Electrogenerated base-promoted synthesis of 5-aryl-5,6-dihydro-2H-pyrano[2,3-d]pyrimidine-2,4,7-triones by multicomponent assembly of barbituric acid, aldehydes and Meldrum's acid at room temperature

RSC Advances ◽  
2014 ◽  
Vol 4 (98) ◽  
pp. 55313-55317 ◽  
Author(s):  
Hojat Veisi ◽  
Abbas Maleki ◽  
Zahra Omrani ◽  
Shahram Lotfi
Keyword(s):  
Room Temperature ◽  
Barbituric Acid ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot

An electrochemical strategy for the synthesis of pyrano[2,3-d]pyrimidine-2,4,7-triones via a one-pot, three component condensation is described.

scholarly journals One Pot, Four Component Synthesis of Phthalazine-1,4-diones Derivatives in [BMIM][OH] Medium

2019 ◽  
Vol 32 (1) ◽  
pp. 45-48
Author(s):  
D.P. Loka Maheshwari ◽  
B. Satyanarayana
Keyword(s):  
Reaction Time ◽  
Room Temperature ◽  
Diethyl Phthalate ◽  
High Yield ◽  
Efficient Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot

[BMIM][OH] mediated, green and efficient synthesis of phthalazines (5) have been developed by condensing diethyl phthalate (1), ethyl cyanohydrazide (2), substituted benzaldehyde (3) and malononitrile (4) in the presence of Meldrum’s acid at 60-65 °C and at room temperature for 60-90 min. The importance of this method includes shorter reaction time and high yield.

An Expeditious One-Pot Three-Component Synthesis of 4-Aryl-3,4-dihydrobenzo[g] quinoline-2,5,10(1H)-triones under Green Conditions

2020 ◽  
Vol 23 (23) ◽  
pp. 2626-2634
Author(s):  
Saiedeh Kamalifar ◽  
Hamzeh Kiyani
Keyword(s):  
Reaction Medium ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
First Time ◽  
Green Conditions

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.

One Pot Synthesis of Monoalkylated and Mixed, Dialkylated Meldrum's Acid Derivatives

2004 ◽  
Vol 34 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Uday V. Desai ◽  
D. M. Pore ◽  
R. B. Mane ◽  
S. B. Solabannavar ◽  
P. P. Wadgaonkar
Keyword(s):  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Meldrum's Acid Derivatives

Meldrum's acid in organic synthesis. 1. A convenient one-pot synthesis of ethyl indolepropionates

1978 ◽  
Vol 19 (20) ◽  
pp. 1759-1762 ◽  
Author(s):  
Yuji Oikawa ◽  
Hitoshi Hirasawa ◽  
Osamu Yonemitsu
Keyword(s):  
Organic Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis
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