MoS2@Ti3C2 nanohybrid-based photoelectrochemical biosensor: A platform for ultrasensitive detection of cancer biomarker exosomal miRNA

Talanta ◽  
2021 ◽  
pp. 123077
Author(s):  
Zhiwei Sun ◽  
Yao Tong ◽  
Li Zhao ◽  
Juan Li ◽  
Fucheng Gao ◽  
...  
Keyword(s):  
Cancer Biomarker ◽  
Ultrasensitive Detection ◽  
Photoelectrochemical Biosensor ◽  
Exosomal Mirna

Ultrasensitive detection of cancer biomarker microRNA by amplification of fluorescence of lanthanide nanoprobes

Nano Research ◽  
2017 ◽  
Vol 11 (1) ◽  
pp. 264-273 ◽  
Author(s):  
Lianyu Lu ◽  
Datao Tu ◽  
Yan Liu ◽  
Shanyong Zhou ◽  
Wei Zheng ◽  
...  
Keyword(s):  
Cancer Biomarker ◽  
Ultrasensitive Detection

CuO/Cu2O nanowire array photoelectrochemical biosensor for ultrasensitive detection of tyrosinase

2020 ◽  
Vol 63 (7) ◽  
pp. 1012-1018 ◽  
Author(s):  
Xiaoxi Guo ◽  
Jinghua Wu ◽  
Lian Xia ◽  
Meihao Xiang ◽  
Fengli Qu ◽  
...  
Keyword(s):  
Nanowire Array ◽  
Ultrasensitive Detection ◽  
Photoelectrochemical Biosensor

scholarly journals Microfluidic electrochemical immunoarray for ultrasensitive detection of two cancer biomarker proteins in serum

2011 ◽  
Vol 26 (11) ◽  
pp. 4477-4483 ◽  
Author(s):  
Bhaskara V. Chikkaveeraiah ◽  
Vigneshwaran Mani ◽  
Vyomesh Patel ◽  
J. Silvio Gutkind ◽  
James F. Rusling
Keyword(s):  
Cancer Biomarker ◽  
Ultrasensitive Detection

scholarly journals Biofunctionalized two-dimensional Ti3C2 MXenes for ultrasensitive detection of cancer biomarker

2018 ◽  
Vol 121 ◽  
pp. 243-249 ◽  
Author(s):  
Saurabh Kumar ◽  
Yongjiu Lei ◽  
Niman H. Alshareef ◽  
M.A. Quevedo-Lopez ◽  
Khaled N. Salama
Keyword(s):  
Cancer Biomarker ◽  
Ultrasensitive Detection ◽  
Two Dimensional

scholarly journals Electrochemical Sandwich Immunoassay for the Ultrasensitive Detection of Human MUC1 Cancer Biomarker

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Zahra Taleat ◽  
Cecilia Cristea ◽  
Giovanna Marrazza ◽  
Robert Săndulescu
Keyword(s):  
Magnetic Beads ◽  
Electrochemical Sensors ◽  
Differential Pulse ◽  
Blocking Agent ◽  
Cancer Biomarker ◽  
Sandwich Immunoassay ◽  
Ultrasensitive Detection ◽  
Human Muc1 ◽  
Pulse Voltammetry ◽  
Secondary Antibodies

A new electrochemical sandwich immunoassay for the ultrasensitive detection of human MUC1 cancer biomarker using protein G-functionalized magnetic beads (MBs) and graphite-based screen-printed electrodes (SPEs) was developed. Magnetic beads were employed as the platforms for the immobilization and immunoreaction process. A pair of primary and secondary antibodies was used to capture the MUC1 protein. After labeling with a third antibody conjugated with horseradish peroxidase (HRP), the resulting conjugate was trapped at the surface of the graphite-based SPEs and MUC1 determination was carried out by differential pulse voltammetry (DPV) at 0.4 V upon H2O2addition using acetaminophen (APAP) as the redox mediator. A linear relationship was obtained for the detection of human MUC1 over a range of 0–25 ppb with the lowest detection limit of 1.34 ppb when HRP was applied as a label. Preliminary experiments were performed using disposable electrochemical sensors in order to optimize some parameters (i.e., incubation times, concentrations, and blocking agent).

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