Highly sensitive label-free detection of analytes at different scales using uniform graphene-nanopyramids hybrid SERS system

2022 ◽  
Vol 354 ◽  
pp. 131205
Author(s):  
Heping Wu ◽  
Gang Niu ◽  
Wei Ren ◽  
Luyue Jiang ◽  
Jinyan Zhao ◽  
...  
Keyword(s):  
Label Free ◽  
Highly Sensitive ◽  
Label Free Detection

Target-induced structure switching of DNA for label-free and ultrasensitive electrochemiluminescent detection of proteins

2014 ◽  
Vol 50 (24) ◽  
pp. 3211-3213 ◽  
Author(s):  
Mengli Yang ◽  
Ying Chen ◽  
Yun Xiang ◽  
Ruo Yuan ◽  
Yaqin Chai
Keyword(s):  
Dna Structure ◽  
Label Free ◽  
Switching Strategy ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Exo Iii ◽  
Recycling Amplification ◽  
Structure Switching ◽  
Induced Structure

Highly sensitive and label-free detection of thrombin is achieved via a target-induced DNA structure switching strategy and Exo III-assisted recycling amplification.

scholarly journals Chiral Plasmonic Biosensors

Biosensors ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 120 ◽  
Author(s):  
Vladimir Bochenkov ◽  
Tatyana Shabatina
Keyword(s):  
Refractive Index ◽  
Surface Plasmon Resonance ◽  
Plasmonic Nanostructures ◽  
Label Free ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Recent Developments ◽  
Detection Of Biomolecules ◽  
Local Refractive Index ◽  
Unique Capability

Biosensing requires fast, selective, and highly sensitive real-time detection of biomolecules using efficient simple-to-use techniques. Due to a unique capability to focus light at nanoscale, plasmonic nanostructures provide an excellent platform for label-free detection of molecular adsorption by sensing tiny changes in the local refractive index or by enhancing the light-induced processes in adjacent biomolecules. This review discusses the opportunities provided by surface plasmon resonance in probing the chirality of biomolecules as well as their conformations and orientations. Various types of chiral plasmonic nanostructures and the most recent developments in the field of chiral plasmonics related to biosensing are considered.

Gold nanoparticle integrated artificial nanochannels for label-free detection of peroxynitrite

2021 ◽  
Author(s):  
Jing Wu ◽  
Xing Wang ◽  
Lei Ge ◽  
Rui Lv ◽  
Fan Zhang ◽  
...  
Keyword(s):  
Small Molecules ◽  
Gold Nanoparticle ◽  
Sensitive Detection ◽  
Label Free ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Highly Sensitive Detection

A label-free method for rapid and highly sensitive detection of ONOO− was proposed by employing ABEI@AuNPs integrated nanochannels. This work paves a new way to develop a versatile platform for the detection of different biological small molecules.

scholarly journals Responsive Janus Structural Color Hydrogel Micromotors for Label-Free Multiplex Assays

Research ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Huan Wang ◽  
Lijun Cai ◽  
Dagan Zhang ◽  
Luoran Shang ◽  
Yuanjin Zhao
Keyword(s):  
Detection Efficiency ◽  
Multiplex Assay ◽  
Detection Sensitivity ◽  
Structural Color ◽  
Label Free ◽  
Structural Colors ◽  
Multiplex Assays ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Coding Capacity

Micromotors with self-propelling ability demonstrate great values in highly sensitive analysis. Developing novel micromotors to achieve label-free multiplex assay is particularly intriguing in terms of detection efficiency. Herein, structural color micromotors (SCMs) were developed and employed for this purpose. The SCMs were derived from phase separation of droplet templates and exhibited a Janus structure with two distinct sections, including one with structural colors and the other providing catalytic self-propelling functions. Besides, the SCMs were functionalized with ion-responsive aptamers, through which the interaction between the ions and aptamers resulted in the shift of the intrinsic color of the SCMs. It was demonstrated that the SCMs could realize multiplex label-free detection of ions based on their optical coding capacity and responsive behaviors. Moreover, the detection sensitivity was greatly improved benefiting from the autonomous motion of the SCMs which enhanced the ion-aptamer interactions. We anticipate that the SCMs can significantly promote the development of multiplex assay and biomedical fields.

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