A. Nofzinger ◽  
Jeffrey A. James ◽  
Brant P. Hasler ◽  
...  
Keyword(s):  
Eye Movement ◽  
Slow Wave ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Rapid Eye Movement ◽  
Middle Aged ◽  
Middle Aged Adults

Comparison of automated REM and slow-wave sleep analysis in young and middle-aged depressed subjects

1986 ◽  
Vol 21 (2) ◽  
pp. 189-200 ◽  
Author(s):  
David J. Kupfer ◽  
Charles F. Reynolds ◽  
Richard F. Ulrich ◽  
Victoria J. Grochocinski
Keyword(s):  
Slow Wave ◽  
Slow Wave Sleep ◽  
Middle Aged ◽  
Sleep Analysis

scholarly journals Targeted Memory Reactivation of Face-Name Learning Depends on Ample and Undisturbed Slow-Wave Sleep

2021 ◽  
Author(s):  
Nathan Whitmore ◽  
Adrianna M. Bassard ◽  
Ken A. Paller
Keyword(s):  
Slow Wave ◽  
Slow Wave Sleep ◽  
Sleep Disruption ◽  
Face Memory ◽  
Memory Reactivation ◽  
Two Factors ◽  
Daytime Nap ◽  
Electroencephalographic Activity ◽  
Familiar Person

AbstractFace memory, including the ability to recall the name of a familiar person, is often crucial in social interactions, and like many other memory functions, it may rely on sleep. We investigated whether targeted memory reactivation during sleep could improve associative and perceptual aspects of face memory. Participants studied 80 face-name pairs, and then a subset of spoken names was presented unobtrusively during a daytime nap. This reactivation preferentially improved recall for those face-name pairs, as modulated by two factors related to sleep quality. That is, the memory benefit was positively correlated with the duration of stage N3 sleep (slow-wave sleep) and with the extent to which cues presented during SWS did not produce a sleep disruption indexed by increased alpha-band electroencephalographic activity in the 5 seconds after a cue. Follow-up analyses showed that a memory benefit from presenting spoken names during sleep was evident in participants with high amounts of SWS or with low amounts of sleep disruption. We conclude that sleep reactivation can strengthen memory for specific face-name associations and that the effectiveness of reactivation depends on uninterrupted N3 sleep.

scholarly journals Acoustic slow wave sleep enhancement via a novel, automated device improves executive function in middle-aged men

SLEEP ◽  
2019 ◽  
Author(s):  
Charmaine Diep ◽  
Suzanne Ftouni ◽  
Jessica E Manousakis ◽  
Christian L Nicholas ◽  
Sean P A Drummond ◽  
...  
Keyword(s):  
Executive Function ◽  
Cognitive Function ◽  
Slow Wave ◽  
Slow Wave Sleep ◽  
Healthy Adult ◽  
Acoustic Stimulation ◽  
Trial Registration ◽  
Cognitive Capacity ◽  
Adult Males ◽  
Middle Aged

Abstract Study Objectives As slow-wave activity (SWA) is critical for cognition, SWA-enhancing technologies provide an exciting opportunity to improve cognitive function. We focus on improving cognitive function beyond sleep-dependent memory consolidation, using an automated device, and in middle-aged adults, who have depleted SWA yet a critical need for maximal cognitive capacity in work environments. Methods Twenty-four healthy adult males aged 35–48 years participated in a randomized, double-blind, cross-over study. Participants wore an automated acoustic stimulation device that monitored real-time sleep EEG. Following an adaptation night, participants were exposed to either acoustic tones delivered on the up phase of the slow-wave (STIM) or inaudible “tones” during equivalent periods of stimulation (SHAM). An executive function test battery was administered after the experimental night. Results STIM resulted in an increase in delta (0.5–4 Hz) activity across the full-night spectra, with enhancement being maximal at 1 Hz. SWA was higher for STIM relative to SHAM. Although no group differences were observed in any cognitive outcomes, due to large individual differences in SWA enhancement, higher SWA responders showed significantly improved verbal fluency and working memory compared with nonresponders. Significant positive associations were found between SWA enhancement and improvement in these executive function outcomes. Conclusions Our study suggests that (1) an automated acoustic device enhances SWA; (2) SWA enhancement improves executive function; (3) SWA enhancement in middle-aged men may be an important therapeutic target for enhancing cognitive function; and (4) there is a need to examine interindividual responses to acoustic stimulation and its effect on subsequent cognitive function. Clinical trial registration This study has been registered with the Australian New Zealand Clinical Trials Registry. “The efficacy of acoustic tones in slow-wave sleep enhancement and cognitive function in healthy adult males”. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=371548&isReview=true Registration ACTRN12617000399392.

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