scholarly journals Clinical performance evaluation of Elecsys HIV Duo, Anti-HCV II, HBsAg II, Anti-HBc II, and Syphilis assays for routine screening of first-time blood donor samples at a French blood donation center

2021 ◽  
Author(s):  
Claude Maugard ◽  
Josiane Relave ◽  
Markus Klinkicht ◽  
Cecile Fabra
Keyword(s):  
Performance Evaluation ◽  
Blood Donor ◽  
Blood Donation ◽  
Clinical Performance ◽  
Routine Screening ◽  
First Time

scholarly journals The Development of a Social Networking�Based Relatedness Intervention Among Young, First-Time Blood Donors: Pilot Study (Preprint)

2017 ◽  
Author(s):  
Victoria Frye ◽  
Louisa Duffy ◽  
Janis L France ◽  
Debra A Kessler ◽  
Mark Rebosa ◽  
...  
Keyword(s):  
Social Networking ◽  
Social Relations ◽  
Blood Donor ◽  
Blood Donation ◽  
Pilot Trial ◽  
Random Order ◽  
Internal Motivation ◽  
Donation Behavior ◽  
First Time ◽  
Intervention Condition

BACKGROUND Increasing repeat blood donation behavior is a critical public health goal. According to self-determination theory, the process of developing internal motivation to give blood and an associated self-identity as a blood donor may be promoted by feelings of “relatedness” or a connection to other donors, which may be enhanced through social relations and interactions. OBJECTIVE The purpose of this report it to describe the development and pilot testing of a social networking-based (Facebook) intervention condition designed to increase feelings of relatedness via virtual social interaction and support. METHODS To develop the intervention condition content, images, text, polls, and video content were assembled. Ohio University college students (N=127) rated the content (82 images/text) presented by computer in random order using a scale of one to five on various dimensions of relatedness. Mean ratings were calculated and analyses of variance were conducted to assess associations among the dimensions. Based on these results, the relatedness intervention was adapted and evaluated for feasibility, acceptability, and preliminary efficacy among 24 first-time donors, aged 18 to 24 years, in a 30-day pilot trial. Paired t-tests were conducted to examine change over time in relatedness and connectedness. RESULTS The intervention condition that was developed was acceptable and feasible. Results of the uncontrolled, preintervention, and postintervention evaluation revealed that feelings of individual-level relatedness increased significantly after the intervention. CONCLUSIONS By promoting first-time blood donor relatedness, our goal is to enhance internal motivation for donating and the integration of the blood donor identity, thus increasing the likelihood of future repeat donation. CLINICALTRIAL ClinicalTrials.gov NCT02717338; https://clinicaltrials.gov/ct2/show/NCT02717338 (Archived by WebCite at http://www.webcitation.org/6ymHRBCwu)

scholarly journals A STUDY OF ADVERSE REACTIONS IN WHOLE BLOOD DONORS IN VADODARA, GUJARAT.

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Dr. Rahul Rajvanshi ◽  
Dr. Farzana Kothari ◽  
Dr. Milind Dighe ◽  
Dr. Jhalak Patel
Keyword(s):  
Blood Donor ◽  
Blood Donors ◽  
Adverse Reactions ◽  
Blood Donation ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Donor Retention ◽  
Donor Type ◽  
First Time

Background: Voluntary donors normally tolerate blood donation very well, but, occasionally, adverse reactions of variable severity may occur during or at the end of the collection. The occurrence of adverse reactions to blood donation significantly hampers donor retention and negatively impacts on the universal availability of adequate numbers of blood donor units.  Objective: To analyze the spectrum and prevalence of adverse reactions in blood donors in a tertiary care hospital-based blood bank in SSG Hospital, Vadodara.  Materials and Methods: The details of blood donors who presented for donation from January 2107 to April 2019 period were retrieved from the departmental archives for analysis. These included type of donor, type and frequency of adverse reactions to blood donation. Results: The prevalence of adverse reactions to blood donation was (315/35027) 0.9%; this occurred more frequently in first time donors compared to repeat blood donors. Presyncopal reactions were the most frequent adverse reaction encountered among the donors 52.38% (165/315). Conclusion: Presyncopal reactions are common adverse reactions in our blood donor set; this has implications on transfusion safety and blood donor retention. Keywords: Presyncopal reactions, adverse donor reactions, blood donor

scholarly journals Altruism in blood donation: Out of sight out of mind? Closing donation centers influences blood donor lapse

2021 ◽  
Vol 67 ◽  
pp. 102495
Author(s):  
Tjeerd W. Piersma ◽  
René Bekkers ◽  
Wim de Kort ◽  
Eva-Maria Merz
Keyword(s):  
Blood Donor ◽  
Blood Donation

scholarly journals Analytical and Clinical Performance Evaluation of the Elecsys HIV combi PT Assay on the cobas e 602 Analyzer for the Diagnosis of Human Immunodeficiency Virus

