Direct and sensitive determination of trypsin in human urine using a water-soluble signaling fluorescent molecularly imprinted polymer nanoprobe

2018 ◽  
Vol 258 ◽  
pp. 10-17 ◽  
Author(s):  
Jingjing Xu ◽  
Elise Prost ◽  
Karsten Haupt ◽  
Bernadette Tse Sum Bui
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Human Urine ◽  
Water Soluble ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Sensitive Determination

scholarly journals Correction: Synthesis of a monodisperse well-defined core–shell magnetic molecularly-imprinted polymer prior to LC-MS/MS for fast and sensitive determination of mycotoxin residues in rice

2019 ◽  
Vol 11 (25) ◽  
pp. 3269-3270
Author(s):  
Sheng-Dong Pan ◽  
Mei-Jun Ye ◽  
Guo-Sheng Gao ◽  
Qian He ◽  
Li Wang ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Core Shell ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Magnetic Molecularly Imprinted Polymer ◽  
Sensitive Determination

Correction for ‘Synthesis of a monodisperse well-defined core–shell magnetic molecularly-imprinted polymer prior to LC-MS/MS for fast and sensitive determination of mycotoxin residues in rice’ by Sheng-Dong Pan et al., Anal. Methods, 2017, 9, 5281–5292.

Sensitive and selective “signal-off” electrochemiluminescence sensing for prostate-specific antigen based on aptamer and molecularly imprinted polymer

The Analyst ◽  
2021 ◽  
Author(s):  
Yuanyuan Wang ◽  
Xianwen Kan
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Molecularly Imprinted Polymer ◽  
Specific Antigen ◽  
Imprinted Polymer ◽  
Molecular Biomarker ◽  
Molecularly Imprinted ◽  
Real Samples ◽  
Sensitive Determination

Specific and sensitive determination of prostate-specific antigen (PSA) in complex real samples holds significant importance since it is an effective molecular biomarker for the clinical diagnosis of prostate cancer. Herein,...

Solid-phase extraction using molecularly imprinted polymer for determination of ochratoxin A in human urine

2015 ◽  
Vol 8 (1) ◽  
pp. 37-43 ◽  
Author(s):  
L. Xie ◽  
P. Sheng ◽  
W. Kong ◽  
X. Zhao ◽  
Z. Ou-Yang ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Ochratoxin A ◽  
Molecularly Imprinted Polymer ◽  
Human Urine ◽  
Solid Phase ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

A rapid, selective and reliable sample preparation technique employing solid-phase extraction (SPE) based on molecularly imprinted polymer (MIP) for the determination of ochratoxin A (OTA) in human urine was described. After sample adjustment to pH 2.5 with 0.1 M HCl, the urine sample was loaded onto the MIP-SPE column, and after a wash step, OTA was eluted for measurement by ultra-high performance liquid chromatography coupled with fluorescence detection. Key parameters which affected the MIP-SPE extraction efficiency were optimized as was the detection method. Under the optimised conditions, the limits of detection and quantification for OTA in urine were 0.2 ng/ml and 0.6 ng/ml, respectively. The recoveries for OTA in urine, spiked at the 0.6, 6.0 and 60 ng/ml levels, ranged from 92.0 to 98.9%. Sixty urine samples were analysed, of which four were found to contain OTA at concentrations ranging from 0.022 to 0.083 ng/ml; the positive results were confirmed by liquid chromatography coupled with tandem mass spectrometry. OTA determination in urine is a good indicator for human exposure to the mycotoxin, and this is the first report on OTA contamination in Chinese people.

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