Self-assembling of supramolecular adducts by sulfonato-calix[4]arene and pyridinium gemini guests in neutral aqueous solution

2017 ◽  
Vol 656 ◽  
pp. 47-52 ◽  
Author(s):  
Carmela Bonaccorso ◽  
Rossella Migliore ◽  
Mariia A. Volkova ◽  
Giuseppe Arena ◽  
Carmelo Sgarlata
Keyword(s):  
Aqueous Solution ◽  
Self Assembling ◽  
Neutral Aqueous Solution

scholarly journals Binding Affinity and Driving Forces for the Interaction of Calixarene-Based Micellar Aggregates With Model Antibiotics in Neutral Aqueous Solution

2021 ◽  
Vol 8 ◽  
Author(s):  
Rossella Migliore ◽  
Giuseppe Granata ◽  
Andrea Rivoli ◽  
Grazia Maria Letizia Consoli ◽  
Carmelo Sgarlata
Keyword(s):  
Aqueous Solution ◽  
Nmr Spectra ◽  
Drug Delivery Systems ◽  
Driving Forces ◽  
Titration Calorimetry ◽  
Self Assembling ◽  
Micellar Aggregates ◽  
Nanostructured Systems ◽  
Neutral Aqueous Solution

The search for novel surfactants or drug delivery systems able to improve the performance of old-generation antibiotics is a topic of great interest. Self-assembling amphiphilic calix[4]arene derivatives provide well-defined nanostructured systems that exhibit promising features for antibiotics delivery. In this work, we investigated the capability of two micellar polycationic calix[4]arene derivatives to recognize and host ofloxacin, chloramphenicol, or tetracycline in neutral aqueous solution. The formation of the nanoaggregates and the host–guest equilibria were examined by nano-isothermal titration calorimetry, dynamic light scattering, and mono- and bi-dimensional NMR. The thermodynamic characterization revealed that the calix[4]arene-based micellar aggregates are able to effectively entrap the model antibiotics and enabled the determination of both the species and the driving forces for the molecular recognition process. Indeed, the formation of the chloramphenicol–micelle adduct was found to be enthalpy driven, whereas entropy drives the formation of the adducts with both ofloxacin and tetracycline. NMR spectra corroborated ITC data about the positioning of the antibiotics in the calixarene nanoaggregates.

A Highly Sensitive and Selective Fluorescent Chemodosimeter for Hg2+ in Neutral Aqueous Solution

2007 ◽  
Vol 17 (5) ◽  
pp. 460-465 ◽  
Author(s):  
Fang-Ying Wu ◽  
Yong-Qiang Zhao ◽  
Zhao-Jun Ji ◽  
Yu-Mei Wu
Keyword(s):  
Aqueous Solution ◽  
Highly Sensitive ◽  
Neutral Aqueous Solution ◽  
Fluorescent Chemodosimeter

THE CHEMISTRY OF ETHYLENE OXIDE: V. THE REACTION OF ETHYLENE OXIDE WITH HALIDE IONS IN NEUTRAL AND ACID SOLUTION

1952 ◽  
Vol 30 (3) ◽  
pp. 169-176 ◽  
Author(s):  
A. M. Eastham ◽  
G. A. Latremouille
Keyword(s):  
Aqueous Solution ◽  
Ethylene Oxide ◽  
Acid Solution ◽  
Activation Energies ◽  
Hydrogen Halide ◽  
Halide Ions ◽  
Neutral Aqueous Solution ◽  
Rate Of Hydrolysis ◽  
Acid Catalyzed ◽  
Hydrolysis Of

The rates of reaction of halide ions with ethylene oxide in neutral aqueous solution and the rate of hydrolysis of ethylene oxide in acid solution have been measured and the activation energies determined. From these data and from the ratio of glycol to chlorohydrin formed when ethylene oxide reacts with excess aqueous hydrogen halide, the rates of the acid-catalyzed addition of halide ions to ethylene oxide at 25 °C. have been estimated.

Self-assembled nano-aggregates of fluorinases demonstrate enhanced enzymatic activity, thermostability and reusability

2020 ◽  
Vol 8 (2) ◽  
pp. 648-656
Author(s):  
Chunhao Tu ◽  
Jin Zhou ◽  
Lei Peng ◽  
Shuli Man ◽  
Long Ma
Keyword(s):  
Aqueous Solution ◽  
Enzyme Activity ◽  
Enzymatic Activity ◽  
Self Assembling ◽  
Self Assembled

Three SAP (self-assembling peptide)-tagged fluorinases (FLAs) are successfully prepared. All three SAP-tagged FLAs bear enzymatic activity and they form nano-sized particles in aqueous solution. One of them displays improved enzyme activity, thermostability and reusability.

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