2018 ◽  
Vol 151 (4) ◽  
pp. 377-385 ◽  
Author(s):  
Denise L Uettwiller-Geiger ◽  
Marvin Lessig ◽  
Jie An ◽  
Tara Barsch ◽  
Susan Smith ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Performance Evaluation ◽  
Clinical Performance ◽  
Immunodeficiency Virus

scholarly journals Retrospective analysis of the most common cause of rejection of donors for blood donation

2021 ◽  
Vol 8 (3) ◽  
pp. 444
Author(s):  
Garima Vijayvergiya ◽  
Parag Fulzele ◽  
Naveen Vairyamoorthy
Keyword(s):  
Blood Pressure ◽  
Blood Donor ◽  
Blood Donation ◽  
Tertiary Care ◽  
Geographical Area ◽  
Rejection Rate ◽  
Developed Countries ◽  
Care Hospital ◽  
Systemic Examination ◽  
Safe Blood

Background: A significant imbalance in access to safe blood is seen between the developing and developed countries. Donor selection has a pivotal role in preventing transfusion related complications and provide safety to the recipients. In this study, we aimed to find out rate and causes of blood donor rejection in our hospital.  Methods: A retrospective study conducted in a tertiary care hospital involving both the voluntary and replacement donors during the period September 2017 to December 2018. We included all those donors who were considered unfit for blood donation. All those who came for blood donation at our hospital were asked to fill up an enrolment form for a blood donor. A general and systemic examination were done. We calculated the rejection rate, listed the reasons for donor rejection, and analyzed the data.Results: Among 150 rejected blood donors, most were males [129 (86%)], and the rest were females [21 (14%)]. The rejection rate in our study was 3.29%. We found that the rejection rate of donors was different among voluntary and replacement donors. It showed that the most common reason for the temporary rejection of blood donation was low hemoglobin level, followed by abnormal blood pressure.  Conclusions: A vast majority of donors were rejected temporarily [132 (88%)], while the rest of them were rejected permanently [18 (12%)]. Low Hb in females and abnormal blood pressure in males were the commonest causes of blood donor rejection. Many factors affect the similarities and variations between the most typical causes of blood donor rejection, such as geographical area, cultural, socio-economic, and educational factors.  

scholarly journals Clinical performance evaluation of SARS-CoV-2 rapid antigen testing in point of care usage in comparison to RT-qPCR

2021 ◽  
Author(s):  
Isabell Wagenhaeuser ◽  
Kerstin Knies ◽  
Vera Rauschenberger ◽  
Michael Eisenmann ◽  
Miriam McDonogh ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
Viral Load ◽  
Clinical Performance ◽  
Point Of Care ◽  
Hospital Setting ◽  
High Viral Load ◽  
Evaluation Study ◽  
Study Cohort ◽  
Protein Variant ◽  
Atypical Symptoms

Background Antigen rapid diagnostic tests (RDT) for SARS-CoV-2 are fast, broadly available, and inexpensive. Despite this, reliable clinical performance data is sparse. Methods In a prospective performance evaluation study, RDT from three manufacturers (NADAL, Panbio, MEDsan) were compared to quantitative reverse transcription polymerase chain reaction (RT-qPCR) in 5 068 oropharyngeal swabs for detection of SARS-CoV-2 in a hospital setting. Viral load was derived from standardized RT-qPCR Cycle threshold (Ct) values. The data collection period ranged from November 12, 2020 to February 28, 2021. Findings Overall, sensitivity of RDT compared to RT-qPCR was 42.57% (95% CI 33.38%-52.31%), and specificity 99.68% (95% CI 99.48%-99.80%). Sensitivity declined with decreasing viral load from 100% in samples with a deduced viral load of 10^8 SARS-CoV-2 RNA copies per ml to 8.82% in samples with a viral load lower than 104 SARS-CoV-2 RNA copies per ml. No significant differences in sensitivity or specificity could be observed between the three manufacturers, or between samples with and without spike protein variant B.1.1.7. The NPV in the study cohort was 98.84%; the PPV in persons with typical COVID-19 symptoms was 97.37%, and 28.57% in persons without or with atypical symptoms. Interpretation RDT are a reliable method to diagnose SARS-CoV-2 infection in persons with high viral load. RDT are a valuable addition to RT-qPCR testing, as they reliably detect infectious persons with high viral loads before RT-qPCR results are available. Funding German Federal Ministry for Education and Science (BMBF), Free State of Bavaria

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