A thiazolo[4,5-b]pyridine-based fluorescent probe for detection of zinc ions and application for in vitro and in vivo bioimaging

Talanta ◽  
2018 ◽  
Vol 185 ◽  
pp. 396-404 ◽  
Author(s):  
Jiao Gong ◽  
Yuan-heng Li ◽  
Chan-juan Zhang ◽  
Jian Huang ◽  
Qi Sun
Keyword(s):  
RSC Advances ◽  
2015 ◽  
Vol 5 (104) ◽  
pp. 85957-85963 ◽  
Author(s):  
Peng Wang ◽  
Ke Wang ◽  
Dan Chen ◽  
Yibo Mao ◽  
Yueqing Gu

A novel NIR fluorescent probe (DCM-B2) based on dicyanomethylene-4H-pyran was synthesized for the detection of H2O2.


2020 ◽  
Vol 44 (28) ◽  
pp. 12107-12112 ◽  
Author(s):  
Yunyan Zhang ◽  
Xiuqi Kong ◽  
Yonghe Tang ◽  
Min Li ◽  
Yaguang Yin ◽  
...  

A novel ratiometric fluorescent probe, Hcy-CO, with long-wavelength emission was developed for visualizing CO in living cells and zebrafish.


The Analyst ◽  
2019 ◽  
Vol 144 (12) ◽  
pp. 3807-3816 ◽  
Author(s):  
Xiaojun He ◽  
Chenglin Wu ◽  
Yuna Qian ◽  
Yahui Li ◽  
Lilei Zhang ◽  
...  

Here reported an NBDT sensor could be effectively responsive to gallium and chromium for bio-imaging in vivo.


Author(s):  
Aiqing Feng ◽  
Yongmei Jia ◽  
Liping Huang ◽  
Lin Wang ◽  
Guohua Zhou ◽  
...  

Cancers ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 470 ◽  
Author(s):  
Surendra Punganuru ◽  
Hanumantha Madala ◽  
Viswanath Arutla ◽  
Kalkunte Srivenugopal

Human NAD(P)H quinone oxidoreductase-1 (hNQO1) is an important cancer-related biomarker, which shows significant overexpression in malignant cells. Developing an effective method for detecting NQO1 activity with high sensitivity and selectivity in tumors holds a great potential for cancer diagnosis, treatment, and management. In the present study, we report a new dicyanoisophorone (DCP) based fluorescent probe (NQ-DCP) capable of monitoring hNQO1 activity in vitro and in vivo in both ratiometric and turn-on model. NQ-DCP was prepared by conjugating dicyanoisophorone fluoroprobe with hNQO1 activatable quinone propionic acid (QPA), which remain non-fluorescent until activation by tumor-specific hNQO1. NQ-DCP featured a large Stokes shift (145 nm), excellent biocompatibility, cell permeability, and selectivity towards hNQO1 allowed to differentiate cancer cells from healthy cells. We have successfully employed NQ-DCP to monitor non-invasive endogenous hNQO1 activity in brain tumor cells in vitro and in xenografted tumors developed in nude mice.


2017 ◽  
Vol 1 (4) ◽  
pp. 660-667 ◽  
Author(s):  
Xianfeng Hou ◽  
Jin Peng ◽  
Fang Zeng ◽  
Changmin Yu ◽  
Shuizhu Wu

The AFU level in the HCC model of zebrafish can be mapped by using a novel single-fluorophore based ratiometric fluorescent probe.


2017 ◽  
Vol 91 ◽  
pp. 849-856 ◽  
Author(s):  
Sathyadevi Palanisamy ◽  
Pei-Yu Wu ◽  
Shou-Cheng Wu ◽  
Yu-Jen Chen ◽  
Shey-Cherng Tzou ◽  
...  

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