Duodenal-jejunal bypass maintains hepatic S-adenosylmethionine/S-homocysteine ratio in diet-induced obese rats

Author(s):  
Mikyung Kim ◽  
Yunmee Rho ◽  
Rhoeun Park ◽  
Jeeyoun Jung ◽  
Geum-Sook Hwang ◽  
...  
Keyword(s):  
2014 ◽  
Vol 25 (4) ◽  
pp. 656-665 ◽  
Author(s):  
Maria Lúcia Bonfleur ◽  
Rosane Aparecida Ribeiro ◽  
Audrei Pavanello ◽  
Raul Soster ◽  
Camila Lubaczeuski ◽  
...  

Endocrine ◽  
2018 ◽  
Vol 60 (3) ◽  
pp. 407-414 ◽  
Author(s):  
Mariana Carla Mendes ◽  
Maria Lúcia Bonfleur ◽  
Rosane Aparecida Ribeiro ◽  
Camila Lubaczeuski ◽  
Ana Flavia Justino Fêo ◽  
...  

Author(s):  
Vanessa Marieli CEGLAREK ◽  
Zoé Maria GUARESCHI ◽  
Gabriela MOREIRA-SOARES ◽  
Rafaela Cristiane ECKER-PASSARELLO ◽  
Sandra Lucinei BALBO ◽  
...  

ABSTRACT Background: Thermogenic activity in the brown adipose tissue (BAT) of obese individuals is reduced, and this condition may be modified by bariatric surgery (BS). Aim: To characterize fat deposition in BAT from hypothalamic obese (HyO) rats submitted to duodenal-jejunal-bypass (DJB) surgery. Methods: For induction of hypothalamic obesity, newborn male Wistar rats were treated with subcutaneous injections of monosodium glutamate (MSG). The control (CTL) group received saline solution. At 90 days, the HyO rats were submitted to DJB or sham operation, generating the HyO-DJB and HyO-SHAM groups. At 270 days, the rats were euthanized, and the BAT was weighed and submitted to histological analysis. Results: Compared to BAT from CTL animals, the BAT from HyO-SHAM rats displayed increased weight, hypertrophy with greater lipid accumulation and a reduction in nucleus number. DJB effectively increased nucleus number and normalized lipid deposition in the BAT of HyO-SHAM rats, similar to that observed in CTL animals. Conclusion: DJB surgery avoided excessive lipid deposition in the BAT of hypothalamic obese rats, suggesting that this procedure could reactivate thermogenesis in BAT, and contribute to increase energy expenditure.


2017 ◽  
Vol 32 (1) ◽  
pp. 1-13
Author(s):  
Bruna Hart Ulsenheimer ◽  
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Heloisa Deola Confortim ◽  
Léslie Cazetta Jeronimo ◽  
Lígia Aline Centenaro ◽  
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2012 ◽  
Vol 22 (5) ◽  
pp. 819-826 ◽  
Author(s):  
Allan Cezar Faria Araujo ◽  
Maria Lúcia Bonfleur ◽  
Sandra Lucinei Balbo ◽  
Rosane Aparecida Ribeiro ◽  
Alexandre Coutinho Teixeira de Freitas

2015 ◽  
Vol 25 (10) ◽  
pp. 1966-1975 ◽  
Author(s):  
Bo Xu ◽  
Xiaojie Yan ◽  
Yikai Shao ◽  
Qiwei Shen ◽  
Rong Hua ◽  
...  

2019 ◽  
Vol Volume 12 ◽  
pp. 149-159
Author(s):  
Hsin-Hsien Yu ◽  
Mao-Chih Hsieh ◽  
Szu-Yuan Wu ◽  
Edgar D Sy ◽  
Yan-Shen Shan

Surgery Today ◽  
2013 ◽  
Vol 44 (2) ◽  
pp. 340-348 ◽  
Author(s):  
Hirofumi Imoto ◽  
Chikashi Shibata ◽  
Fumie Ikezawa ◽  
Daisuke Kikuchi ◽  
Soutoku Someya ◽  
...  

2014 ◽  
Vol 29 (9) ◽  
pp. 609-614 ◽  
Author(s):  
Claudia Emanuelli Ebertz ◽  
Maria Lúcia Bonfleur ◽  
Iala Milene Bertasso ◽  
Mariana Carla Mendes ◽  
Camila Lubaczeuski ◽  
...  

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