The effect of solvents on the conformations of Amyloid β-peptide (1–42) studied by molecular dynamics simulation

2009 ◽  
Vol 895 (1-3) ◽  
pp. 1-8 ◽  
Author(s):  
Cao Yang ◽  
Jinyu Li ◽  
Yu Li ◽  
Xiaolei Zhu
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulation ◽  
Amyloid Β ◽  
Dynamics Simulation ◽  
Amyloid Β Peptide ◽  
Effect Of Solvents

Investigation of the interaction of amyloid β peptide (11–42) oligomers with a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membrane using molecular dynamics simulation

2018 ◽  
Vol 20 (10) ◽  
pp. 6817-6829 ◽  
Author(s):  
Ning Xiang ◽  
Yuan Lyu ◽  
Xiao Zhu ◽  
Ganesan Narsimhan
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulation ◽  
Pore Formation ◽  
Amyloid Β ◽  
Dynamics Simulation ◽  
Amyloid Β Peptide ◽  
Aβ Oligomers ◽  
Aβ Peptides ◽  
Amyloid Aβ ◽  
Β Amyloid

The mechanism of pore formation in model neural cell membranes by β amyloid (Aβ) peptides was investigated using molecular dynamics simulation which indicated that Aβ oligomers of size equal or greater than 3 has a higher tendency for pore formation than monomers and that cholesterol tends to retard Aβ binding and insertion into the membrane.

scholarly journals Molecular dynamics simulation of aluminium binding to amyloid-β and its effect on peptide structure

PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0217992 ◽  
Author(s):  
Matthew Turner ◽  
Shaun T. Mutter ◽  
Oliver D. Kennedy-Britten ◽  
James A. Platts
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulation ◽  
Amyloid Β ◽  
Dynamics Simulation ◽  
Peptide Structure
Sign in / Sign up

Export Citation Format

Share Document