Dithioates of Meldrum’s acid, dimedone, and barbituric acid, novel sulfur transfer reagents for the one-pot copper-catalyzed conversion of aryl iodides into diaryl disulfides

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.

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NiO nanoparticles: A highly efficient catalyst for the one-pot three-component synthesis of pyrano [2, 3-d] pyrimidine derivatives in green media.

Letters in Organic Chemistry ◽

10.2174/1570178618666211001115655 ◽

2021 ◽

Vol 18 ◽

Author(s):

Ellahe Sabbaghnasab ◽

Enayatollah Sheikhhosseini

Keyword(s):

Barbituric Acid ◽

Nio Nanoparticles ◽

Pyrimidine Derivatives ◽

One Pot ◽

Efficient Catalyst ◽

Environmental Friendliness ◽

Short Reaction Time ◽

Pyrimidine Synthesis ◽

Simple Processing ◽

The One

: NiO nanoparticles are utilized to effectively strengthen annulated pyrano [2, 3- d] pyrimidine synthesis through primary Knoevenagel, following Micheal and ultimate heterocyclization reactions of aldehyde, malononitrile, and barbituric acid. The characteristics of NiO nanoparticles are identified using advanced techniques, such as IR, UV, EDX, XRD, SEM, and TEM. The nano-NiO particles are mostly below < 100 nm in size with uniform spherical shapes. The adopted approach is advantages thanks to its simple processing, relatively short reaction time, often good to high average yields, convenient workability, and environmental friendliness.

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One-pot Green Synthesis of 3-Methyl-4-aryl-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridine-6-ones by Multicomponent Assembling of 5-Methylpyrazol-3-amine, Aldehydes, and Meldrum's Acid Using Sodium Dodecyl Sulfate (SDS) in Water

Journal of Heterocyclic Chemistry ◽

10.1002/jhet.2723 ◽

2016 ◽

Vol 54 (2) ◽

pp. 1640-1644 ◽

Cited By ~ 5

Author(s):

Saba Hemmati ◽

Parisa Safarimehr ◽

Maryam Safaei ◽

Malak Hekmati

Keyword(s):

Sodium Dodecyl Sulfate ◽

Green Synthesis ◽

Sodium Dodecyl ◽

Meldrum's Acid ◽

Meldrum’S Acid ◽

One Pot ◽

Dodecyl Sulfate

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Efficient Cu-catalyzed base-free C–S coupling under conventional and microwave heating. A simple access to S-heterocycles and sulfides

Beilstein Journal of Organic Chemistry ◽

10.3762/bjoc.9.50 ◽

2013 ◽

Vol 9 ◽

pp. 467-475 ◽

Cited By ~ 26

Author(s):

Silvia M Soria-Castro ◽

Alicia B Peñéñory

Keyword(s):

Microwave Irradiation ◽

Microwave Heating ◽

Catalytic System ◽

Low Cost ◽

One Pot ◽

Alkyl Aryl ◽

One Pot Synthesis ◽

Aryl Iodides ◽

The One ◽

Aryl Sulfides

S-aryl thioacetates can be prepared by reaction of inexpensive potassium thioacetate with both electron-rich and electron-poor aryl iodides under a base-free copper/ligand catalytic system. CuI as copper source affords S-aryl thioacetates in good to excellent yields, by using 1,10-phenanthroline as a ligand in toluene at 100 °C after 24 h. Under microwave irradiation the time was drastically reduced to 2 h. Both procedures are simple and involve a low-cost catalytic system. This methodology was also applied to the “one-pot” synthesis of target heterocycles, such as 3H-benzo[c][1,2]dithiol-3-one and 2-methylbenzothiazole, alkyl aryl sulfides, diaryl disulfides and asymmetric diaryl sulfides in good yields.

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