scholarly journals Autologous serum therapy in recalcitrant laser-assisted in situ keratomileusis-induced neurotrophic epitheliopathy

2015 ◽  
Vol 5 (3) ◽  
pp. 109-113 ◽  
Author(s):  
Shan-Jiun Lin ◽  
Chien-Chia Su ◽  
David C.K. Chang ◽  
Brian Hsi ◽  
Fung-Rong Hu ◽  
...  
Keyword(s):  
Autologous Serum ◽  
Serum Therapy

scholarly journals Clinical Outcome of Autologous Serum Therapy in Chronic Idiopathic Urticaria

2017 ◽  
Vol 15 (1) ◽  
pp. 71-74 ◽  
Author(s):  
Dharmendra Karn ◽  
Shekhar KC
Keyword(s):  
Skin Prick Test ◽  
Chronic Urticaria ◽  
Statistical Significance ◽  
Cost Effective ◽  
Chronic Idiopathic Urticaria ◽  
Autologous Serum ◽  
P Value ◽  
Prick Test ◽  
H1 Antihistamines ◽  
Serum Therapy

Background: Quality of life in chronic idiopathic urticaria is hampered as efficacy of H1-antihistamines is limited. Autologous serum containing tolerance-generating anti-idiotype antibodies is a novel and cost-effective therapy. This study was conducted to evaluate the efficacy of autologous serum therapy (AST) among chronic urticaria patients with autologous skin prick test positive and negative status.Methods: Untreated 102 patients of chronic urticaria were enrolled in a non-randomized interventional study. Patients were categorized into two groups based on autologous serum skin prick test as test positive (ASST +) and test negative (ASST -). Patients were then treated with intramuscular injection of 0.05ml per kg body weight of autologous serum weekly for 10 weeks. Urticaria activity scoring (UAS) tool was used for quantification of the symptoms. Weekly recording of UAS (range: 0-42) was made before the therapy (baseline) and during the therapy for 10 weeks.Results: Significant improvement with AST in the mean UAS was noted from baseline to 10 weeks in both the group of patients (14.6 ± 6.3 and 10.2 ± 5.1 for ASST+ group; 16.9 ± 7.8 and 8.6 ± 4.8 for ASST- group; at baseline and 10 weeks, respectively (p-value for both <0.05)). However no statistical significance was found while comparing the efficacy of the therapy against ASST + and ASST - Groups (p-value > 0.05).Conclusions: Irrespective of autologous skin prick test results, autologous serum therapy showed significant improvement in patients with chornic idiopathic urticaria. AST can, thus, be an effective treatment modality for it.

scholarly journals EFFECTIVENESS OF AUTOLOGOUS SERUM THERAPY IN CHRONIC URTICARIA: A PROSPECTIVE OBSERVATIONAL STUDY IN TERTIARY CARE HOSPITAL

2016 ◽  
Vol 5 (17) ◽  
pp. 822-827
Author(s):  
Rakesh Kumar Patel ◽  
Anil Kumar Gupta ◽  
Santosh Kumar Singh ◽  
Harleen Chhachhi ◽  
Pawan Kumar Patel ◽  
...  
Keyword(s):  
Observational Study ◽  
Chronic Urticaria ◽  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Autologous Serum ◽  
Care Hospital ◽  
Serum Therapy

scholarly journals Autologous serum therapy in chronic urticaria: Old wine in a new bottle

2008 ◽  
Vol 74 (2) ◽  
pp. 109 ◽  
Author(s):  
AK Bajaj ◽  
Abir Saraswat ◽  
Amitabh Upadhyay ◽  
Rajetha Damisetty ◽  
Sandipan Dhar
Keyword(s):  
Chronic Urticaria ◽  
Autologous Serum ◽  
Serum Therapy

Evaluation of the Role of Umbilical Cord Serum and Autologous Serum Therapy in Reepithelialization After Keratoplasty

2017 ◽  
Vol 43 (5) ◽  
pp. 324-329 ◽  
Author(s):  
Neha Kamble ◽  
Namrata Sharma ◽  
Prafulla K. Maharana ◽  
Pooja Bandivadekar ◽  
Ritu Nagpal ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
Autologous Serum ◽  
Cord Serum ◽  
Serum Therapy

scholarly journals Autologous serum therapy in chronic urticaria

2019 ◽  
Vol 5 (4) ◽  
pp. 275-279
Author(s):  
Surendran K A K ◽  
◽  
Nanjundaswamy B L ◽  
Sathish S ◽  
Bangaru H ◽  
...  
Keyword(s):  
Chronic Urticaria ◽  
Autologous Serum ◽  
Serum Therapy

scholarly journals Autologous serum therapy in chronic urticaria: A promising complement to antihistamines

2014 ◽  
Vol 59 (4) ◽  
pp. 375 ◽  
Author(s):  
NilayKanti Das ◽  
Panchami Debbarman ◽  
Amrita Sil ◽  
PiyushKanti Datta ◽  
Debabrata Bandyopadhyay
Keyword(s):  
Chronic Urticaria ◽  
Autologous Serum ◽  
Serum Therapy

scholarly journals Autologous Serum Eye Drops for Post-Chemical Injuries and Corneal Epithelial Defects

2013 ◽  
Vol 1 (1) ◽  
pp. 45-49
Author(s):  
Mirjana A. Janicijevic-Petrovic ◽  
Marko Petrovic ◽  
Dragan Vujic ◽  
Katarina Janicijevic ◽  
Andrijana Popovic
Keyword(s):  
Success Rate ◽  
Conventional Treatment ◽  
Complete Healing ◽  
Autologous Serum ◽  
Eye Drops ◽  
Epithelial Defect ◽  
Corneal Epithelial ◽  
Chemical Injuries ◽  
Serum Therapy ◽  
Serum Eye Drops

Aim: To evaluate success rate (efficacy, safety) in treatment of post-chemical injuries and corneal defects using autologous serum eye drops.Material and Methods: Authors reviewed 93 patients (116 eyes) hospitalized in Clinic of ophthalmology from 2010 to 2013, who had post-causoma corneal defects that were nonresponsive to conventional treatment and were treated with serum therapy. Authors correlated time of epithelialization of defects with rate of epithelial healing.Results: Authors investigated 93 patients (52 males, 41 females; aged 18 - 74) for treatment of corneal defects. Application of autologous serum therapy 56 (48.28%) of 116 eyes was healed in an average time of 4 weeks. Among 116 eyes, epithelial defects healed in 4 (3.45%) within 1 week, in additional 17 (14.65%) in 1-2 weeks, totalling 31 (26.72%) within 3 weeks. Five eyes (4.31%) completely healed at 5 week; three eyes (2.59%) had subsequent healing of epithelial defect at 6 week; 56 eyes completely healed within one month, and the remaining eight eyes healed within 1.5 month.Conclusion: Using serum therapy, it was managed to reduce time of healing from eleven weeks, which were necessary just couple years ago (before 2010) to four (maximum six) weeks to complete healing which are necessary today.

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