Assessing the cellular and humoral immune response in Rhipicephalus sanguineus sensu lato (Acari: Ixodidae) infected with Leishmania infantum (Nicolle, 1908)

2018 ◽  
Vol 9 (6) ◽  
pp. 1421-1430 ◽  
Author(s):  
Ana Paula S. Feitosa ◽  
Marlos M. Chaves ◽  
Dyana L. Veras ◽  
Dayse M. Vasconcelos de Deus ◽  
Nairomberg C. Portela ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Leishmania Infantum ◽  
Rhipicephalus Sanguineus ◽  
Humoral Immune ◽  
Rhipicephalus Sanguineus Sensu Lato

Humoral Immune Response of Dogs Immunized with Salivary Gland, Midgut, or Repeated Infestations with Rhipicephalus sanguineus

2006 ◽  
Vol 916 (1) ◽  
pp. 283-288 ◽  
Author(s):  
SATHAPORN JITTAPALAPONG ◽  
ROGER W. STICH ◽  
JOHN C. GORDON ◽  
CATHERINE A. BREMER ◽  
OMAR O. BARRIGA
Keyword(s):  
Immune Response ◽  
Salivary Gland ◽  
Humoral Immune Response ◽  
Rhipicephalus Sanguineus ◽  
Humoral Immune

Role of Yersinia pseudotuberculosis outer proteins (Yops) in murine humoral immune response

2009 ◽  
Vol 54 (3) ◽  
pp. 239-245 ◽  
Author(s):  
J. M. L. Maia ◽  
L. G. S. Monnazzi ◽  
B. M. M. Medeiros
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Yersinia Pseudotuberculosis ◽  
Humoral Immune

scholarly journals Diagnostic and analytical performance evaluation of ten commercial assays for detecting SARS-CoV-2 humoral immune response

2021 ◽  
pp. 113043
Author(s):  
Marnix Mylemans ◽  
Eveline Van Honacker ◽  
Louis Nevejan ◽  
Stefanie van den Bremt ◽  
Laura Hofman ◽  
...  
Keyword(s):  
Immune Response ◽  
Performance Evaluation ◽  
Humoral Immune Response ◽  
Analytical Performance ◽  
Humoral Immune

scholarly journals SARS-CoV-2 RNA and antibodies in tear fluid

2021 ◽  
Vol 6 (1) ◽  
pp. e000733
Author(s):  
Astrid Muyldermans ◽  
Maria Bjerke ◽  
Thomas Demuyser ◽  
Deborah De Geyter ◽  
Ingrid Wybo ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Spike Protein ◽  
Tear Fluid ◽  
Local Response ◽  
Schirmer Test ◽  
Humoral Immune ◽  
Non Invasive ◽  
Reverse Transcription Pcr ◽  
Ocular Symptoms

Background/aimsSARS-CoV-2 is highly contagious. More evidence concerning extrapulmonary transmission routes such as the eyes is urgently needed. Although the humoral immune response is important in the viral containment, the local response in tears has not yet been studied. The aim of our study was twofold: to assess the prevalence of both SARS-CoV-2 RNA and antibodies in tear fluid.MethodsIn a first series, nasopharyngeal sampling and tear sampling by Schirmer test strips were performed in 26 acutely ill patients with COVID-19 to assess the presence of SARS-CoV-2 RNA by reverse transcription PCR. In a second series, IgG and IgA responses to SARS-CoV-2 spike protein in serum and tear fluid of convalescent individuals (n=22) were compared with control individuals (n=15) by ELISA.ResultsSARS-CoV-2 RNA was detected in tears of 7/26 (26.9%) patients with COVID-19. None of them had ocular symptoms. Convalescent individuals displayed a significant higher ratio of IgG (p<0.0001) and IgA (p=0.0068) in tears compared with control individuals. A sensitivity of 77.3% and specificity of 93.3% was observed for IgG, and 59.1% and 100% for IgA.ConclusionsOur results demonstrate the presence of SARS-CoV-2 RNA and a local IgG and IgA immune response in tear fluid. These data confirm the possibility of SARS-CoV-2 transmission through tear fluid and the importance of the eye as a first defence against SARS-CoV-2, indicating the potential of tears as a non-invasive surrogate for serum in monitoring the host immune response.

scholarly journals Successful isolation of Leishmania infantum from Rhipicephalus sanguineus sensu lato (Acari: Ixodidae) collected from naturally infected dogs

2015 ◽  
Vol 11 (1) ◽  
Author(s):  
Viviane Medeiros-Silva ◽  
Rodrigo Gurgel-Gonçalves ◽  
Nadjar Nitz ◽  
Lucia Emilia D’ Anduraim Morales ◽  
Laurício Monteiro Cruz ◽  
...  
Keyword(s):  
Leishmania Infantum ◽  
Rhipicephalus Sanguineus ◽  
Successful Isolation ◽  
Rhipicephalus Sanguineus Sensu Lato
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